The invention discloses a high-toughness hot-rolled 530 MPa-grade automobile cold stamping bridge shell steel plate and a manufacturing method thereof. The high-toughness hot-rolled 530 MPa-grade automobile cold stamping bridge shell steel plate comprises the following components of C, S, Mn, P, S, Al, Nb, Ti and the balance Fe and impurities; the content of the elements has to meet the followingrelationship at the same time, Nb+Ti is greater than or equal to 0.025% and is less than or equal to 0.045%, CEV is equal to C+Mn/6+(Cr+Mo+V)/5+(Ni+Cu)/15 and is less than or equal to 0.45%; the manufacturing method is characterized in that V is not added to the component design, Mn content is properly adjusted, a certain amount of Si, Nb, Ti and the like are added, molten iron pretreatment, molten steel smelting, continuous casting, cooling, heating, rolling, cooling, finishing, inspection and the like are carried out, so that the surface quality and strength of the steel meet the cold stamping and welding processing processes of the bridge shell steel; the yield strength ReL of the steel plate is greater than or equal to 375 MPa, the tensile strength Rm is greater than or equal to 530 MPa, the elongation percentage A after fracture is greater than or equal to 26%, the impact power KV2 at 0 DEG C is greater than or equal to 180 J, the grain size is 8-10 grades, the strip-shaped gradeis 1-3 grades, and cold stamping and forming of 10-16 mm specifications can be realized.