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36results about How to "High development and application value" patented technology

Milky tea powder and preparing method thereof

The invention discloses milk-tea powder as well as a preparation method thereof, which is prepared by fresh milk, white sugar, non-dairy creamer, green brick tea, and solid essence powder according to a certain proportion. The preparation method comprises the following steps: A. comminution: the brick tea is comminuted into superfine tea powder; B. mixture: a proper amount of the fresh milk is taken and heated by a plate heat exchanger, via a water-powder mixer, the tea powder, the white sugar, the non-dairy creamer, and the solid essence powder are added and stirred circularly, and the rest raw milk is added; C. sterilization; D. concentration: the material is sterilized and concentrated by a double effect falling film vacuum evaporator to obtain the concentrated material; E. spray drying: the concentrated material is sprayed and dried by a high pressure pump; F. redrying by a fluidized bed to obtain the milk-tea powder. The milk-tea powder has reasonable formula, convenient drinking, easy method and simple technique, thereby minimizing the energy consumption in the milk-tea processing technique, shortening the productive time with enhanced stability of the milk-tea quality, and increasing the utility ratio of the tea in the milk-tea manufacturing process without waste and pollution.
Owner:NEW HOPE DAIRY HLDG

High-iron, high-manganese and high-ammonia nitrogen underground water integral treatment apparatus and method thereof

The invention relates to a high-iron, high-manganese and high-ammonia nitrogen underground water integral treatment apparatus and a method thereof, and belongs to the field of water supply purification. The problem of unable effective synergistic removal of iron, manganese and ammonia nitrogen of high-ammonia nitrogen underground water treatment, and the problems of low iron and manganese removal rate, long treatment process, long running cycle, complex running management and large investment due to unstable manganese removal when the ammonia nitrogen content is high are solved in the invention. The apparatus is composed of an underground water aeration tank, an integral two-stage filtration pot, an inlet water submersible pump, a filtration pot water inlet pipe, a filtration pot water outlet pipe, a backwashing pipe, a backwashing pump and a clear water tank. The method comprises the following steps: 1, starting a filter column; 2, culturing the filter column; and 3, carrying out an underground water treatment stage to complete efficient and stable purifying treatment of the high-iron, high-manganese and high-ammonia nitrogen underground water. The apparatus and the method have the advantages of simple process flow, small occupied area, strong impact resistance, low running cost, and high water yield; and the apparatus and the method allow the iron content, the manganese content and the ammonia nitrogen content of outlet water to be respectively reduced to 0.1mg / L, 0.05mg / L and 0.1mg / L or below.
Owner:BEIJING UNIV OF TECH

Technology for processing solid nutrient soymilk tea

The invention discloses a technology for processing solid nutrient soymilk tea, comprising the steps of mixing raw materials, granulating, drying, mixing, filling, assembling and the like. By means of products which are produced by using the technology, the absorption and utilization rates of the nutritional components such as soybean isoflavone, dietary fiber and vegetable protein in the soybeans by the human body are increased; and the products have the advantages of good flavor, good instant solubility, convenience for drinking and carrying, light weight, small size, reasonable processing technology, high degree of mechanization and higher development and application values.
Owner:SHANDONG DOUGONGFANG FOOD

Method for comprehensively extracting and purifying oxidation-resistant active ingredient in sugarcane toppers or slag

InactiveCN101530193AThe method is scientific and efficientStrong targetingFood preparationHigh concentrationSlag
The invention discloses a method for comprehensively extracting and purifying anthocyanin and general flavone which does not comprise the anthocyanin in sugarcane toppers or slag. The method comprises the steps of firstly extracting the sugarcane toppers or slag by an organic solvent, concentrating the extract and passing the extract through a chromatographic column filled with a macro-porous adsorptive resin, removing water-soluble impurities such as glucide by a gradient elution method, respectively collecting the ethanol eluent with a low concentration and the ethanol eluent with a high concentration to obtain two ingredients of the anthocyanin and the general flavone which does not comprise the anthocyanin, and respectively enriching and purifying the ingredients of the anthocyanin and the general flavone which does not comprise the anthocyanin by a solvent extraction method and an acid and alkali treatment method so as to obtain the anthocyanin and the general flavone which does not comprise the anthocyanin. Compared with the reported methods for extraction and separation of similar ingredients, the method of the invention can not only completely extract two main oxidation-resistant ingredients in the sugarcane toppers or slag, also the reagents consumed in the technological process can be recycled. The method has low production cost, high purity and mature technology, and is easily controlled and in favour of industrial production.
Owner:SICHUAN UNIV

