45results about How to "The production process is economical and environmentally friendly" patented technology

The invention provides a monatomic iron nitrogen-doped porous carbon catalyst as well as a preparation method and application thereof. In the catalyst, monatomic iron is taken as an active component, a nitrogen-doped porous carbon material is taken as a carrier, and iron is dispersed on the surface and the interior of the nitrogen-doped porous carbon material in a monatomic form, wherein every 100 wt% of the monatomic iron nitrogen-doped porous carbon catalyst contains 1.0-3.0 wt% of iron and 4.0-9.0 wt% of nitrogen. The invention also provides a method for catalyzing a nitrogen heterocyclic compound with the monatomic iron nitrogen-doped porous carbon catalyst for a dehydrogenation oxidation reaction and application of the monatomic iron nitrogen-doped porous carbon catalyst for catalyzing the nitrogen heterocyclic compound for the dehydrogenation oxidation reaction. The catalyst has an excellent catalytic effect; a product is analyzed by GC-MS (gas chromatography-mass spectrometer) after a catalytic reaction is ended; and an analysis result indicates that no by-product is produced, and the activity of the catalyst is not obviously reduced after the catalyst is used for 5 times.

The invention discloses a preparation method of 16a-hydroxy prednisolone. The preparation method comprises the following steps: dissolving 16a-hydroxy prednisolone acetate into an organic solvent, adding an inert solid carrier adsorbed with strong base as a hydrolysis reaction solid-phase base catalyst, and hydrolyzing 21-acetate to obtain a 16a-hydroxy prednisolone crude product; and carrying out lower alcohol recrystallization on the crude product under the condition of below C4 to obtain a 16a-hydroxy prednisolone competitive product, wherein the refined weight yield is 85% to 90%, and the preparation weight total yield is 75% to 80%. The solid carrier is selected from aluminum oxide, silica gel or calcium carbonate; the base catalyst is selected from sodium carbonate; and the organic solvent is selected from methylbenzene or chloroform. Compared with a traditional method, the method disclosed by the invention is simple and convenient in production operation, impurities generated in traditional production can be greatly reduced, and the total yield for synthesis is greatly improved; compared with the traditional method, the production cost is reduced by 10% to 15%; and a synthetic reaction solvent can be recycled, and industrial production is facilitated.

The invention relates to a making and sterilizing method of a polypropylene plastic infusion bottle, comprising the following steps of: (1) an injection molding and blow molding process: melting medicinal-grade polypropylene granules at high temperature, extruding to make a bottle blank, blowing into a medicine bottle by using clean high-pressure air, wherein a blow molding control mode is a five-speed five-pressure method, and stretching foreblow is carried out before blow molding shaping; (2) a cleaning, filing and sealing process: cleaning the medicine bottle in a pumping way by using clean negative ion air, then filing medicine-containing liquid, controlling the medicine-containing liquid to be filled at the constant temperature of 50-75 DEG C, filling and then sealing a cover; (3) a high-temperature sterilizing process: placing the completely-filled and cover-sealed medicine bottle into a high-pressure sterilizing tank for sterilization, wherein inner pressure is controlled between 0.20 MPa and 0.35 MPa, sterilization temperature is 117-121 DEG C, and sterilization time is 20-12 minutes.

The invention discloses a method for producing high-concentration ethanol by the mixed fermentation of starch and molasses which are used as raw materials. The method comprises the following steps of: adding water to the raw material of starch and stirring to constant volume, liquefying at low temperature and simultaneously fermenting and saccharifying, and then adding the raw material of molasses for mixed fermentation through the batch or continuous flow feeding supplement way. The mixing ratio of the raw materials of starch and molasses is 1:2-8:1 (W/V), the temperature of fermentation is 30-37 DEG C, the time of fermentation lasts for 40-48h, the percentage of ethanol yield is 12.43-16.67% (V/V). The invention changes the traditional single raw material fermentation way, and not only improves the total sugar concentration of the fermented mash, but also reduces the viscosity of starch raw mash and improves the liquidity, so the concentration of ethanol in the fermentation mash is increased, and the raw material utilization rate is improved, and ethanol distillation energy consumption and production cost are decreased, the amount of sewage discharge is reduced, the load of sewage treatment is lowered and the ethanol production process is more economical and environmentally friendly.

