50 results about "Nonlinear spectroscopy" patented technology

This invention provides methods and devices for identifying and / or characterizing interactions involving molecules, including, but not limited to, identifying and / or characterizing interactions involving target molecules and candidate molecules. The present invention provides methods using multidimensional infrared spectrographic techniques, such as four wave mixing and pump-probe techniques, for identifying interactions involving biomolecules and therapeutic candidate molecules, and for characterizing such interactions in terms of their binding coefficients and / or equilibrium constants.

A system and method are disclosed for enhancing audio signals by nonlinear spectral operations. Successive portions of the audio signal are processed using a subband filter bank. A nonlinear modification is applied to the output of the subband filter bank for each successive portion of the audio signal to generate a modified subband filter bank output for each successive portion. The modified subband filter bank output for each successive portion is processed using an appropriate synthesis subband filter bank to construct a modified time-domain audio signal. High modulation frequency portions of the audio signal may be emphasized or de-emphasized, as desired. The modification may be applied within one or more frequency bands.

A method and system for delivering laser pulses achieves the delivery of high quality laser pulses at the location of an application. The method includes the steps of: generating laser pulses, amplifying the laser pulses, temporally stretching the amplified laser pulses, and propagating the amplified laser pulses through an optical delivery fiber of desired length, wherein the laser pulses are temporally compressed in the optical delivery fiber and wherein the laser pulses undergo nonlinear spectral broadening in the optical delivery fiber.

A self-similarity mode locking optical fiber femtosecond laser device based on spectrum compression and amplification is composed of an optical fiber coupling output laser diode, a wavelength division multiplexing coupler, a ytterbium-mixed monomode optical fiber, an optical fiber frequency spectrum filter, a monomode optical fiber, an optical fiber collimator, a quarter-wave plate, a half-wave plate, a polarization splitting prism, a 45-degree reflector, a grating and an optical fiber isolator. Spectrum is compressed by using the self-phase modulation generated when negative chirp pulses are amplified in the ytterbium-mixed monomode optical fiber, narrow-band chirp-free picosecond pulses are formed, the optical fiber frequency spectrum filter is used for eliminating residual side lobes in nonlinear spectrum compression, self-similarity evolution is completed in the monomode optical fiber, broadband linear chirp parabola pulses are output directly, and Fourier transformation extremity femtosecond lasers are output after chirps are eliminated. The self-similarity mode locking optical fiber femtosecond laser device is high in efficiency, large in self-similarity evolution spectrum widening amount, capable of obtaining Fourier transformation extremity femtosecond laser pulses high in energy and narrow in pulse width, compact in structure and easy to operate.