Application of scutellarin to treatment of microglia-mediated diseases

The invention relates to application of scutellarin shown as a formula I to the treatment of microglia-mediated diseases. Typically, the invention relates to the application of the scutellarin to the preparation of medicaments for treating and / or preventing the microglia-mediated diseases, in particular to the application of the scutellarin to the preparation of medicaments for treating and / or preventing microglia-mediated neurotoxicity-caused neural immune inflammatory diseases. The scutellarin has the novel functions of remarkably inhibiting the generation of inflammatory mediators, namely nitric oxide (NO), a tumor necrosis factor (TNF) alpha and interleukin (IL)-1beta which activate microglia, inhibiting the expression of inducible nitric oxide synthase (iNOS), TNF alpha and IL-1beta messenger ribonucleic acid (mRNA), inhibiting the generation of reactive oxygen species in the microglia, reducing the activation of nuclear factor (NF)-kappa B and remarkably alleviating the cytotoxicity of the microglia to neurons. Therefore, the scutellarin can be applied to the prevention and treatment of brain immune inflammatory related diseases such as Parkinson's disease and the like. The formula I is shown in the specifications.
Owner:TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE

Method for preparing temperature rise elastic force automatic compensation titanium spring of pneumatic friction clutch brake

InactiveCN102303211AFast brakingGuaranteed instant clutchTitaniumTitanium alloy
The invention relates to a method for preparing a temperature rise elastic force automatic compensation titanium spring of a pneumatic friction clutch brake. The method comprises the following steps of: 1, selecting and determining the range of phase transformation points of a titanium alloy; 2, measuring the phase transformation points of the selected titanium alloy material; 3, cold drawing the titanium alloy for filamentization; 4, winding to form a spring; 5, cutting, and processing the two ends of the spring to form planes; 6, putting the titanium spring into a furnace, heating, and preserving heat; and 7, cooling. The method has a simple preparing process, and the titanium spring is convenient to mount and use. When the pneumatic friction clutch brake is designed and manufactured, heat dissipation area and heat dissipation openings are not required to be increased specially. In the summer which has an extremely low heat dissipation effect and is extremely hot, instant clutching and quick braking of a clutch can be ensured. Therefore, the method is extremely high in development value and application value during actual application.
Owner:SHANDONG UNIV

Arylbenzofuran derivative with alpha-glucosidase inhibitory activity

The invention belongs to the field of medical chemistry and relates to an arylbenzofuran derivative with alpha-glucosidase inhibitory activity as well as a preparation method and application of the derivative in a composition, a drug and a health-care product that are used for preventing and / or treating type 2 diabetes mellitus. In the invention, a series of arylbenzofuran compounds are designed and synthesized by taking a mother nucleus structure of an arylbenzofuran ring as a synthesis target through a chemical synthesis method. The biological activity and the structure-function relationshiprelated to the arylbenzofuran derivative are deeply evaluated and discussed by applying a computer-aided drug design method, combining in vitro and in vivo pharmacological activity evaluation experiments and taking alpha-glucosidase as a target protein, so that a solid material basis is provided for discovering a lead compound of an alpha-glucosidase inhibitor drug with high efficiency and low toxicity.
Owner:ANHUI UNIVERSITY OF TECHNOLOGY AND SCIENCE

New application of ascorbic acid

The invention relates to new application of ascorbic acid, that is, the ascorbic acid has the anti-ageing function by a cell reprogramming mechanism, so as to provide direct and powerful experimental basis and theory basis for the anti-ageing application of the ascorbic acid; therefore, the invention has strong scientificalness and innovativeness and has high development and application value.
Owner:GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACAD OF SCI

