The invention provides a biogas slurry sintered brick and a preparation method thereof. The biogas slurry sintered brick is prepared from the following components in percentage by weight: 75-85% of clay, 14-24% of coal gangue and 0.5-2% of biogas slurry. The preparation method of the biogas slurry sintered brick comprises the following steps: carrying out three-stage crushing on clay and coal gangue by adopting a jaw type crusher, a hammer crusher and a fine crushing double roll crushing machine, then adding biogas slurry, stirring by adopting a double-shaft mixer, then aging uniformly mixed materials in an ageing warehouse so that raw materials are fully homogenized, then conveying the homogenized raw material to a forming shop, carrying out extrusion molding by virtue of an extruder to obtain a green body, and finally drying the green body in a tunnel drying room, thus obtaining the biogas slurry sintered brick finished product. The preparation method of the biogas slurry sintered brick has the advantages that the biogas slurry obtained by carrying out anaerobic fermentation on organic ingredients in household garbage in a garbage treatment process and carrying out solid-liquid separation on residual waste is taken as a raw material of the sintered brick, recycling of urban and rural waste is realized, harmless, reduction and recycling treatment of garbage is guaranteed, and brick making cost is greatly reduced, and strength of the sintered brick is improved.