The invention provides a spherical surface push-in sealing method using a valve core with a spherical surface to engage a seal base, wherein an initial position is arranged for the valve core, so that the valve core is retained in the initial position before use. When in use, the valve core is pushed out of the initial position by a forward axial force. The valve core moves axially in the valve chamber under the action of the axial forces to close and open the seal. The invention also provides a sealing valve using the sealing method comprising a valve body, a valve core, a seal base. The engaging surface of the valve core and the seal base being a spherical surface, wherein an elastic stand for the valve core is arranged in the valve body and opposite to the initial position for the valve core, a rod is arranged behind the valve core, and an opening is arranged on the valve chamber to communicate with the outside. The pre-tightening force of the seal surface of the invention can be regulated according to different needs. The seal is reliable and constant, and can be used for both the non-refillable sealing valve and the refillable sealing valve.