Continuous c-di-AMP production method

The present invention belongs to the technical field of genetic engineering and enzyme engineering, and particularly relates to a method for continuous production of c-di-AMP by using immobilized DisA protein. The method comprises: 1, DisA gene transformation, wherein DisA gene and cbm gene are fused through gene engineering to construct a recombinant plasmid vector; 2, recombinant plasmid transformation and CBM-DAC fusion protein expression; 3, one-step DAC enzyme purification and immobilization; 4, continuous c-di-AMP production; and 5, reaction product separation concentration and purification. According to the present invention, the characteristic that the CBM domain is combined with cellulose and no hydrolysis exists is specifically utilized, the process is mature, the production cost is low, the environmental protection is provided, the types of the prepared DAC enzyme are diversified, the sources are wide, the concentration and the purity are high, the enzymatic reaction efficiency is high, and the good development and application value is provided.
Owner:HENAN AGRICULTURAL UNIVERSITY

Application of tanshinone I to treatment of microglia-mediated disease

The invention relates to an application of tanshinone I shown in a formula I to the treatment of a microglia-mediated disease, in particular to an application of tanshinone I to the preparation of a medicament for treating and / or preventing the microglia-mediated disease, in particular to an application of tanshinone I to preparation of a medicament for treating and / or preventing psychoneuroimmunology chronic inflammatory diseases caused by microglia-mediated neurotoxic effects. The tanshinone I provided by the invention has the novel functions of remarkably suppressing microglia cell-activated and induced cell death, suppressing the generation and expression of inflammatory mediators, i.e., NO and TNF alpha of microglia cells, and remarkably lowering the cell toxicity of activated microglia cells on neurons, the tanshinone I can be applied to prevention and treatment of brain immune inflammation-related diseases such as Alzheimer's disease, Parkinson's disease, and the like. The formula I is shown in the specifications.
Owner:TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE

Method for extracting natural food antioxidant from areca catechu leaves

The present invention belongs to the technical field of food additives and provides a method for extracting a natural food antioxidant from areca catechu leaves. The method is as follows: the areca catechu leaves are washed, the washed areca catechu leaves are dried, the dried areca catechu leaves are crushed, then the crushed areca catechu leaves are mixed with acid substances, alcohol substancesand water, the mixture is added into an extraction tank for ultrasonic-assisted extraction to obtain an extract, then the extract is concentrated, and the concentrated extract is infrared-ray dried to obtain the natural food antioxidant. Compared with the traditional method, the extraction method is short in time and high in extraction rate. The obtained polyphenolic compounds are all derived from natural ingredients, good in antioxidant performance, good in medical performance, and free of toxic and side effects. Besides, the raw materials in the whole extraction method are easily available,the processes are simple, the costs are relatively low, pollution is small, and the method has certain development and application value and can be popularized and applied.
Owner:CHENDU NEW KELI CHEM SCI CO LTD

Manufacturing method of power drive belt that can generate power output and drive equipment

The invention relates to a manufacturing method of a power drive belt that can self-generate power output and drive equipment, which comprises the following steps of: choosing and determining the chemical compositions of TiNi alloy; cold-drawing the TiNi alloy into threads or cold-rolling the TiNi alloy into strips; cutting off TiNi alloy threads or strips; connecting both ends of the TiNi alloy threads or strips cut off to form a TiNi alloy power drive belt; putting the TiNi alloy power drive belt into a heating furnace for heating and preserving temperature; and cooling the belt. The invention is simple in manufacturing technology and low in manufacturing price. When in use, the alloy power drive belt is only required to be installed on driven equipment and two belt wheels in hot water, and can drive all machinery equipment by fully using terrestrial heat and low-temperature hot water discharged by enterprises. At a place with terrestrial heat and low-temperature hot water, the alloy power drive belt can combine with a solar water heater and can replace an internal combustion engine and a motor completely. Therefore, the invention has relatively high development and application value.
Owner:SHANDONG UNIV

