196 results about "Fundus (eye)" patented technology

The invention discloses a large-field-of-view high-resolution fundus imaging system and method, and belongs to the field of adaptive optical imagines.The large-field-of-view high-resolution fundus imaging system is characterized in that light of a light source is divided into multiple beams by a beam splitter, and the multiple beams of light enter human eyes through a first spectroscope and an aberration correction module to be reflected by fundus; the multiple beams of reflected light carry respective small-view-field human eye aberrations, pass through the aberration correction module and are reflected by the first spectroscope to reach the confocal detection module; the confocal detection module collects small-view-field human eye aberration of the multiple beams of reflected light to generate multiple image signals and evaluates the aberration according to the quality of the multiple image signals so as to generate feedback signals to drive the aberration correction module to carry out aberration correction on the multiple beams of reflected light at the same time until the system reaches the diffraction limit. The large-view-field high-resolution fundus imaging system can synchronously correct aberration of different view fields, the aberration correction time is shortened, and the overall imaging speed is increased.

The invention discloses an ocular surface illumination treatment device and method, and belongs to the technical field of ophthalmology medical equipment and treatment. The device comprises an infrared camera module, a computer terminal analysis control module, an optical power detection module, a mechanical adjustment module, a safety switch module and an illumination module. Wherein the infrared camera module comprises an infrared CCD (Charge Coupled Device) camera and a near-infrared light source which are arranged at a preset included angle and can collect eye images and transmit the eye images to the computer terminal, and the highest recording speed of the infrared camera module is not lower than 200 frames per second; and the computer terminal analyzes the image to obtain pupil positions, diameters and distances, and adjusts relative positions of a shielding device and a lens group in the light path of the illumination module, the axis of the light path and the distance between left and right lens cones, so that the central dark area of the annular light spot is matched and overlapped with the pupil. Eye images are collected and processed firstly, then light spots and the lens cone are adjusted, finally phototherapy and real-time monitoring are carried out, light can be prevented from entering the fundus, the treatment safety is improved, and the device is suitable for ocular surface diseases such as xerophthalmia.

The invention is suitable for the technical field of medical image processing, and provides a fundus fluorescence radiography report generation method based on a visual large model, and the method comprises the steps: pre-training a fundus fluorescence radiography visual large model, extracting the image features of a fundus fluorescence radiography sequence image through the fundus fluorescence radiography visual large model, and constructing a pseudo time sequence curve; based on the pseudo time sequence curve, key point detection is carried out, a plurality of phase periods are divided, and a phase weight is set for each phase period; calculating a comprehensive score for each frame of the pseudo time sequence curve based on the phase weight in combination with time novelty; based on the comprehensive score, combining a preset target key frame number to obtain a key frame sequence; based on the key frame sequence, a multi-view sequence image report generation model is combined, a Chinese diagnosis report is generated, the time sequence information and phase characteristics of the fundus fluorescence contrast sequence can be fully mined, the diagnosis report conforming to clinical specifications is generated, and the limitation of the prior art is effectively overcome.

The invention relates to the technical field of blood vessel image segmentation, and provides a fundus blood vessel image accurate segmentation method based on a U-Net model, aiming at solving the problem that the existing blood vessel segmentation method based on deep learning is difficult to effectively balance global context and local details. In order to solve the problem of inaccurate blood vessel structure segmentation caused by factors such as poor image quality and low contrast ratio, a method of combining a wavelet and a visual state space model and an adaptive dynamic fusion module is provided to improve the integrity of a slender blood vessel and the structural segmentation accuracy of a complex blood vessel network in a fundus blood vessel image. By integrating multiple efficient feature extraction mechanisms, accurate recognition of small blood vessels and the whole blood vessel structure is achieved, the accuracy and robustness of blood vessel segmentation in complex medical images are remarkably improved, and the method can be widely applied to analysis of eye blood vessels such as retinopathy and hypertensive fundus lesion and research of biomarkers related to the blood vessels.

The utility model relates to a visual training mechanism based on a sighting mark, and the mechanism comprises a visual tube which is internally provided with a channel; the light source module is used for providing light spots with specified illumination intensity, size and shape, is arranged in the channel of the visual tube and can move along the length direction of the channel; the moving module is used for driving the light source module to move in the channel of the viewing tube; the light source module is arranged to be of a movable structure in the visual tube, the specific position of the light source module in the visual tube can be adjusted according to actual visual training requirements, and the visual training device has the advantages of being diversified in function and good in visual training effect. Meanwhile, the pattern on the sighting mark sheet of the light source module can enable the user to more directly and clearly sense the moving process of the light source module during forward and backward movement of the light source module during visual training, so that the ciliary muscle of the user can adjust the eyes of the user on the basis that the fundus receives illumination, and the visual training effect is improved.

