105 results about "Fundus (eye)" patented technology

The invention discloses an ocular surface illumination treatment device and method, and belongs to the technical field of ophthalmology medical equipment and treatment. The device comprises an infrared camera module, a computer terminal analysis control module, an optical power detection module, a mechanical adjustment module, a safety switch module and an illumination module. Wherein the infrared camera module comprises an infrared CCD (Charge Coupled Device) camera and a near-infrared light source which are arranged at a preset included angle and can collect eye images and transmit the eye images to the computer terminal, and the highest recording speed of the infrared camera module is not lower than 200 frames per second; and the computer terminal analyzes the image to obtain pupil positions, diameters and distances, and adjusts relative positions of a shielding device and a lens group in the light path of the illumination module, the axis of the light path and the distance between left and right lens cones, so that the central dark area of the annular light spot is matched and overlapped with the pupil. Eye images are collected and processed firstly, then light spots and the lens cone are adjusted, finally phototherapy and real-time monitoring are carried out, light can be prevented from entering the fundus, the treatment safety is improved, and the device is suitable for ocular surface diseases such as xerophthalmia.

The invention is suitable for the technical field of medical image processing, and provides a fundus fluorescence radiography report generation method based on a visual large model, and the method comprises the steps: pre-training a fundus fluorescence radiography visual large model, extracting the image features of a fundus fluorescence radiography sequence image through the fundus fluorescence radiography visual large model, and constructing a pseudo time sequence curve; based on the pseudo time sequence curve, key point detection is carried out, a plurality of phase periods are divided, and a phase weight is set for each phase period; calculating a comprehensive score for each frame of the pseudo time sequence curve based on the phase weight in combination with time novelty; based on the comprehensive score, combining a preset target key frame number to obtain a key frame sequence; based on the key frame sequence, a multi-view sequence image report generation model is combined, a Chinese diagnosis report is generated, the time sequence information and phase characteristics of the fundus fluorescence contrast sequence can be fully mined, the diagnosis report conforming to clinical specifications is generated, and the limitation of the prior art is effectively overcome.

The invention relates to the technical field of blood vessel image segmentation, and provides a fundus blood vessel image accurate segmentation method based on a U-Net model, aiming at solving the problem that the existing blood vessel segmentation method based on deep learning is difficult to effectively balance global context and local details. In order to solve the problem of inaccurate blood vessel structure segmentation caused by factors such as poor image quality and low contrast ratio, a method of combining a wavelet and a visual state space model and an adaptive dynamic fusion module is provided to improve the integrity of a slender blood vessel and the structural segmentation accuracy of a complex blood vessel network in a fundus blood vessel image. By integrating multiple efficient feature extraction mechanisms, accurate recognition of small blood vessels and the whole blood vessel structure is achieved, the accuracy and robustness of blood vessel segmentation in complex medical images are remarkably improved, and the method can be widely applied to analysis of eye blood vessels such as retinopathy and hypertensive fundus lesion and research of biomarkers related to the blood vessels.

The invention discloses a handheld rapid three-dimensional fundus blood supply imaging system and method.The system comprises an upper computer, a laser excitation module, a probe, a data collection module and a space positioning module, the laser excitation module, the probe, the data collection module and the space positioning module are connected with the upper computer, and the laser excitation module conducts wavelength conversion on input pump laser through the stimulated Raman scattering principle to generate excitation light; the exciting light is then transmitted to the probe for high-speed scanning, the probe receives real-time pose feedback of the space positioning module at the same time so as to eliminate the influence of operation jitter, the data acquisition module pre-processes a photoacoustic signal acquired by the probe and then transmits the photoacoustic signal to the upper computer, and a distribution diagram is generated through an image reconstruction algorithm and analyzed. According to the invention, four clinical troubles of poor molecular specificity, depth-resolution imbalance, low clinical adaptability and deficiency of quantitative standards in the existing imaging technology are fundamentally solved, and a universal tool is provided for early screening of eye ground ischemic diseases.

