46 results about "Hemoglobin testing" patented technology

A gastrointestinal bleeding noninvasive monitoring system belongs to medical apparatus technical field, wherein a miniature hemoglobin detecting device which enters into gastrointestinal tracts of human body through oral taking can realize 24-hour noninvasive detection of hemoglobin content value in gastrointestinal tracts and can transmit the value outside human body through wireless transmission; a bleeding spot locating device detects position information of the miniature hemoglobin detecting device and transmits detecting results to a record storage device through conducting wire; the record storage device receives gastrointestinal hemoglobin content value transmitted by the miniature hemoglobin detecting device through wireless transmission and stores data of gastrointestinal hemoglobin content value, position information of the miniature hemoglobin detecting device and detecting time information according to predetermined format; a gastrointestinal bleeding diagnosis-analysis system which is arranged outside human body reads and processes the data stored inside the record storage device. The invention can realize 24-hour noninvasive monitoring of gastrointestinal bleeding under normal physiological status of human body.

The invention belongs to the technical field of glycated hemoglobin detection, discloses a glycated hemoglobin and hemoglobin detection kit and a detection method based thereon, and particularly relates to a glycated hemoglobin and hemoglobin detection kit based on boric acid affinity chromatography and a detection method based thereon; the kit comprises reagent R1, reagent R2, reagent R3, reagent R4, and glycated hemoglobin-hemoglobin deposited film; the detection method is specifically a method of detecting glycated hemoglobin and hemoglobin at the same time. Compared with the prior art, the glycated hemoglobin and hemoglobin detection kit and the detection method based thereon have the advantages that by using the kit and detection method, it is possible to shorten the detection time, lower blood taking amount, extend shelf life of the kit, improve detection accuracy, and improve mildness of detection conditions.

The invention provides a multifunctional blood detector. The multifunctional blood detector comprises a central processing unit, a blood collecting bottle energy heating and reagent bottle energy refrigerating stirring arm, a blood detection unit and a remote display device; the central processing unit has properties of an automatic controller and comprises a Bluetooth module, a wireless local area network, an alarming module, a fingerprint confirmation and storage module and a blood collecting needle, blood collecting bottle and reagent bottle holder for storing a blood collecting needle, a blood collecting bottle and a reagent bottle, blood is stirred and mixed to be uniform through the blood collecting bottle energy heating and reagent bottle energy refrigerating stirring arm, the blood detection unit comprises a CRP detection device, a red blood cell counting chamber, a hemoglobin detection device, a laser detection device and a blood reagent strip corresponding item detection position, and the remote display device is used for setting detection items including CRP detection, red cell counting, hemoglobin detection, laser detection and blood reagent strip corresponding item detection.

The invention discloses a hemoglobin analysis method based on a microscopic amplified digital image. The first absorbance alpha1 of the target cell is equal to 1g (the average gray value Gb of the blank area / the average gray value Gc of the target cell area); and obtaining the hemoglobin content CH = of the target cell. The hemoglobin content CH of the target cell is equal to the first absorbance alpha1 * the target cell area STC * the first hemoglobin content correction coefficient CHGB1. By combining the Beer-Lambert law and microscopic magnification digital images, the hemoglobin content of a single target cell can be accurately obtained, so that the visual angle of clinically observing the hemoglobin content goes deep from the total sample hemoglobin content to the hemoglobin content of a single cell level, and the statistical analysis of the single hemoglobin content can be developed. And a deeper layer of valuable information is obtained for clinic. And the whole measurement system is extremely simple, a light path and a liquid path are free from maintenance, the operation and control processes are also extremely simple, and the comprehensive efficiency of hemoglobin detection is greatly improved.

The present invention discloses an opto-acoustic non-invasive hemoglobin detecting device and method capable of realizing temperature compensation and belongs to the technical field of non-invasive detection. According to the detecting method disclosed by the present invention, the concentration of hemoglobin is calculated by virtue of an ultrasonic signal generated by an interaction (an opto-acoustic effect) of multi-wavelength pulse laser and hemoglobin molecules in blood, rather than an optical signal, so that influences from scattered light are avoided, and the method may greatly reduce interference of human tissues and improve the sensitivity as comparison with an existing method; and due to the adoption of a temperature compensation method, the measurement precision is further improved. The device for realizing the detecting method in the present invention mainly includes a laser source module, an ultrasonic transducer, a signal processing circuit, a display, a microcontroller and a temperature sensor. The opto-acoustic non-invasive hemoglobin detecting device and method are suitable for screening the crowd with anemia.

