112 results about "L-citrulline" patented technology

A non-essential amino acid. In hepatocytes, L-citrulline is synthesized in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. L-citrulline is converted into L-arginine by the enzymes argininosuccinate synthetase and argininosuccinate lyase in the presence of L-aspartate and ATP. Subsequently, L-arginine is converted to nitric oxide by nitric oxide synthase and L-citrulline is regenerated as a by-product . Check for http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=464795&idtype=1 active clinical trials or http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=464795&idtype=1&closed=1 closed clinical trials using this agent. (http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C53406 NCI Thesaurus)