The application discloses an eye fundus periphery aberration measuring device and relates to the technical field of optical instruments. The eye fundus periphery aberration measuring device comprises a mounting piece, a fog vision component and a measuring component. The mounting piece is in a bowl shape. The fog vision component is provided with a plurality of fog vision components, and the plurality of fog vision components are all mounted on the mounting piece and are used for projecting fog vision signals to the inside of the mounting piece in different directions. The measuring component is arranged outside the mounting piece. The mounting piece is provided with a measuring hole, and the measuring component is used for measuring the aberration of the eye fundus through the measuring hole. The technical scheme provided by the application enables the eye fundus periphery aberration measuring device to perform aberration measurement in a larger field of view angle range.

The invention relates to the field of fundus photograph enhancement and segmentation, and provides a fundus photograph enhancement segmentation method and device based on Diffusion, and the method comprises the steps: obtaining a fundus photograph, inputting the fundus photograph into a pre-trained Diffusion-based combined image enhancement segmentation model, and obtaining a fundus photograph enhancement image and a fundus photograph retinal blood vessel segmentation image; the model comprises a Diffusion-based image enhancement branch, an image segmentation branch and a symbiotic information interaction module, and the symbiotic information interaction module is used for realizing information flow between the image enhancement branch and the image segmentation branch, so that the image enhancement branch generates a fundus color photograph enhancement image based on a fundus color photograph and information from the image segmentation branch. Meanwhile, the image segmentation branch generates a fundus color photoretinal blood vessel segmentation image based on the fundus color photograph and information from the image enhancement branch. According to the invention, the understanding and analysis of the model on the image can be improved, and accurate blood vessel segmentation is provided while the image quality is improved.

The invention discloses a handheld rapid three-dimensional fundus blood supply imaging system and method.The system comprises an upper computer, a laser excitation module, a probe, a data collection module and a space positioning module, the laser excitation module, the probe, the data collection module and the space positioning module are connected with the upper computer, and the laser excitation module conducts wavelength conversion on input pump laser through the stimulated Raman scattering principle to generate excitation light; the exciting light is then transmitted to the probe for high-speed scanning, the probe receives real-time pose feedback of the space positioning module at the same time so as to eliminate the influence of operation jitter, the data acquisition module pre-processes a photoacoustic signal acquired by the probe and then transmits the photoacoustic signal to the upper computer, and a distribution diagram is generated through an image reconstruction algorithm and analyzed. According to the invention, four clinical troubles of poor molecular specificity, depth-resolution imbalance, low clinical adaptability and deficiency of quantitative standards in the existing imaging technology are fundamentally solved, and a universal tool is provided for early screening of eye ground ischemic diseases.

The utility model belongs to the technical field of ophthalmologic operations, and particularly relates to a forehead and chin supporting frame for the prone position of a fundus patient, which comprises a fixing plate, guide rods are symmetrically fixed on one side of the top of the fixing plate, a shielding pad is fixed on the top of one end of each guide rod, and a first supporting pad is fixed on one side of each shielding pad. The outer side of the other end of the guide rod is movably sleeved with an adjusting plate, moving openings are symmetrically formed in the side wall of the adjusting plate, the guide rod penetrates through the moving openings, a second supporting pad is fixed to the top of the adjusting plate, the first supporting pad and the second supporting pad are both made of elastic materials, and an elastic rod is fixedly connected to the middle of the side wall of the fixing plate. The outer side of the elastic rod is movably sleeved with an observation plate, and a mirror surface is arranged on the top face of the observation plate. The face of a patient is supported, the eyes of the patient are prevented from being pressed, meanwhile, medical staff can conveniently observe the situation of the eyes of the patient from multiple angles by adjusting the angle of the mirror face, and the practicability of the whole supporting tool is improved.