The utility model belongs to the technical field of ophthalmologic operations, and particularly relates to a forehead and chin supporting frame for the prone position of a fundus patient, which comprises a fixing plate, guide rods are symmetrically fixed on one side of the top of the fixing plate, a shielding pad is fixed on the top of one end of each guide rod, and a first supporting pad is fixed on one side of each shielding pad. The outer side of the other end of the guide rod is movably sleeved with an adjusting plate, moving openings are symmetrically formed in the side wall of the adjusting plate, the guide rod penetrates through the moving openings, a second supporting pad is fixed to the top of the adjusting plate, the first supporting pad and the second supporting pad are both made of elastic materials, and an elastic rod is fixedly connected to the middle of the side wall of the fixing plate. The outer side of the elastic rod is movably sleeved with an observation plate, and a mirror surface is arranged on the top face of the observation plate. The face of a patient is supported, the eyes of the patient are prevented from being pressed, meanwhile, medical staff can conveniently observe the situation of the eyes of the patient from multiple angles by adjusting the angle of the mirror face, and the practicability of the whole supporting tool is improved.

The invention discloses a modular integrated rapid ophthalmology screening vehicle and an examination method thereof, and relates to the technical field of ophthalmology examination. The inspection mechanism is mounted on the rear side of the bottom inner wall of the screening vehicle body; the two shading mechanisms are mounted between the top inner wall and the bottom inner wall of the screening vehicle body; through cooperative work of the vision detection module, the fundus imaging module, the intraocular pressure detection module, the slit lamp module and the AI auxiliary diagnosis module, and efficient interconnection between equipment in each module and the host server through USB-C and HDMI dual interfaces with unified specifications, the functional modules can be flexibly increased or decreased according to requirements of different screening scenes; the problems that a traditional whole machine integrated device is complex in structure and large in deployment difficulty are solved, multi-dimensional detection such as refraction detection, fundus imaging and intraocular pressure measurement can be completed through professional devices of all the modules, the screening efficiency and diagnosis accuracy are greatly improved, and the coverage range of ophthalmology screening service is effectively expanded.

An illumination apparatus for illuminating an examination object, in particular for illuminating a fundus section of a patient's eye, includes at least one light source which emits light onto a micromirror actuator, which is controllable by a control device for the purpose of preshaping the wavefront reflected by the micromirror actuator, and at least one light guide configured to guide the reflected light of the light source that has been preshaped by the micromirror actuator to an examination object. The light guide includes a first end for coupling light into the light guide and a second end for coupling light out of the light guide. In addition, an illumination method, and also an illumination system and a method for operating an illumination system are provided.

A scanning laser ophthalmoscope capable of obtaining visible light images and fluorescent images of the ocular fundus includes a visible light source; an infrared light source; a scanner configured to irradiate measurement lights onto a desired location on the ocular fundus of an eye to be examined in sequence; a beam splitter configured to separate the paths of the measurement lights and the reflected light; and a light detection unit for detecting the reflected light. The light detection unit includes a red light separation mirror; a red light detection unit; a green light separation mirror; a green light detection unit; a variable filter; and a blue light and fluorescence detection unit.

An ophthalmic apparatus of an embodiment example includes an image acquisition unit, image projection processor, blood vessel enhancement processor, denoising processor, and image compositing processor. The image acquisition unit acquires an optical coherence tomography angiography image of a fundus of a subject's eye. The image projection processor applies a projection process to the optical coherence tomography angiography image to generate a projection image. The blood vessel enhancement processor applies a blood vessel enhancing filter that is configured to enhance a blood vessel image to the projection image to generate a blood vessel enhanced image. The denoising processor applies a denoising process to the projection image to generate a denoised image. The image compositing processor applies an image compositing process to the projection image, the blood vessel enhanced image, and the denoised image to generate a composite image.

