The invention discloses an automatic active early warning system for highway rescue. The automatic active early warning system comprises an early warning vehicle and a remote control device, wherein the remote control device is connected with the early warning vehicle through wireless signals, the early warning vehicle comprises an underpan, the lower part of the underpan is provided with a plurality of rolling wheels, the rolling wheels are connected with a motor arranged on the underpan, and a control unit is arranged on the underpan and is respectively connected with a power supply, a warning lamp, a warning plate, a distance measurement sensor, an alarm, an automatic parking device, an automatic tracking sensor and a first singlechip wireless transceiver which are arranged on the underpan. The early warning system can warn drivers and rescue people in the first time, the warning effect is obvious, the safety performance is good, the automation degree is high, the operation is simple, and the occurrence of secondary accidents injuring the rescue personnel can be effectively prevented.