The invention discloses a modular integrated rapid ophthalmology screening vehicle and an examination method thereof, and relates to the technical field of ophthalmology examination. The inspection mechanism is mounted on the rear side of the bottom inner wall of the screening vehicle body; the two shading mechanisms are mounted between the top inner wall and the bottom inner wall of the screening vehicle body; through cooperative work of the vision detection module, the fundus imaging module, the intraocular pressure detection module, the slit lamp module and the AI auxiliary diagnosis module, and efficient interconnection between equipment in each module and the host server through USB-C and HDMI dual interfaces with unified specifications, the functional modules can be flexibly increased or decreased according to requirements of different screening scenes; the problems that a traditional whole machine integrated device is complex in structure and large in deployment difficulty are solved, multi-dimensional detection such as refraction detection, fundus imaging and intraocular pressure measurement can be completed through professional devices of all the modules, the screening efficiency and diagnosis accuracy are greatly improved, and the coverage range of ophthalmology screening service is effectively expanded.

An illumination apparatus for illuminating an examination object, in particular for illuminating a fundus section of a patient's eye, includes at least one light source which emits light onto a micromirror actuator, which is controllable by a control device for the purpose of preshaping the wavefront reflected by the micromirror actuator, and at least one light guide configured to guide the reflected light of the light source that has been preshaped by the micromirror actuator to an examination object. The light guide includes a first end for coupling light into the light guide and a second end for coupling light out of the light guide. In addition, an illumination method, and also an illumination system and a method for operating an illumination system are provided.

A scanning laser ophthalmoscope capable of obtaining visible light images and fluorescent images of the ocular fundus includes a visible light source; an infrared light source; a scanner configured to irradiate measurement lights onto a desired location on the ocular fundus of an eye to be examined in sequence; a beam splitter configured to separate the paths of the measurement lights and the reflected light; and a light detection unit for detecting the reflected light. The light detection unit includes a red light separation mirror; a red light detection unit; a green light separation mirror; a green light detection unit; a variable filter; and a blue light and fluorescence detection unit.

The application discloses an optical system and a method thereof for measuring an axial length, which comprises an OCT light source module, an OCT imaging module, an eye posterior segment OCT sample arm module and an anterior segment slit imaging assembly. The OCT light source module provides measuring light, which is incident on the fundus of an eye to be measured after passing through the eye posterior segment OCT sample arm module, and the OCT imaging module receives the measuring light to obtain an eye posterior segment OCT image. The anterior segment slit imaging assembly comprises an anterior segment slit light source module, an anterior segment slit imaging module and an anterior segment slit imaging adjustment light path module. The anterior segment slit light source module provides slit light, which is focused on the anterior segment of the eye to be measured after passing through the anterior segment slit imaging adjustment light path module, and the anterior segment slit imaging module receives the slit light to obtain an anterior segment slit image. The first optical path data and the second optical path data are obtained by using the eye posterior segment OCT image and the anterior segment slit image respectively, so that the axial length is calculated. The application avoids the influence of the movement of the eye to be measured, and improves the axial length measurement precision.

The embodiment of the invention relates to a cerebral apoplexy management method and device, equipment and a storage medium, and the method comprises the steps: segmenting a fundus blood vessel region from a fundus photo, and carrying out the recognition based on the fundus photo to obtain a first eye recognition result; calculating feature parameters of the fundus blood vessels based on the fundus blood vessel region; a retinal nerve layered image is obtained based on fundus OCT, a fundus lesion area is segmented from fundus OCTA, and a second eye recognition result is obtained based on fundus OCTA recognition; calculating feature parameters of retina nerve layering based on the retina nerve layering image, and calculating feature parameters of fundus lesion based on the fundus lesion area; and performing chronic disease information identification and / or cerebral vascular stenosis degree identification based on the feature parameters of the fundus blood vessels and the first eye identification result, and identifying the cerebral vascular stenosis degree based on the feature parameters of the retinal nerve layering, the feature parameters of the fundus lesions and the second eye identification result. Management of intelligent screening, risk prediction, progress monitoring and / or prognosis evaluation of the stroke population is carried out.

An ophthalmic apparatus of an embodiment example includes an image acquisition unit, image projection processor, blood vessel enhancement processor, denoising processor, and image compositing processor. The image acquisition unit acquires an optical coherence tomography angiography image of a fundus of a subject's eye. The image projection processor applies a projection process to the optical coherence tomography angiography image to generate a projection image. The blood vessel enhancement processor applies a blood vessel enhancing filter that is configured to enhance a blood vessel image to the projection image to generate a blood vessel enhanced image. The denoising processor applies a denoising process to the projection image to generate a denoised image. The image compositing processor applies an image compositing process to the projection image, the blood vessel enhanced image, and the denoised image to generate a composite image.

