The invention belongs to the technical field of cosmetics, and discloses a moisturizing and soothing spray. The moisturizing and soothing spray comprises a group A preparation water, p-hydroxyacetophenone, a group B preparation 1, 2-pentanediol, a glycerol composition and a butanediol composition. A preparation method of the preparation comprises the following steps: S1, adding the group A preparation into a water phase pot, performing stirring and heating to 90 DEG C until no particles are dissolved, and performing sterilizing at constant temperature for 10 minutes; S2, after sterilization of the group A preparation is completed, starting the cooling; S3, performing cooling to 45 DEG C, adding the preparation B, and uniformly performing stirring; S4, performing cooling to 38 DEG C, performing filtering with 400-mesh filter cloth, and performing discharging. The moisturizing and soothing spray is used for after-sun first aid, thermal spring water and glacier water adopted in the formula have the effects of enhancing skin tolerance and repairing skin barrier, and component saccharide isomeride is very similar to the composition of NMF in human skin and can be combined with free amino to form a layer of water-locking film, TEWL is reduced, and water production of the skin is improved; The moisturizing and soothing spray has the effects of quickly and deeply combining and moisturizing, promoting the generation of NMF, improving the barrier function of an epidermis barrier and relieving the symptoms such as dryness, scurf and pruritus.