The invention belongs to the technical field of medical skin disinfectants, and discloses a medical skin disinfectant. The medical skin disinfectant is prepared through the following steps of weighing 5g of purslane, 5g of common cnidium fruit, 5g of clove, 5g of anise, 5g of dried ginger, 3g of toad, 3g of white peony root, 3g of honeysuckle flower and 3g of saffron crocus, mixing, adding water into the mixture, wherein the weight of added water is 5 to 8 times that of the mixture, carrying out immersion for 0.5 hours, heating to boil the mixture for 1 hour, filtering, adding water into the decoction dregs obtained by the previous step, wherein the weight of added water is 3 to 5 times that of the decoction dregs, boiling for 1 hour, filtering, merging the filtrate, adding sterile water into the filtrate to a volume of 1000ml, adding 5g of polyvinyl chloride nonylphenol ether and 10g of glycerol into the solution obtained by the previous step, stirring uniformly, adding 2g of effective iodine and 2g of metronidazole into the mixture obtained by the previous step, and stirring uniformly. The medical skin disinfectant has the advantages that iodine content is low so that the stimulation of iodine on human body skin is reduced; iodine removal is avoided so that a nurse work load is reduced; the medical skin disinfectant can act on skin in the long term so that sterilization and disinfection effects are improved and secondary infection caused by bacteria is avoided; and the medical skin disinfectant is added with traditional Chinese medicines so that sterilization and disinfection effects are improved further and stimulation effects on skin are reduced.