The invention belongs to the technical field of biochemical detection, and particularly relates to a G-6-PD detection kit free from anemia influences and a detection method thereof. The kit comprisesa sample detection device, hemolytic agent dry powder, hemoglobin test paper, a sample adding colorimetric card, G-6-PD test paper and a detection colorimetric card, wherein the sample detection device comprises a sample adding pipe, a first clamping groove and a second clamping groove. According to the kit and the detection method thereof provided by the invention, the anemia degree of a subjectcan be conveniently determined, the sample adding amount can be rapidly determined, the method is used for screening detection of erythrocyte glucose-6-phosphate dehydrogenase (G-6-PD) deficiency, thesample adding amount can be compensated according to hemoglobin test results, the test method is small in blood consumption and flexible and convenient in test, and meanwhile, the accuracy of the detection results is improved.

The invention relates to a piece of test paper for stool examination. The test paper comprises a base plate, a calprotectin detection part, a lactoferrin detection part, a hemoglobin detection part, atransferring detection part, a vibrio cholera detection part, a pH detection part, and a lactose detection part. A plurality of chambers that are spaced and are not communicated are formed on the base plate. In addition, the invention also relates to a kit for stool examination. The kit includes a stool collection device, a stool transfer device, and a stool extraction buffer solution. The test paper and the kit have advantages of small size, light weight, high portability, and simple usage method. Multiple indicators of a sample can be detected once. The detection speed and sensitivity are high; the price is low. The test paper and the kit can be used in a communication hospital widely, thereby enhancing the capability of preliminary detection of diarrhea in a community hospital.

The invention is applicable to the field of medical equipment, and discloses a blood cell analyzer. The device comprises a sampling part, an optical channel reaction tank, an optical detection unit, a hemoglobin detection unit, an impedance counting detection sample preparation unit, an impedance counting detection unit, a first reagent supply device, a second reagent supply device, a diluent supply device, a conveying pipeline assembly and a fluid power device, the sampling part, the optical detection unit, the optical channel reaction tank, the hemoglobin detection unit, the impedance counting detection sample preparation unit, the impedance counting detection unit, the first reagent supply device, the second reagent supply device, the diluent supply device and the fluid power device are connected through the conveying pipeline assembly to form a liquid path system; the average gas consumption of the liquid path system is less than or equal to 2.0 L / min in a detection period of completing hemoglobin detection, impedance counting detection and optical detection, so that the miniaturization and low-cost design of the instrument is realized.

The invention discloses a glycosylated hemoglobin detection reagent. The reagent comprises a reagent R1, a reagent R2 and a reagent R3, the reagent R1 is a latex reagent, the reagent R2 comprises a primary antibody and sensitizing protein, the primary antibody is a mouse anti-human HbA1c monoclonal antibody, the sensitizing protein is protein capable of being directionally combined with a region outside a mouse IgG Fab region on the primary antibody, and the reagent R3 comprises a hemolytic agent. According to the glycosylated hemoglobin detection reagent disclosed by the invention, the sensitizing protein and the primary antibody can be directionally combined, the combination of the primary antibody and glycosylated hemoglobin is not influenced, the detection sensitivity and accuracy of glycosylated hemoglobin are higher, and the detection reagent is convenient to store for a long time and can also keep the activity of the antibody.

The invention relates to the technical field of glycosylated hemoglobin detection, and particularly discloses a glycosylated hemoglobin detection kit which comprises a first reagent and a second reagent. The first reagent comprises latex microspheres, a first buffer solution and a first surfactant; and the second reagent comprises a protein A or a protein G, a glycosylated hemoglobin monoclonal antibody, a second buffer solution and a second surfactant. Through the mode, the kit disclosed by the invention can be stably stored for a long time, and the tedious operation that a monoclonal antibody and a secondary antibody of a reagent in the current market need to be respectively stored and are uniformly mixed for use in the use period is avoided.

The invention discloses an eyelid conjunctiva hemoglobin amount detection method, device and equipment and a storage medium. The method comprises the following steps of: detecting original colour data of to-be-detected eyelid conjunctiva through a colour sensor; correcting the original colour data, and performing illumination removal on the corrected data to obtain target data subjected to illumination removal; and performing table look-up fitting on the target data to obtain the hemoglobin amount of the to-be-detected eyelid conjunctiva. The eyelid conjunctiva hemoglobin amount of a human body can be detected without collecting blood; the detection precision of hemoglobin detection is improved through data correction; the detection time of hemoglobin detection is saved; medical resources of hemoglobin detection are reduced; and the detection speed and efficiency of hemoglobin detection are improved.