The application discloses a comprehensive ophthalmic imaging system based on a swept source OCT and a collection method thereof, which comprises a light source module with a swept laser, a main interferometer module, a reference arm, a sample arm suitable for an eye fundus mode, a control circuit module and a collection control analysis system, the light source module emits laser, the light beam enters the reference arm and the sample arm after passing through the main interferometer module, the return light signal enters the main interferometer module again to output an interference signal, the axis point of scanning is located at the pupil position of the anterior surface of the lens, and the collection control analysis system obtains the OCT image from the front end of the eye to the eye fundus according to the interference signal. The OCT image formed by the collection control analysis system is subjected to curvature correction, that is, a fan-shaped image from the vitreous body or the front end of the eye to the eye fundus is formed, the corrected retina is identified and circular or elliptical fitting is performed, and the real curvature of the eye fundus in the current scanning meridian plane is obtained.

The application relates to the technical field of optical imaging, in particular to an eye fundus blood flow imaging method and system based on cascade registration and a storage medium, which comprises the following steps: acquiring an eye fundus laser image sequence arranged according to a collection time sequence; based on the eye fundus laser image sequence, a plurality of mutually overlapped local time regions are divided according to the collection time sequence, local registration is performed on the eye fundus laser images in each local time region, and based on the eye fundus laser images after the local registration, a local structure image and a local blood flow image corresponding to the local time region are obtained; global unified registration is performed based on the local structure images, spatial transformation parameters corresponding to the local structure images are determined, and the spatial transformation parameters are synchronously applied to the corresponding local blood flow images to obtain a blood flow image sequence in a unified coordinate system; and fusion processing is performed on the blood flow image sequence in the unified coordinate system to obtain an eye fundus blood flow image. The application can improve the robustness, continuity and definition of eye fundus blood flow imaging.

The application discloses an end execution structure suitable for an eye fundus surgery scene and a use method, relates to the technical fields of intelligent medical equipment and surgical robots, and comprises a support trolley, a vertical moving mechanism, a rotary joint and at least one posture adjusting mechanism, wherein the vertical moving mechanism is installed on the support trolley; the rotary joint is installed on the vertical moving mechanism, the rotary joint is installed with a microscope, the rotary joint can drive the microscope to rotate, and an objective lens of the microscope extends downward to a target surgery position to form a line-of-sight channel; the posture adjusting mechanism is fixedly connected with the vertical moving mechanism, the posture adjusting mechanism is used for installing surgical instruments, so that the spatial posture of the surgical instruments can be adjusted through multi-degree-of-freedom motion, and the motion track of the posture adjusting mechanism is always constrained on the side and the lower side of the line-of-sight channel, so that the line-of-sight channel is kept unobstructed. The application improves the safety, accuracy and efficiency of the eye fundus surgery, fully utilizes existing medical resources, and reduces the clinical application threshold.

The invention relates to a gaze fixation system for an ophthalmic imaging instrument. The ultra-wide field ophthalmic imaging instrument includes: a rotatable mirror that scans with a light beam on a fundus of an eye via a focal point of an ellipsoidal mirror to acquire an ultra-wide field image of the fundus of the eye, a pupil of the eye being at another focal point of the ellipsoidal mirror; and a light source that projects fixation light for fixing the gaze of the eyes. The instrument also has a processor that controls the rotatable mirror to be stationary in a predetermined orientation and controls the light source to project fixation light onto the fundus via the rotatable mirror and the ellipsoidal mirror to fix a gaze direction of the eye. The processor then controls the ultra-wide field ophthalmic imaging instrument to acquire an ultra-wide field image of the fundus by controlling the rotatable mirror to scan with the light beam on the fundus via the ellipsoidal mirror.

(Ultra-Wide-Angle Ophthalmologic Imaging Apparatus Including Rotatable Mirror and Light Source for Projecting Fixation Light for Fixing Line of Sight of Eye, and Method Thereof) SOLUTION: An ultra-wide angle ophthalmic imaging device comprises a rotatable mirror and a light source for projecting fixation light for fixation of the line of sight of the eye. The rotatable mirror scans the light beam on the fundus of the eye through a focal point of the elliptical mirror, and the pupil of the eye is located at another focal point of the elliptical mirror to obtain an ultra-wide-angle image of the fundus of the eye. The apparatus also has a processor that controls the rotatable mirror to remain stationary at a predetermined orientation and controls the light source to project fixation light onto the fundus via the stationary mirror and the elliptical mirror to fix a gaze direction of the eye. The processor then controls the ultra-wide-angle ophthalmic imaging device to acquire an ultra-wide-angle image of the fundus by controlling the rotatable mirror to scan the light beam onto the fundus via the elliptical mirror.SELECTED DRAWING: Figure 1

