9results about How to "Reduce potential security risks" patented technology

The present application relates to the field of cell therapy and regenerative medicine, and in particular to a kind of old age adipose tissue-derived mesenchymal stem cells pretreated by MK8722, its preparation method and application.The method comprises the following steps: the old age adipose tissue-derived mesenchymal stem cells are inoculated in culture solution containing MK8722 to carry out in vitro treatment, and first cells are obtained;The culture solution containing MK8722 is removed, and the first cells are washed to obtain second cells;Second cells are cultured using culture solution without MK8722, and the old age adipose tissue-derived mesenchymal stem cells pretreated by MK8722 are obtained.The cells obtained by the method, relative to the old age adipose tissue-derived mesenchymal stem cells without the in vitro treatment, show at least one improvement in proliferation capacity, continuous passage amplification capacity, adipogenic differentiation capacity or chondrogenic differentiation capacity, and can be used to prepare products for treating or alleviating osteoarthritis.

This invention belongs to the field of agricultural biotechnology, specifically relating to a plant constitutive promoter OsSULTR2;2pro and its applications. The nucleotide sequence of the promoter OsSULTR2;2pro is shown in SEQ ID NO.1. The promoter OsSULTR2;2pro of this invention is an endogenous constitutive promoter for rice, capable of driving efficient and stable expression of target genes in plant callus tissue, roots, stems, leaves during vegetative growth, as well as young panicles and seeds, and can replace existing non-plant-derived promoters. It has significant application value in the field of plant genetic engineering and can effectively reduce the potential safety risks of transgenic plants caused by the introduction of exogenous DNA.

The invention discloses a preparation method of inositol nicotinate tablets, and belongs to the technical field of pharmaceutical preparations. By optimizing the existing process and coating components, stable dissolution of drugs is realized, and the method comprises the following steps: dispersing inositol nicotinate in mixed oil to prepare an oil phase, mixing and emulsifying the oil phase and a water phase, performing spray drying to obtain drug milk powder, coating the drug milk powder with modified chitosan, and directly tabletting the coated drug milk powder and auxiliary materials. The preparation method comprises the following steps: uniformly dispersing inositol nicotinate in mixed oil to promote the inositol nicotinate to maintain the uniformity of the drug content in the subsequent process, and adsorbing solid particles on the surfaces of drug-containing oil drops through an emulsification technology to protect the drug components; coating components are reasonably designed, so that fixed-point release of the medicine is realized, the medicine is endowed with anti-pressure ability, and the medicine can be directly tableted; and the coated medicine particles are mixed with auxiliary materials and then are directly tableted, so that the process is simplified, and the coating structure of the medicine particles is protected at the same time. The preparation method can prepare the inositol nicotinate tablet with stable drug dissolution, and the inositol nicotinate tablet is good in taste and small in stimulation to gastric mucosa.

The utility model discloses a detachable silicon steel sheet maintenance frame, which comprises adjusting seats, an auxiliary supporting plate and a supporting frame, the two ends of the auxiliary supporting plate are both provided with the adjusting seats, telescopic rods are movably installed in fixing sleeves on the two sides of the adjusting seats, and the top ends of the two telescopic rods are both fixedly connected with the inner side of the supporting frame. Silicon steel sheets are arranged on the inner sides of the fixing grooves in the inner wall of the supporting frame, threaded columns are arranged at the bottoms of the two sides of the supporting frame, and connecting rods are connected to the portions, above the threaded columns, of the supporting frame through shafts. The modular design is adopted, so that the maintenance frame can be quickly disassembled and assembled, unique connecting devices are adopted between the frames, the stability of frame connection is ensured, potential safety risks caused by unstable connection are reduced, meanwhile, the size of the frame can be adjusted according to actual requirements, and the maintenance cost is reduced. Therefore, the maintenance requirements of silicon steel sheets of different specifications are met, and the applicability of the frame is improved.