The embodiment of the invention discloses a hemoglobin detection method and device and a computer readable storage medium. According to the embodiment of the invention, after a detection image of a to-be-detected user is obtained, the detection image comprises a complete image of at least one nail, the position of the nail in the detection image is identified to obtain a nail area corresponding to the nail, then at least one nail image is extracted from the hand detection image according to the nail area, the nail color of the nail in the nail image is detected to obtain an initial detection result of hemoglobin of the to-be-detected user, and weighted fusion processing is performed on the initial detection result to obtain a hemoglobin detection result of the to-be-detected user; according to the scheme, the convenience of hemoglobin detection can be improved.

A hemoglobin detecting method is executed by a mobile device having a hemoglobin detecting function. The mobile device includes a processor unit, a first light source that generates a first light beam, and a light detecting module that receives a second light beam that is generated when the first light beam travels through an analyte solution and is reflected. The light detecting module generates first to fourth intensity signals according to the second light beam, and the processor unit determines whether the absorption spectrum of the analyte solution matches a target spectrum. If the absorption spectrum of the analyte solution matches the target spectrum, the processor unit generates positive result information; otherwise, the processor unit generates negative result information. The mobile device provides a fast and accurate way to detect blood in a stool solution, which does not require collecting samples of stool or applying any chemical.

The invention discloses a glycosylated hemoglobin detection reagent. The reagent comprises a reagent R1, a reagent R2 and a reagent R3, the R2 reagent comprises a primary antibody and a secondary antibody; the primary antibody is a mouse anti-human HbA1c monoclonal antibody; the first antibody is a glycosylated hemoglobin monoclonal antibody, the second antibody is a goat anti-mouse IgG polyclonalantibody, the R3 reagent comprises a hemolytic agent, R1 is a polystyrene latex reagent, latex microspheres of the R1 reagent are coupled with polylysine, the binding adsorption positions of the surfaces of the latex microspheres and glycosylated hemoglobin are increased through coupling of the polylysine and the latex microspheres, and the binding efficiency is improved. According to the invention, polylysine is coupled to latex microspheres of the reagent R1; through coupling of polylysine and latex microspheres, the binding adsorption positions of the surfaces of the latex microspheres andglycosylated hemoglobin are increased, the binding efficiency of the surfaces of the latex microspheres and the glycosylated hemoglobin can be improved, the detection sensitivity of the glycosylatedhemoglobin detection reagent is obviously improved, the reaction detection time is shortened, and the detection efficiency is improved.

The invention discloses a hemoglobin detection card which is an integrated detection card and mainly comprises three parts, namely a reagent card, a blood sample card and a color developing card, thereagent card is used for storing a detection reagent, and the blood sample card is used for storing a to-be-detected blood sample (namely a to-be-detected hemoglobin sample). The color developing cardis used for realizing reaction color development of the detection reagent and the to-be-detected blood sample. The hemoglobin detection card is simple in structure, sample transfer operation from a hemoglobin collection procedure to a detection and analysis procedure is omitted, and a packaging container is convenient to recycle.

The invention is suitable for the field of medical equipment, and discloses a cell analyzer and a detection method of the cell analyzer. The cell analyzer comprises a sampling part, an optical channel reaction tank, an optical detection unit, a hemoglobin detection unit, an impedance counting detection unit, a first reagent supply device, a second reagent supply device, a diluent supply device, a conveying pipeline assembly and a fluid power device, and the fluid power device comprises a first injector and a second injector. The measuring range of the first injector is smaller than that of the second injector, the second injector is used for driving an optical detection sample to be conveyed into the optical sample preparation pipeline from the optical channel reaction tank, and the first injector is used for providing power for sample suction, sample separation and sample pushing; the second injector is used for providing power for conveying the diluent to the flowing chamber, conveying the diluent to the hemoglobin detection unit, conveying the diluent to the impedance counting detection unit and preparing the sample. According to the invention, the cost and the size of the instrument are greatly reduced.