The invention provides a method for preparing a 16a-hydroxyl prednisolone product. The method comprises the steps: firstly, subjecting 17a-deshydroxy prednisolone acetate, which serves as a starting raw material, and organic peroxy acid to an epoxidation reaction at 16,17 sites in a first organic solvent, so as to prepare epoxide; subjecting the epoxide and glacial acetic acid to a ring-opening reaction under the catalysis of an acid catalyst in a second organic solvent, so as to prepare 16a,21-diacetoxyl prednisolone; then, dissolving the 16a,21-diacetoxyl prednisolone in a third organic solvent, and hydrolyzing acetate of two positions under the catalysis of a solid-phase alkali catalyst, so as to prepare 16a-hydroxyl prednisolone; finally, subjecting the crude 16a-hydroxyl prednisoloneobtained through solid-phase alkali-catalyzed hydrolysis to heated refluxing, decoloring and recrystallization by low carbon alcohols of C4 or less, thereby obtaining the 16a-hydroxyl prednisolone product. The 16a-hydroxyl prednisolone is prepared by the efficient, environment-friendly and cheap method.

The invention provides a preparation method of 16alpha-hydroxy prednisolone, comprising: subjecting 17alpha-deshydroxy prednisolone acetate as an initial material to 16,17-epoxidation with an organicperoxy acid in a first organic solvent to obtain an epoxide; subjecting the epoxide, in a second organic solvent, to ring-opening reaction with glacial acetic acid under the catalysis of an acid catalyst to obtain 16alpha,21-diacetoxy prednisolone; dissolving 16alpha,21-diacetoxy prednisolone in a third organic solvent, and hydrolyzing acetates in two positions under the catalysis of a solid alkaline catalyst, wherein the solid alkaline catalyst is made by adsorbing sodium carbon or sodium hydroxide to aluminum oxide, silicone or calcium carbonate as a support. The 16alpha-hydroxy prednisoloneis prepared via the method which is efficient, environmentally and fair in cost.

The invention provides a method for preparing a 16a-hydroxyprednisolone product. The method comprises the steps that 17a-dehydroprednisolone is used as a raw material, and firstly the starting material 17a-dehydroprednisolone performs an epoxidation reaction with organic peroxide acid at 16 and 17 sites in a first organic solvent to prepare an epoxy material; then the epoxy material reacts with glacial acetic acid under catalysis of an acid catalyst in a second solvent for loop opening, and thus 16a,21-diacetoxyprednisolone is prepared; 16a,21-diacetoxyprednisolone is dissolved in a third organic solvent, under the catalytic action of a solid-phase base catalyst, acetic ester on the two sites are hydrolyzed, and thus 16a-hydroxyprednisolone is prepared; and finally the 16a-hydroxyprednisolone crude product obtained by solid-phase base-catalyzed hydrolysis is heated and refluxed, decolorized, and recrystallized through low-carbon alcohol below C4, and thus the 16a-hydroxyprednisolone product is obtained. According to the method, 16a-hydroxyprednisolone is prepared in an efficient, environment-friendly and low-cost mode.

The invention relates to a metal patterned transparent photosensitive polyimide film, and a preparation method and application thereof. The metal patterned transparent photosensitive polyimide film comprises a polyimide film and a patterned metal coating attached to the surface of the polyimide film. The polyimide resin has a structure as shown in a formula (I) or a formula (II). The metal patterned transparent photosensitive polyimide film provided by the invention has photochromic property, solubility and excellent flexibility, and can be used for preparing a circuit board of flexible electronic equipment; the adhesion between the metal coating and the polyimide surface is strong, the coating surface is smooth and fine, and the coating thickness is uniform; and the polyimide resin and the metal in the coating on the polyimide resin can be recycled after the polyimide resin is dissolved, so that zero waste and full recycling of the flexible circuit substrate and related circuit boardproducts are truly realized after the service life of an electronic circuit product is ended, and huge economic benefits and environmental protection significance are achieved.

