2results about How to "Effective shear" patented technology

The invention provides a preparation method of high-yield icodextrin by combining an ultrasonic field with a single enzyme system. The preparation method comprises the following steps: S1, enzymolysis; s2, performing primary ultrafiltration; s3, ultrasonic hydrolysis; s4, carrying out secondary ultrafiltration; and S5, spray drying. According to the method, firstly, the proportion of dextrin with the molecular weight smaller than 1638 Da in the enzymatic hydrolysate is controlled to be not larger than 7%, the working procedures of recycling macromolecular dextrin and conducting ultrasonic hydrolysis are added, and the yield can reach 80-88%. New amylase does not need to be additionally added in ultrasonic hydrolysis, the hydrolysis time is greatly shortened, the pertinence is high, ultrasonic hydrolysis after enzyme deactivation belongs to physical modification, the reaction degree is conveniently controlled, the generation proportion of dextrin with the molecular weight smaller than 1638 Da is accurately controlled, the production cost is low, the preparation efficiency is high, the consistency of a hydrolysis product and an original product is good, and the method is suitable for industrial production. The generation of 5-hydroxymethylfurfural is completely eradicated, so that the peritoneal dialysis can be continuously carried out.

The invention relates to the technical field of separation and extraction of natural products, in particular to a method for supercritical separation and extraction of astaxanthin, which comprises the following steps: (1) weighing raw material components in parts by weight; (2) mixing a biomass raw material rich in astaxanthin with the functionalized deep-eutectic solvent, and performing physical field enhanced extraction to obtain an extracting solution; (3) filtering the extracting solution through a vibrating membrane, and purifying to obtain a trapped fluid containing astaxanthin; and (4) carrying out supercritical CO2 back extraction on the trapped fluid, separating to obtain an astaxanthin product, and recovering the functional eutectic solvent. According to the method, continuous membrane separation and purification under the eutectic solvent system are realized, the purity of astaxanthin and the proportion of all-trans astaxanthin are maintained while the extraction rate of astaxanthin is increased, the solvent can be recycled after being recovered, and the production cost and waste liquid discharge are greatly reduced. All the raw materials are nontoxic and harmless, no organic solvent is used in the technological process, and good application prospects are achieved.