Manufacturing method of automatic paddle blade dispensing with power drive

The invention relates to a manufacturing method of an automatic paddle blade dispensing with power drive, comprising the following steps: 1) determining chemical composition of TiNi alloy; 2) cold-rolling the TiNi alloy to strips; 3) cutting the cold-rolled strip into TiNi alloy strips; 4) heating the cut TiNi alloy strips in a heating furnace and preserving heat; 5) after heat preservation, taking the TiNi alloy strips out of the heating furnace and water-cooling the TiNi alloy strips to the room temperature; 6) determining internal sizes of constraint copper pipes or aluminum pipes; 7) rolling the water-cooled TiNi alloy strips into cylinders and loading the cylinders into the constraint copper pipes or aluminum pipes; 8) heating the TiNi alloy strips in the constraint copper pipes or aluminum pipes in the heating furnace and preserving the heat; 9) after coming up to the holding time, taking the TiNi alloy strips in the constraint copper pipes or aluminum pipes out and cooling the TiNi alloy strips to the room temperature. Compared with the manufacturing processes of internal-combustion engines, the manufacturing processes of the method are simple; the manufacturing price is low; the TiNi alloy blades manufactured by the method can be used for all the motor vessels.
Owner:SHANDONG UNIV

Remote control intelligent trolley system based on bluetooth technology

The invention provides a remote control intelligent trolley system based on a bluetooth technology. The system comprises an intelligent trolley, a remote controller or / and a mobile terminal, when theremote controller and the intelligent trolley establish communication based on the bluetooth technology, the remote controller can carry out remote control on the intelligent trolley through keys or voice, and when the mobile terminal establishes communication with the intelligent trolley based on the bluetooth technology, the mobile terminal can carry out remote control on the intelligent trolleyby simulating and generating the keys of the remote controller and the control function realized by the keys, or carry out remote control on the intelligent trolley by simulating and generating the voice of the remote controller and the control function realized by the voice. According to the system, during implementation, under the condition that the cost is not increased, a flexible operation mode of a user is provided, and different requirements can be met.
Owner:温州智龙智能科技有限公司

Arylbenzofuran derivatives with α-glucosidase inhibitory activity

The invention belongs to the field of medicinal chemistry, and relates to an arylbenzofuran derivative with α-glucosidase inhibitory activity and a preparation method, and a composition and a medicine for preventing and / or treating type 2 diabetes of the derivative , Application on health products. The present invention designs and synthesizes a series of aryl benzofuran compounds by means of a chemical synthesis method, taking the core structure of the aryl benzofuran ring as the synthesis target. Using the method of computer-aided drug design, combined with in vivo and in vitro pharmacological activity evaluation experiments, taking α-glucosidase as the target protein, the relevant biological activity and structure-activity relationship were evaluated and discussed in depth, in order to find high-efficiency and low-toxicity α-glucosidase. ‑Glucosidase inhibitor drug lead compounds provide a solid material basis.
Owner:ANHUI POLYTECHNIC UNIV

Quantum dot labeled antibody multicomponent non-competitive homogeneous immunoassay method for small-molecule organic matter

InactiveCN102495205BStrong specificityExcellent fluorescence performance of quantum dotsFluorescence/phosphorescencePhosphateUltraviolet lights
The invention discloses a quantum dot labeled antibody multicomponent non-competitive homogeneous immunoassay method for a small-molecule organic matter, and relates to a quantum dot labeled antibody multicomponent non-competitive homogeneous immunoassay technology for the small-molecule organic matter. Fluorescent light emits high-efficiency water-soluble quantum dots with different wavelengths to label antibodies resisting different target analytes. Different quantum dot labeled antibodies are dispersed into a phosphate buffering solution, and a sample solution containing the corresponding target analytes is added into the phosphate buffering solution and uniformly mixed with the phosphate buffering solution, so that non-competitive homogeneous immunoassay reaction is performed; respective labeled samples, samples and a blank contrast system which are subjected to reaction and balanced are directly subjected to fluorescent scanning or multi-wavelength detection under the excitation of ultraviolet light with the same wavelength; and the high-sensitivity quantum dot labeled antibody multicomponent non-competitive homogeneous immunoassay technology for quickly detecting various target small-molecule organic matters is constructed according to a rule that a ratio of the characteristic fluorescent light intensity of the blank contrast system to the characteristic fluorescent light intensity of a sample system is in direct proportion to the concentration of the corresponding target analytes in a certain range.
Owner:YANGZHOU UNIV