The invention discloses a preparing method for beta-menadione. The preparing method includes the following steps that 1, ceric sulfate is dissolved in a sulfuric acid solution, a ceric sulfate solution is obtained, the beta-methylnaphthalene is dissolved in an organic solvent, and a beta-methylnaphthalene organic solution is obtained; 2, the ceric sulfate solution and the beta-methylnaphthalene organic solution are simultaneously added into a reaction kettle, the mixture is stirred and reacted at the constant temperature, the reaction is ended, cooling crystallization is carried out, and the finished-product beta-menadione is obtained through filtering; 3, the filtered cerous sulfate solution in a liquid phase is separated from the organic solvent, the organic solution is distilled and recycled to be reused, and the cerous sulfate solution is subjected to electrolytic oxidation through a diaphragm to be reused. Chromium oxidation is thoroughly replaced with the preparing method for thebeta-menadione, hexavalent chromium does not exist in the product, the beta-methylnaphthalene is dissolved in an organic phase and reacted, the contact area of the material is larger, the reaction rate is higher, peroxidation of the beta-menadione can be avoided, and the product purity is high.

The invention provides a method for polymer assisted supercritical stripping of transition metal sulfide. The method comprises the following steps: mixing the transition metal sulfide with polyvinylpyrrolidone according to a mass ratio (1-10):1, and placing the obtained mixture in a shearing assisted supercritical device; introducing CO2 into the shearing assisted supercritical device, and carrying out shearing assisted supercritical stripping at a temperature of 32-200 DEG C under a reaction pressure of 8-20 MPa for 10 min to 48 h; and reducing the pressure in the pressure in the shearing assisted supercritical device to half of the reaction pressure or less within 0.1 s after the supercritical stripping, releasing the pressure in the shearing assisted supercritical device to normal pressure, and collecting the above prepared few-layer transition metal sulfide.

The invention discloses a catalyst and a preparation method and application thereof. The catalyst comprises a beta molecular sieve, the catalyst comprises a through-pore channel. The catalyst is provided with a through diffusion pore channel and can be repeatedly utilized; the pore diameter in the range can generate a shape selection effect on the reaction so that the reaction selectivity is improved. Meanwhile, the preparation method of the catalyst is simple.

The invention discloses a high-combination leather fatting agent and a preparing method thereof. The preparing method comprises the following steps that (1) a certain amount of long-chain fatty alcohol and maleic anhydride are added into a reactor, the temperature is raised to 80 DEG C-90 DEG C for esterification reaction, and a product A is obtained; (2) the product A is cooled to 70 DEG C-75 DEGC, a certain quantity of initiator, namely azodiisobutyronitrile is added, a certain amount of monomer acetic acid vinyl ester is dropped in for a polymerization reaction, and a product B is obtained; (3) the product B is heated to 100 DEG C-110 DEG C, a certain amount of long-chain fatty alcohol is added for an esterification reaction, and a product C is obtained; and (4) the product C is cooledto 65 DEG C-70 DEG C, a sodium hydroxide solution with the mass concentration being 30% is used for neutralizing the pH of a reactant to 7.0, then a certain quantity of sulfite aqueous solution is added, a sulfitation reaction is carried out at 80 DEG C-90 DEG C, and the high-combination leather fatting agent is obtained after cooling. The high-combination leather fatting agent and the preparingmethod have the beneficial effects that the process is simple, clean and environment-friendly, the produced product is excellent in acid-resisting stability, fat liquoring effect, filling performance,solvent extraction performance and the like, and the effluent COD content can be reduced.