The invention discloses an intelligent auxiliary diagnosis method for fundus lesions based on deep learning, and relates to the field of image recognition, and the method comprises the following steps: 1, obtaining the current eye state data of a target patient, and extracting the initial performance features of fundus blood vessels; 2, based on historical behavior data of the patient in a preset period, behavior feature extraction is carried out according to a preset reference index, the influence coefficient of each behavior feature on the initial performance feature is evaluated, and if the influence coefficient exceeds a preset threshold value, the behavior feature is marked as a reference feature; according to the invention, through quantitative evaluation and screening of the key behavior reference features influencing the blood vessel morphology, the initially segmented blood vessel trajectory is intelligently corrected and complemented by using the reference features, so that the problems of blood vessel fracture and adhesion caused by image quality or lesion interference are effectively overcome, and the system can understand the blood vessel change trend and improve the blood vessel quality. And personalized risk assessment and etiological association analysis are realized.

The utility model belongs to the field of manufacturing of auxiliary elements of microscopes, and particularly relates to a non-contact type fundus wide-angle observation mirror which comprises an inverted image and positive image switching device, a bottom plate, a space position mechanical adjusting mechanism and a wide-angle lens placer, and the inverted image and positive image switching device is arranged on the upper surface of the bottom plate. A wide-angle lens placer is arranged on the lower surface of the bottom plate through a spatial position mechanical adjusting mechanism, a light inlet area is reserved at a light inlet of the inverted image and positive image switching device on the bottom plate, the position under the light inlet area is within the travel range where the spatial position mechanical adjusting mechanism drives the wide-angle lens placer to move, and a mounting hole is formed in the bottom plate. According to the non-contact type fundus wide-angle observation mirror, the mode that the inverted image and positive image switching device is arranged to be matched with the space position mechanical adjusting mechanism and the wide-angle lens placer is adopted, the non-contact type fundus wide-angle observation mirror is designed, and the problem that holes do not need to be punched in eyeballs of a patient to fix the wide-angle observation mirror during an ophthalmologic operation is solved.

This product is a binocular indirect ophthalmoscope used for fundus examinations. A binocular indirect ophthalmoscope is a medical device that irradiates the patient's retina and its surrounding area for diagnostic purposes. Because the doctor can observe with both eyes, a three-dimensional field of view can be obtained.

The invention discloses a calculation method for standardized statistics of the area of a retinal fibrous vascular membrane, and the method comprises the following steps: employing a same non-contact wide-angle imaging system and a same amplification factor, and taking an optic disc as a center to shoot a standard eye model reference image containing a preset model vitreous head and an eye fundus image in a patient eye operation; by taking a vitreous body cutting head as a reference, aligning the two images through Canny edge detection, minimum circumcircle positioning and Hough transform, and zooming until the contour of the vitreous body cutting head coincides; the method comprises the following steps: carrying out graying, de-noising, Otsu segmentation, connectivity screening and edge fitting on the basis of a white highlight feature of an FVM (Fiber Virtual Machine), so as to obtain an FVM contour; and overlapping the grids to count the number of the covered grids, and finally calculating the actual area of the FVM according to a formula. The invention provides an FVM area quantification calculation scheme which is uniform in reference standard, accurate in quantification and wide in application range, and provides a uniform quantification standard for comparing the FVM resection efficiency of different surgical instruments.

A method of determining pathologic myopia by using the geometric structure of a posterior sclera of a fundus includes obtaining geometric location data about a fovea, an optic disc, and a deepest point of the eye (DPE) in the posterior sclera of the fundus; obtaining an elevation difference TEPSfovea−DPE between the fovea and the DPE, an elevation difference TEPSdisc−DPE between the optic disc and the DPE, and an elevation difference TEPSfovea−disc between the fovea and the optic disc by using location information about the fovea, the optic disc, and the DPE in the posterior sclera; and determining pathologic myopia by using at least two elevation differences selected from among the elevation difference TEPSfovea−DPE between the fovea and the DPE, the elevation difference TEPSdisc−DPE between the optic disc and the DPE, and the elevation difference TEPSfovea−disc between the fovea and the optic disc.