Purification method of beta-glucuronidase

The invention discloses a purification method of beta-glucuronidase. The method comprises the steps of taking adult snails, cutting off shells, taking down soft parts, cutting off body walls in a culture dish, pulling out digestive glands, and putting digestive glands into a culture dish; puncturing the digestive glands by using a needle head, collecting the flowing viscous liquid and the digestive glands respectively, centrifuging under a certain condition to remove precipitates, combining supernate, and filtering by using a filter membrane to obtain a crude extract containing beta-glucuronidase; enabling the crude extract to pass through a DEAE ion exchange column for linear gradient elution, firstly determining the enzyme activity of the obtained eluents, then combining the eluents withrelatively high enzyme activity to obtain a beta-glucuronidase purified product; adding a preservative and an antioxidant; and performing low-temperature preservation. According to the invention, thepurification method is simple and feasible; the active material (snail) is rich in source, low in price, easy to obtain and short in period; and the purified beta-glucuronidase is high in activity, good in stability and high in recovery rate, can completely meet the requirements of an in-vitro diagnostic kit, and has relatively high development and application values.
Owner:ZHENGZHOU IMMUNO BIOTECH

Canarium album granule with hypolipidemic and hypoglycemic effects and preparation process of same

The invention relates to a Canarium album functional food with hypolipidemic and hypoglycemic effects and a preparation process of same. The functional food is made from Canarium album and balsam pear as major materials, in addition of medicinal and edible natural herbs which are approved by the country; and the nutrients and active factors are extracted from the materials and processed by the conventional granulation process to make solid granules. The functional food is made from the following raw materials in parts by weight: 3 to 18 parts of Canarium album, 1 to 10 parts of balsam pear, 1to 5 parts of Astragalus membranaceus, 0.5 to 2 parts of Salvia miltiorrhiza, 0.5 to 2 parts of Rhizoma ligustici Chuanxiong, 0.3 to 1 part of Chicken's gizzard-membrane, 1 to 5 parts of Dioscorea opposita, 1 to 5 parts of hawthorn, 1 to 5 parts of Lycium chinesis, 0.5 to 2 parts of Rhizoma Polygonati and 2 to 10 parts of mulberry leaves. The raw materials are nontoxic to human body and no non-edible chemical is added during the preparation process, so that the functional food is harmless to human body and is green and safe. The product has the effects of promoting blood flow, removing blood stasis, invigorating spleen, promoting digestion, moistening the lung, promoting production of body fluids, nourishing yin, removing heat, soothing throat and liver, tonifying the kidney, reducing lipid level and reducing body weight, can improve metabolic functions of human body and regulate blood lipid level, blood sugar level and blood pressure, has calcium supplement and hematinic functions, is applied to food therapy for health preservation, can be used for preventing and treating type II diabetes mellitus and cardiovascular diseases, and can be further developed to anti-diabetic Chinese medicines. Therefore, the invention has high development and application values.
Owner:福州市鼓楼区大特生物技术有限公司

Method for preparing phase-change copper alloy inner and outer radiating integrated piece for high-power light-emitting diode (LED)

The invention relates to a method for preparing a martensite phase transformation copper alloy inner and outer radiating integrated piece for a high-power light-emitting diode (LED). The method comprises the following steps of: 1, determining a martensite phase transformation of a copper alloy; 2, determining a geometric shape of a radiating piece, wherein the end of the radiating piece contacting a chip is named a radiating pad end, and the other end of the radiating piece is positioned outside the package and is named a radiator end; 3, machining the radiating piece for forming; 4, putting the radiating piece into a thermal treatment furnace, heating and performing heat preservation; 5, taking the radiating piece out and performing second-stage heat preservation; 6, taking the radiating piece out and cooling; and 7, performing surface treatment on the radiating piece. The preparation process is simple, the integrated piece is low in manufacturing cost and convenient to use, functions of a radiating pad, a printed board, a radiator and other devices in the prior art can be integrated, and the radiating path and thermal resistance are greatly reduced. Moreover, each gram of alloy can absorb 7 to 9 joules of heat, the radiating capacity is greatly improved, the service life is prolonged, and the luminous efficiency is improved. Therefore, the method is high in development and application value in practical application.
Owner:SHANDONG UNIV

