The invention discloses an one-line repair device for the inner holes of a blast furnace tuyere-cooler casing. According to the one-line repair device for the inner holes of a blast furnace tuyere-cooler casing, a base is arranged on a blast furnace tuyere platform, a reduction gearbox and a driving motor are arranged on the base, a rotating shaft is connected with the output shaft of the reduction gearbox through a coupler, a conical positioning ring is arranged on one side of the tuyere-cooler casing, the rotating shaft is located on the tuyere-cooler casing and the inner ring of the conical positioning ring through a first annular fixing block, a second annular fixing block and the corresponding rolling bearing, a cross positioning block is arranged on the rotating shaft and located inside the tuyere-cooler casing, a turning tool base, a turning tool and a turning tool rest are arranged on the cross positioning block in sequence, the end face of the turning tool base is a bevel, a tool feeding handle is arranged on the turning tool base, and the turning tool and the turning tool rest are driven by the tool feeding handle to move along the end face of the turning tool base. By using the one-line repair device for the inner holes of a blast furnace tuyere-cooler casing, the blast furnace tuyere-cooler casing can be repaired on line, the positioning accuracy of the center of the blast furnace tuyere can be guaranteed, affect caused by cutting operation on the furnace shell of a blast furnace is avoided, the efficiency of repair on the blast furnace tuyere-cooler casing is improved, and the equipment maintenance cost is reduced.