The invention relates to the technical field of wearable sensors, and provides a flexible wearable sensing device based on carbon cloth, a conductive electrode layer and an insulating layer are integrally sewn and assembled to obtain the flexible wearable sensing device, on one hand, product assembly can be completed through simple stacking and sewing, the assembly difficulty is low, and wearing is convenient; and on the other hand, the first electrode layer, the first insulating layer, the second electrode layer, the second insulating layer and the third electrode layer are sequentially stacked from top to bottom, sweat collection is facilitated, and after a certain amount of sweat is absorbed, the first electrode layer, the second electrode layer and the third electrode layer can be automatically conducted with the sweat as a medium, so that the sweat absorption rate is increased. Biomarkers such as glucose, uric acid and tyrosine in sweat can be detected in real time, so that the detection efficiency of the sensing device is improved.