Method for preparing phase-change copper alloy inner and outer radiating integrated piece for high-power light-emitting diode (LED)

The invention relates to a method for preparing a martensite phase transformation copper alloy inner and outer radiating integrated piece for a high-power light-emitting diode (LED). The method comprises the following steps of: 1, determining a martensite phase transformation of a copper alloy; 2, determining a geometric shape of a radiating piece, wherein the end of the radiating piece contacting a chip is named a radiating pad end, and the other end of the radiating piece is positioned outside the package and is named a radiator end; 3, machining the radiating piece for forming; 4, putting the radiating piece into a thermal treatment furnace, heating and performing heat preservation; 5, taking the radiating piece out and performing second-stage heat preservation; 6, taking the radiating piece out and cooling; and 7, performing surface treatment on the radiating piece. The preparation process is simple, the integrated piece is low in manufacturing cost and convenient to use, functions of a radiating pad, a printed board, a radiator and other devices in the prior art can be integrated, and the radiating path and thermal resistance are greatly reduced. Moreover, each gram of alloy can absorb 7 to 9 joules of heat, the radiating capacity is greatly improved, the service life is prolonged, and the luminous efficiency is improved. Therefore, the method is high in development and application value in practical application.
Owner:SHANDONG UNIV

Method for comprehensively extracting and purifying oxidation-resistant active ingredient in sugarcane shoots or slag

InactiveCN101530193BThe method is scientific and efficientStrong targetingOrganic chemistryFood preparationHigh concentrationSlag
The invention discloses a method for comprehensively extracting and purifying general flavone and anthocyanin in sugarcane toppers or slag. The method comprises the steps of firstly extracting the sugarcane toppers or slag by an organic solvent, concentrating the extract and passing the extract through a chromatographic column filled with a macro-porous adsorptive resin, removing water-soluble impurities such as glucide by a gradient elution method, respectively collecting the ethanol eluent with a high concentration and the ethanol eluent with a low concentration to obtain two sites of the general flavone and anthocyanin, and respectively enriching and purifying the sites of the general flavone and anthocyanin by an acid and alkali treatment method and a solvent extraction method so as to obtain the general flavone and anthocyanin. Compared with the reported methods for extraction and separation of similar ingredients, the method of the invention can not only completely extract two main oxidation-resistant ingredients in the sugarcane toppers or slag, also the reagents consumed in the technological process can be recycled. The method has low production cost, high purity and mature technology, and is easily controlled and in favour of industrial production.
Owner:SICHUAN UNIV

An integrated treatment device and method for groundwater with high iron, high manganese and high ammonia nitrogen

The invention relates to a high-iron, high-manganese and high-ammonia nitrogen underground water integral treatment apparatus and a method thereof, and belongs to the field of water supply purification. The problem of unable effective synergistic removal of iron, manganese and ammonia nitrogen of high-ammonia nitrogen underground water treatment, and the problems of low iron and manganese removal rate, long treatment process, long running cycle, complex running management and large investment due to unstable manganese removal when the ammonia nitrogen content is high are solved in the invention. The apparatus is composed of an underground water aeration tank, an integral two-stage filtration pot, an inlet water submersible pump, a filtration pot water inlet pipe, a filtration pot water outlet pipe, a backwashing pipe, a backwashing pump and a clear water tank. The method comprises the following steps: 1, starting a filter column; 2, culturing the filter column; and 3, carrying out an underground water treatment stage to complete efficient and stable purifying treatment of the high-iron, high-manganese and high-ammonia nitrogen underground water. The apparatus and the method have the advantages of simple process flow, small occupied area, strong impact resistance, low running cost, and high water yield; and the apparatus and the method allow the iron content, the manganese content and the ammonia nitrogen content of outlet water to be respectively reduced to 0.1mg / L, 0.05mg / L and 0.1mg / L or below.
Owner:BEIJING UNIV OF TECH
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