2results about How to "Realize discovery" patented technology

The present application relates to a kind of metabolic pathway extension network based on structural feature automatical establishment method, belong to bioinformatics and computational chemistry technical field.The purpose is to solve the problem of existing KEGG database incomplete, annotation lag of metabolite.Method includes: obtaining KEGG skeleton and modified group construction seed library;Through substructure matching and set difference calculation to determine the attribution of derivative;Iterative expansion forms structure association set;Combining stereochemistry rule and mass difference verification screening derivative;Merging KEGG reaction and extended relationship constructs network, and remove redundant path by graph theory method, finally output extended pathway network.The method greatly improves the annotation rate of metabolite pathway, supports in-depth functional analysis of metabolomics data.

The application relates to a method for discovering associated nodes of a springboard node. By analyzing the flow data of the springboard node in a botnet, nodes with highly similar behaviors are discovered from the nodes connected to the springboard node, thereby discovering multiple associated nodes belonging to the same botnet, positioning the C&C server node possibly at the upper level, and providing help for subsequent trace analysis, discovery and prevention of botnet threats. The application can extract important features representing the behaviors of network nodes through analysis of network flow data, input the features into a well-constructed program after pretreatment, complete the discovery of nodes with similar behaviors, and output the results. By drawing a flow curve of the communication between highly suspicious nodes and the springboard node and visually displaying the flow curve, the upper and lower control relationship of the suspicious IP pair is further verified, and the discovery of associated nodes of the same botnet and attack prevention are realized.