The invention relates to a manufacturing method of a projection screen panel. The manufacturing method of the projection screen panel comprises the following steps that (1) polycarbonate, acrylic resin and organic silicon are uniformly mixed, dried for six hours and stirred at the high speed, so that a macromolecule raw material is obtained; (2) solvent red, carbon black, phthalo blue, a dispersing agent, an antioxidant and polycarbonate are taken and stirred at the low speed, the heating is conducted to enable the temperature to range from 260 DEG C to 280 DEG C, and pelletization is conducted, so that colored nano particles are obtained; and (3) the macromolecule raw material obtained in the step (1) and the colored nano particles obtained in the step (2) are taken, stirred and added toan extruder set, and the transmission screen panel is obtained through extrusion, specifically, the thickness of the transmission screen panel ranges from 1.5mm to 2mm. The projection screen panel which is manufactured according to the manufacturing method of the projection screen panel can achieve the physical seamless purpose, the size of a screen can be set at random, the screen does not need to be spliced, and the projection screen is high in resolution, high in projection color rendition degree, high in close-range watching definition, low in grey degree and high in light degree, is freeof blue light, is not dazzling and solves the problem that the resolution of the projection screen is poor.