The present invention provides an intelligence-benefiting type nutritional formula milk powder and a preparation method thereof. According to added amount per kilogram, 300-500 parts of whole milk powder, 100-300 parts of skim milk powder, 100-200 parts of 90 desalted whey powder, 15-40 parts of 70 whey protein powder, 50-90 parts of soybean oil, 5-15 parts of walnut oil, 50-100 parts of lactose,1-3 parts of DHA powder, 2.5-5 parts of ARA powder, 15-40 parts of fructo-oligosaccharide power, 10-20 parts of galactooligosaccharide powder, 0.2-1 part of PS (phosphatidylserine), 0.3-0.8 part of SAsialic acid, 2-7 parts of anhydrous cream, 2-7 parts of child development nutritional packages and 0.3-0.8 part of quadruple lactic acid bacteria (dry addition) are added. The intelligence-benefitingtype nutritional formula milk powder mainly contains eight unique brain-benefiting factors, including choline, taurine, DHA, ARA, the SA sialic acid, the PS (phosphatidylserine), 70 whey protein (milk fat globule membrane) and walnut oil, the speed of cell information transmission of brain nerve cells can be improved, the development of memory and intelligence can be promoted, brain development of children can be helped, and the brain is enabled to be sensitive.