The invention relates to the technical field of micro-needle transdermal delivery, in particular to a method and a device for soft
capsule micro-jet type micro-needle transdermal delivery. The
drug deliver device comprises a soft
capsule which is used for storing
medicine liquid, a micro-jet micro-needle unit which is capable of undergoing mechanical reciprocating vibration, a fixing unit and a controller, wherein one side of the soft
capsule is bonded with and connected to a membrane of the micro-jet micro-needle unit and the other side of the soft capsule is bonded with and connected to the fixing unit; the micro-jet micro-needle unit is connected to the controller by virtue of a
signal line; and the controller is used for controlling a delivery dosage of the
medicine liquid and for controlling the micro-jet micro-needle unit to do mechanical reciprocating vibration before each
drug delivery. With the implementation of the method disclosed by the invention, by precisely controlling the
drug delivery dosage and by controlling the micro-jet micro-needle unit to do mechanical reciprocating vibration before each
drug delivery, various pores can generate in
skin cuticula, which is conducive to the
medicine liquid to permeate
skin epidermis; and in addition, the device disclosed by the invention can achieve change the medicine liquid safely without
pollution, and the device is simple and convenient to operate and use.