A model eye for examining the resolution of a fundus examining device includes one or more lenses corresponding to a cornea and / or a crystalline lens of an eye; and a chart unit located at an inner rear surface of the model eye corresponding to a fundus of an eye, and including two or more chart plates each having one or more resolution test chart for examining resolution of a fundus examining device. The chart plates are arranged at different positions so that the resolution test charts are located at the focal distances of the measurement lights of the fundus examining device which incident to a central region and peripheral region of the inner rear surface of the model eye through the lenses.

The invention discloses a special AI auxiliary device for fundus blood vessel anomaly detection, which comprises a base, a system terminal, a stand column, a lifting assembly, an anti-blink assembly, a sliding assembly, a cleaning assembly and a pressure assembly, and is characterized in that the system terminal is fixedly mounted on the base. Through an anti-blink assembly, after two curved groove blocks slide to the two ends of a hyperbolic rod respectively, a patient attaches the eyebrow bone to a gap in the hyperbolic rod, wears an elastic strap on the head, attaches an air support to the jaw through a lifting assembly, and then screws a second lead screw to enable a trapezoidal block to slide backwards, at the moment, the cambered surface of the support block descends along the inclined surface of the trapezoidal block, and the air support is fixed to the upper portion of the hyperbolic rod. When the head of a patient descends along with the air support, the double curved bars keep the eyelids at the eyebrow bones still, the downward movement of the head and the fixation of the double curved bars form relative displacement, so that the upper eyelids are stably pulled up, the eyelids are kept at the eye opening amplitude, the upper eyelids are prevented from naturally drooping or reflexively closing, and imaging missing or blurring caused by blinking and eyelid drooping is avoided; and the AI detection data is ensured to be complete and effective.

An ultra-wide angle ophthalmic imaging scanner is provided.SOLUTION: An ultra-wide-angle ophthalmic imaging scanner includes a rotatable mirror for scanning a light beam over a fundus via an elliptical mirror having the rotatable mirror at a first focus and a pupil of an eye at a second focus, a stereoscopic imaging device for acquiring a stereoscopic image of the pupil via the rotatable mirror and the elliptical mirror, and a processor for controlling the stereoscopic imaging device to acquire the stereoscopic image via the rotatable mirror and the elliptical mirror when the rotatable mirror is in a predetermined orientation, and for processing the stereoscopic image to generate an alignment signal to an imaging location of the pupil for ultra-wide-angle image acquisition of the fundus. The processor then controls the imaging scanner to scan the beam on the fundus via the elliptical mirror by rotating the rotatable mirror to obtain an ultrawide-angle image.SELECTED DRAWING: Figure 1

This technology provides a new way to observe the fundus of the eye being examined at a wide angle, with low cost and a simple configuration. [Solution] The fundus observation device includes an illumination optical system, a photodetector, an optical path splitting member, an optical scanner, a first concave mirror, a convex mirror, a second concave mirror, and an aspherical refractive optical element. The illumination optical system illuminates the fundus of the eye under examination with light. The photodetector receives the reflected light from the eye under examination. The optical path splitting member spatially divides the optical path of the reflected light from the optical path of the light from the illumination optical system. The optical scanner is positioned between the optical path splitting member and the illumination optical system and scans the fundus with light from the illumination optical system. At least one of the first concave mirror, the convex mirror, and the second concave mirror is configured asymmetrically in a first direction intersecting the optical path of the light from the illumination optical system, and the aspherical refractive optical element corrects the aberration component in the first direction.