The application relates to a smart park security management method, system, device and medium, and belongs to the technical field of smart parks, which comprises the following steps: receiving an access reservation form, identifying the unique identifier of a visitor and a reservation event, and querying historical records in a visit event library according to the unique identifier to calculate initial trust points. Based on the points and the reservation event, a dynamic authorization seed is created, and an access link containing the seed is sent to the visitor end. After entering the park, the initial dynamic access corridor and the permission accompanying unit are generated by using the dynamic authorization seed to guide the visitor to move. When the visitor approaches the target site, the first sub-permission is granted in the adjacent area to allow entry; after entering the target site, the second sub-permission is granted in combination with the historical visit information of the target site and the visitor's own record. When it is detected that the visitor is leaving, the permission recovery instruction is broadcasted to all network edge nodes, the visitor portrait is updated, and the local cache is emptied; the visitor experience is improved, and the security protection capability of the park is strengthened.

This invention discloses a preparation process for a ready-to-use, compounded collagen-poly-L-lactic acid (PLLA) composite filler, comprising: preparing and independently packaging three sterile components: Component A is an injectable coagulated type I collagen solution with a concentration of 30-40 mg / mL; Component B is lyophilized PLA microspheres, with a single bottle containing 150 mg of PLA microspheres; Component C is a sterile reconstitution solvent; injecting a predetermined volume of Component C into a container containing 3-5 mL of Component B, allowing it to stand for 3-10 minutes to obtain a PLA microsphere suspension with a concentration of 30-50 mg / mL; extracting a predetermined volume of Component A and injecting it into a container containing the suspension, then mixing it by reciprocating injection using a three-way stopcock to obtain a homogeneous composite filler mixture. Since the two active components are already independently sealed finished products before compounding, secondary terminal sterilization is not required, thus ensuring the optimal bioactivity and structural integrity of each component from the source, significantly reducing potential safety risks caused by damage to active ingredients.

The invention discloses a safety management system based on an intelligent safety helmet, particularly relates to the field of intelligent safety helmets, and comprises an intelligent safety helmet terminal, an electronic fence module, a cloud data center and a mobile management terminal. According to the invention, through cooperation of the positioning module and the electronic fence, automatic and accurate attendance checking and regional compliance monitoring are realized; the wearing state of the safety helmet is monitored in real time through the human body induction sensor, and uncapping alarm is achieved; all data are uploaded to a cloud data center through the Internet of Things module for unified management and analysis, the problems that traditional manual attendance checking is low in efficiency, personnel positions and states cannot be monitored in real time, safety supervision is passively lagged and the like are solved, and active, intelligent and whole-process safety management of field operation personnel is achieved.

This invention relates to the field of power system security technology, specifically disclosing a grounding wire management operating system based on grounding cabinet monitoring. This system includes a physical sensing layer, an edge computing layer, a blockchain consensus layer, and an application service layer. The physical sensing layer collects grounding wire identity, in-situ status, and electrical parameters; the edge computing layer performs local data processing and event determination; the blockchain consensus layer achieves trusted data storage and cross-domain sharing through smart contracts and distributed ledgers; and the application service layer provides comprehensive asset display, collaborative verification, and risk warning services. Through this architecture, this invention achieves unified management and secure collaboration of grounding wire lifecycle data, improving the level of power grid safety operation and maintenance.

The invention discloses a distributed photovoltaic district energy storage charging and discharging control method based on deep learning, relates to the technical field of power system automation, realizes the conversion of energy storage control from passive response to active defense through situation awareness and dynamic boundary prospective mechanisms, and utilizes a deep learning network in district situation awareness to realize the energy storage control. The power and electric quantity safety boundary of energy storage charging and discharging in the next period is calculated in real time by accurately predicting the area net load power and combining the physical constraint of the area, and the mechanism is used for constructing an operation space dynamically changing along with the future situation, so that any follow-up control decision is limited in the safety space in advance, and the safety boundary of the energy storage charging and discharging in the next period can be calculated in real time. And when the photovoltaic output is predicted to be suddenly increased, the charging power upper limit of energy storage is tightened in advance, and the occurrence of line overload or voltage out-of-limit is actively prevented, so that the probability of potential safety risks is reduced.