The invention relates to a new bulk drug in pharmaceuticals industry, and preparation process thereof. The bulk drug of the invention wherein has a weight percentage of more than 98% scutellarin salt.The preparation method is composed of following steps: first, using breviscapinun saled in market as raw materials, adding 5 to 10 times of water by weight, being heated to 60 to 80 DEG, adding 10 to20 weight percentage of aqueous slkali until the pH value is 5 to 8; second, centrifugating the solution obtained in the step one and discarding the deposition, then the obtained solution going through macroporous resin column, washing and removing, discarding the deep brown part of the first eluant, and then collecting the yellow eluant part; third, the collected eluant is disposed in vacuum concentrator, concentrating until concentration of the scutellarin salt solution is 100 to 200 mg/ml; fourth, adding organic solvent to the concentrated solution obtained in the step three and stirring,depositing, standing and filtering; fifth, washing by using the same organic solvent of the step four for 3 to 6 times, drain, and drying at a temperature of 60 to 80 DEG, then the bulk drug is obtained.