The invention provides an earth pressure balance shield mud cake prevention system based on synchronous jet flow. The system comprises a panel fixed sprayer, a cutterhead, a shield body, a soil warehouse separating plate, flushing guns, a flushing position location and tube connection, a high pressure pipeline and pipes, a water separator, a safety valve, a pressure gauge, a high pressure newly increased centrifugal pump, an original centrifugal pump, a base, a water supply pipe, a screw conveyor, a controller and a second trolley. The system provided by the invention has the advantages that working efficiency is high, cost is low, equipment investment is low, operation is simple, no dead angle flushing is carried out on the back of the cutterhead, a bracket of the cutterhead and the soil warehouse separating plate by virtue of the flushing guns at different positions of the soil warehouse separating plate, nozzles of the flushing guns are designed into different specifications, and axial four-hole, axial one-hole and radial four-hole structures are contained, so as to meet flushing requirements of different parts; no dead angle flushing is carried out on a cutter at the center part of the cutterhead by virtue of the panel fixed sprayer of the cutterhead; and mud cake flushing and shield tunneling are synchronous, and mud cake prevention does not influence normal shield tunneling.