The invention provides a method for preparing a 16a, 21-diacetoxyprednisolone product. The method comprises that 17a-dehydroxyprednisolone as a raw material and an organic peroxyacid undergo an epoxidation reaction at the 16th and 17th in a first organic solvent to produce an epoxy, the epoxy and glacial acetic acid undergo a ring opening reaction in a second organic solvent in the presence of anacid catalyst to produce a desired product 16a, 21-diacetoxyprednisolone, and the crude 16a, 21-diacetoxyprednisolone is subjected to heating reflux in C1-4 lower alcohol so that the 16a, 21-diacetoxyprednisolone is decolorized and recrystallized and a 16a, 21-diacetoxyprednisolone product is obtained. The method is efficient and environmentally friendly, realizes a low cost and can prepare the 16a-hydroxyprednisolone intermediate 16a, 21-diacetoxyprednisolone.

A preparation method of a 16a-hydroxy prednisolone acetate product includes dissolving 17-dehydroxy prednisone acetate as a raw material in an organic solvent, oxidizing 16 and 17 double bonds by potassium permanganate under acid catalysis to obtain an oxide, dissolving the obtained oxide in an organic solvent, adding acetone, and carrying out acid catalyzed reaction to obtain a protector; dissolving the protector in an organic solvent, adding a reducing agent to reduce ketone at the 11th position, directly adding an acid water solution for hydrolysis and deprotection after the reduction reaction to obtain 16a-hydroxy prednisolone acetate, and subjecting the crude product to decoloration and recrystallization by low-carbon-alcohol heating reflux to obtain the 16a-hydroxy prednisolone acetate product. Although two reaction steps, protection and deprotection, are added, the reaction yield of units in each step is high, the method is simple and convenient to operate, the process is economical and environmentally friendly, and the total synthesis yield is increased remarkably; the preparation cost of the preparation method is 20-25% lower than that of conventional production methods.

Disclosed is a preparation method of 16a-prednisolone hydroxyacetate. The method comprises dissolving 17-prednison dehydroxylated acetate as the raw material into organic solvent, under catalysis of acids, oxidizing 16th and 17th double bonds through potassium permanganate to obtain an oxide, and dissolving the oxide into acetone for acid-catalyzed reaction to obtain a protector; dissolving the protector into organic solvent, adding in reducing agent to reduce 11th ketone, then directly adding in acid aqueous solution for hydrolysis and deprotection to obtain the 16a-prednisolone hydroxyacetate. Although the preparation method of the 16a-prednisolone hydroxyacetate adds the two reaction steps of protection and deprotection, every unit reaction is high in yield, the third and fourth reaction steps can be completed within on pot, so that the production operation can be simple and convenient, the production processes are economical and environmentally friendly, the problems of many side reactions and impurities and difficulty impurity refining of oxidation reaction in traditional production process can be greatly solved, the total synthesizing yield can be greatly increased, and compared with traditional production methods, the preparation method of the 16a-prednisolone hydroxyacetate can reduce the production cost by 20-25%.

The invention relates to the field of ceramics, and discloses a digital guniting decorative ceramic tile and a production device and method thereof. The spraying clock is positioned above the ceramic green brick conveying mechanism; the basic slurry applying mechanism is positioned above the spraying clock; and the movable digital guniting mechanism is positioned above the ceramic green brick conveying mechanism and is positioned at the upstream or downstream of the spraying clock or right above the spraying clock. Decorative slurry is positioned and distributed through the movable digital slurry spraying mechanism, and is combined and matched with basic slurry which is sprayed and distributed, so that a natural and varied decorative slurry layer with various textures can be formed on the surface of a ceramic tile green body, ceramic tile surface decoration means are innovated and enriched, and the ceramic tile surface decoration effect is improved. And the ceramic tile with a new decorative effect can be obtained through subsequent processing. Compared with an existing product, the potential possibility of product pattern design is greatly expanded, the production process is economical and environmentally friendly, and the process controllability is high.