The invention discloses a novel neon gas protection explosive welding method. The novel neon gas protection explosive welding method comprises the following steps that S1, cleaning is conducted, specifically, the to-be-combined surfaces of a base plate and a compound plate are cleaned up; S2, assembling is conducted, specifically, the base plate and the compound plate which are cleaned up in the step S1 are assembled according to the principle that the base plate is located on the lower portion, the compound plate is located on the upper portion, and the to-be-welded surfaces are opposite, and a gap support is placed between the base plate and the compound plate; S3, explosive and detonator distribution is conducted, specifically, an explosive and a detonator are distributed on the upper surface of the compound plate; S4, a welding closed space is prepared, specifically, the base plate and the compound plate which are assembled in the step S3 are sealed through an aluminum-plastic hot melt film, and an air exhaust/inflation port and a gas component/pressure detection port are reserved in the diagonal positions; S5, neon gas is inflated, specifically, air in the closed space in the step S4 is exhausted, and the neon gas is inflated; and S6, explosive welding is conducted, specifically, the explosive is detonated through the detonator, and explosive welding is conducted. The situation that metal jet flow reacts with atmospheric components, and consequently brittle products are generated can be effectively avoided and weakened, the interface bonding quality is improved, and the welding strength is improved.