The invention discloses glycosylated hemoglobin detection test paper and a method for detecting glycosylated hemoglobin by the glycosylated hemoglobin detection test paper. The glycosylated hemoglobindetection test paper comprises a bottom plate, a chromatographic film, a water absorption pad, a partition plate and a cover plate, the chromatography film and the water absorption pad are respectively fixed on the left side and the right side of the top surface of the bottom plate; an optical detection area is arranged on the top surface of the chromatography film; aminophenylboronic acid agarose combined with glycosylated hemoglobin is arranged on the optical detection area; the partition plate is fixed on the top surface of the chromatographic membrane; a hollow part corresponding to the optical detection area is arranged at one end of the partition plate; the inner wall of the hollow part is provided with a high polymer film for sealing and covering the optical detection area, the high polymer film can be dissolved by eluent, the top surface of the partition plate is further provided with a reaction area and an electrode group, and the method for detecting glycosylated hemoglobinby adopting the glycosylated hemoglobin detection test paper comprises the following steps: a) electrochemical detection; b) polymer film dissolution and c) photochemical detection, so that the detection accuracy is high, and the polymer film dissolution speed is controllable.

The invention relates to the technical field of exercise fatigue monitoring, and discloses an exercise fatigue monitoring device based on blood detection. Comprising a monitor, a detection gun, a partition plate, a first chamber, a second chamber, a first telescopic motor, a telescopic rod, a transverse rod, a vertical rod, a testosterone detection module, a cortisol detection module, a creatine kinase detection module, a urea detection module, a rotating motor, a rotating shaft, a placement plate, a containing vessel, a blood sample insertion opening, a third chamber, a conveying belt, a hemoglobin detection module, a fourth chamber and a tooth-shaped button. And a first pressure-sensitive switch and a second pressure-sensitive switch. According to the method, the exercise fatigue degree is comprehensively analyzed by detecting the ratio of testosterone to cortisol, the content of creatine kinase, the content of urea and the content of hemoglobin in serum, monitoring of the fatigue condition after exercise and quantitative display of the exercise fatigue degree index are achieved, and through planned and long-term detection and analysis, the exercise fatigue degree can be accurately determined. And a scientific basis is provided for guidance of exercise training.

The invention relates to a quantitative detection method for creatine and creatinine in whole blood, which comprises the following steps: detecting by using a creatine-creatinine combined detection test strip to obtain hemoglobin detection concentration, creatine detection concentration and creatinine detection concentration of a whole blood sample, and determining a correction coefficient through the hemoglobin detection concentration; the creatine detection concentration and the creatinine detection concentration are corrected, the creatine concentration of the whole blood sample is equal to the creatine detection concentration * the correction coefficient, the creatinine concentration of the whole blood sample is equal to the creatinine detection concentration * the correction coefficient, and the determination method of the correction coefficient comprises the following steps: setting a reference value of the hemoglobin detection concentration; the correction coefficient = (hemoglobin detection concentration / reference value) * correction factor alpha, and if the hemoglobin detection concentration is greater than or equal to the reference value, the correction factor alpha is less than 1; if the hemoglobin detection concentration is smaller than the reference value, the correction factor alpha is larger than 1. According to the method, the influence of endogenous creatine and hemoglobin on the detection of the creatinine concentration of the whole blood sample can be eliminated, and a more accurate detection result can be obtained in a short time.

The invention provides a preparation method of an occult blood critical value quality control material, which comprises the following steps: (1) quality control material container sealing: filling a centrifugal tube with a specification of 0.5 ml by using 0.5-2.0 percent bovine serum albumin, putting into a refrigerator with a temperature of 4 DEG C, sealing for 24 hours, then abandoning liquid in the centrifugal tube and putting the centrifugal tube into a biological safety cabinet to naturally air for standby; (2) critical quality control material preparation: taking a blood routine test specimen of a normal healthy physical examinee, dissolving blood with distilled water according to hemoglobin test results, diluting into 1-2 mg / L, adding a protein stabilizer as well as sodium azide till the final concentration is 2.0-7.0 g / L and 0.2-2.0 g / L respectively and sub-packaging into 0.5 ml sealed centrifugal tube, wherein a solution in each tube is 50-500 ul; and (3) quality control material preservation: preserving the sub-packaged critical value quality control material at a temperature of 4-20 DEG C. The preparation method has the beneficial effects that the preparation is simple, whether a corresponding reagent deteriorates during the processes of circulation, preservation and use or not can be monitored, and the period of validity is long.

The invention brings forward an intelligent hemoglobin detection cloud expert system based on dynamic spectrums. The system is composed of a multi-wavelength pulse-wave data acquisition unit, a dynamic spectrum extraction unit and a cloud hemoglobin detection expert database. By combining dynamic spectrum technology with cloud computing technology, health conditions of users can be monitored in areal-time manner by existing technology. Synthetic judgments can be made in combination with historical data. The shortage of medical resources in the present-day society is alleviated. Detection accuracy and robustness of a model are improved, which lays a foundation for development of medical theories.