The invention discloses a fixing device for cosmetic bag production. The fixing device for cosmetic bag production comprises a workbench, wherein the upper side of the workbench is rotationally connected with two mutually parallel lead screws, the front side lead screw is connected with a motor, the right end of the front side lead screw meshes with a transmission wheel through a gear, a chain wheel is coaxially arranged on the transmission wheel, the transmission wheel is connected with the rear side lead screw through a chain, sliding blocks are rotationally connected to the lead screws and slidably connected to the interiors of sliding grooves of the workbench, folding plates are arranged at the left ends and the right ends of the upper sides of the sliding grooves, the other ends of the folding plates are fixed to the sliding blocks, the lead screws are driven by the motor to rotate so as to drive the sliding blocks to move, and the folding plates protect a rotating assembly. According to the fixing device for cosmetic bag production, through the arrangement of turning plates and a first top plate, a bag is turned over, and meanwhile, through the arrangement of second sliding grooves and pressing wheels, the outer surface of the bag is pressed to release internal stress, and meanwhile, the bag is supported through the first movable top plate and a second movable top plate, and the bag is convenient to take down in the later period.