The invention relates to a patient alignment system for an ophthalmic imaging instrument. An ultra-wide field ophthalmic imaging scanner includes a rotatable mirror that scans a fundus with a beam of light via an ellipsoidal mirror having the rotatable mirror at a first focal point thereof and a pupil of the eye at a second focal point thereof; the stereoscopic imaging device is used for acquiring stereoscopic images of pupils through the rotatable reflecting mirror and the ellipsoidal mirror; and a processor that controls the stereoscopic imaging device to acquire a stereoscopic image via the rotatable mirror and the ellipsoidal mirror while the rotatable mirror is held in a predetermined orientation, and processes the stereoscopic image to generate a signal for aligning the pupil with an imaging position for acquiring an ultra-wide field image of the fundus. The processor then controls the imaging scanner to acquire an ultra-wide field image by rotating the rotatable mirror to scan with the light beam on the fundus via the ellipsoidal mirror.

The invention provides a human eye wavefront aberration and refractive terrain comprehensive test system and method. The system comprises a head positioning module, an ocular surface positioning system, an optical test link, a motion control module, an image acquisition and processing module and a control module. During testing, human eyes and a system optical axis are aligned through head / ocular surface positioning, and initial refraction data compensation defocus is obtained; laser enters the eye through a link, a wavefront camera collects signals to calculate wavefront aberration, an array light source is matched with an area array detector to obtain large-view-field defocus data, and finally a refractive topographic map and wavefront aberration report is generated. According to the invention, the position of the fixation target and the position of the light source are conjugated, the fixation target and the light source form an inverted image relationship, the fixation target and the fundus are also conjugated, the fixation target and the fundus form an inverted image, and the light source at the light source end is asymmetrically distributed, so that stray light reflected to the fundus by the ocular surface of human eyes can be effectively avoided.

Imaging various regions of the eye is important for both clinical diagnostic and treatment purposes as well as for scientific research. Diagnosis of a number of clinical conditions relies on imaging of the various tissues of the eye. The subject technology describes a method and apparatus for imaging the eye using off-center illumination in a manner that avoids light striking the anterior surfaces of the eye at or near a center of the optical axis, thereby reducing reflections traveling back along an imaging light path, while also providing substantially uniform illumination of a region of interest of the fundus.

A model eye for evaluating a retinal imaging system includes a retinal cup and a resolution target. The retinal cup includes an interior surface having a bowl-like shape to represent a fundus of a human eye. The resolution target is disposed on the interior surface for assessing a spatial resolution of the retinal imaging system. The resolution target includes light and dark contrasting regions with straight edges separating the light and dark contrasting regions. At least two of the straight edges are orthogonal. An array of dark color microfeatures may be disposed in the light contrasting region and an array of light color microfeatures may be disposed in the dark contrasting region. The light and dark color microfeatures are variably sized for assessing the spatial resolution of the retinal imaging system.

The invention relates to the technical field of lighting equipment, in particular to a negative oxygen ion eye-protection lamp capable of inhibiting myopia and relieving asthenopia, which comprises an eye-protection lamp body, a lamp post and a negative oxygen ion generator, the eye-protection lamp body is used for emitting full-spectrum light; the negative oxygen ion generator is installed at the joint of the eye protection lamp body and the lamp pole, and the concentration of negative oxygen ions generated by the negative oxygen ion generator is 5000-5000 / cm < 3 >. When the eye protection lamp is used, the negative oxygen ion generator is arranged at the joint of the eye protection lamp body and the lamp pole, the negative oxygen ion generator can generate negative oxygen ions with the concentration of 5000-50000 / cm < 3 >, more dopamine is secreted by a living body through the negative oxygen ions, the fundus blood flow density and the fundus retina cell activity are improved, the choroid thickness is increased, and therefore the eye protection effect is improved. Therefore, the visual comfort is improved, and the effects of inhibiting myopia and relieving asthenopia are achieved.

A contact-type eye imaging apparatus including a light source, a light transmission structure optically coupled to the light source and positioned to emit light in a direction of a patient eye defining an illumination path, one or more optical lenses defining an imaging path, and a first polarizer positioned in the imaging path. Light emitted by the light transmission structure may be subsequently polarized, defining polarized illumination light. The first polarizer may be configured to at least partially cross-filter specularly reflected polarized illumination light from the patient eye.

The invention relates to oblique transscleral illumination of an eye fundus with at least one physical point light source around the eye allowing for dark field imaging combined with optical coherence tomography imaging.