The utility model relates to fundus examination equipment which comprises a support, a first adjusting frame and a second adjusting frame which are respectively connected with the support, a medical magnifying lens connected with the first adjusting frame and a medical reflective mirror connected with the second adjusting frame. The medical reflector is used for reflecting light to eyes of a patient to facilitate observation. Medical instruments such as a medical magnifying lens and a medical reflective mirror required by fundus examination are fixed on the support through the first adjusting frame and the second adjusting frame, and the light equipment is also fixed on the support through the third adjusting frame, so that when a doctor performs fundus examination, the medical magnifying lens and the medical reflective mirror can be kept fixed; and a doctor can carry out various required operations more conveniently, and the safety of the examination process is also ensured.

The application discloses a comprehensive ophthalmic imaging system based on a swept source OCT and a collection method thereof, which comprises a light source module with a swept laser, a main interferometer module, a reference arm, a sample arm suitable for an eye fundus mode, a control circuit module and a collection control analysis system, the light source module emits laser, the light beam enters the reference arm and the sample arm after passing through the main interferometer module, the return light signal enters the main interferometer module again to output an interference signal, the axis point of scanning is located at the pupil position of the anterior surface of the lens, and the collection control analysis system obtains the OCT image from the front end of the eye to the eye fundus according to the interference signal. The OCT image formed by the collection control analysis system is subjected to curvature correction, that is, a fan-shaped image from the vitreous body or the front end of the eye to the eye fundus is formed, the corrected retina is identified and circular or elliptical fitting is performed, and the real curvature of the eye fundus in the current scanning meridian plane is obtained.

The application relates to the technical field of optical imaging, in particular to an eye fundus blood flow imaging method and system based on cascade registration and a storage medium, which comprises the following steps: acquiring an eye fundus laser image sequence arranged according to a collection time sequence; based on the eye fundus laser image sequence, a plurality of mutually overlapped local time regions are divided according to the collection time sequence, local registration is performed on the eye fundus laser images in each local time region, and based on the eye fundus laser images after the local registration, a local structure image and a local blood flow image corresponding to the local time region are obtained; global unified registration is performed based on the local structure images, spatial transformation parameters corresponding to the local structure images are determined, and the spatial transformation parameters are synchronously applied to the corresponding local blood flow images to obtain a blood flow image sequence in a unified coordinate system; and fusion processing is performed on the blood flow image sequence in the unified coordinate system to obtain an eye fundus blood flow image. The application can improve the robustness, continuity and definition of eye fundus blood flow imaging.

The application discloses an end execution structure suitable for an eye fundus surgery scene and a use method, relates to the technical fields of intelligent medical equipment and surgical robots, and comprises a support trolley, a vertical moving mechanism, a rotary joint and at least one posture adjusting mechanism, wherein the vertical moving mechanism is installed on the support trolley; the rotary joint is installed on the vertical moving mechanism, the rotary joint is installed with a microscope, the rotary joint can drive the microscope to rotate, and an objective lens of the microscope extends downward to a target surgery position to form a line-of-sight channel; the posture adjusting mechanism is fixedly connected with the vertical moving mechanism, the posture adjusting mechanism is used for installing surgical instruments, so that the spatial posture of the surgical instruments can be adjusted through multi-degree-of-freedom motion, and the motion track of the posture adjusting mechanism is always constrained on the side and the lower side of the line-of-sight channel, so that the line-of-sight channel is kept unobstructed. The application improves the safety, accuracy and efficiency of the eye fundus surgery, fully utilizes existing medical resources, and reduces the clinical application threshold.

The invention relates to a gaze fixation system for an ophthalmic imaging instrument. The ultra-wide field ophthalmic imaging instrument includes: a rotatable mirror that scans with a light beam on a fundus of an eye via a focal point of an ellipsoidal mirror to acquire an ultra-wide field image of the fundus of the eye, a pupil of the eye being at another focal point of the ellipsoidal mirror; and a light source that projects fixation light for fixing the gaze of the eyes. The instrument also has a processor that controls the rotatable mirror to be stationary in a predetermined orientation and controls the light source to project fixation light onto the fundus via the rotatable mirror and the ellipsoidal mirror to fix a gaze direction of the eye. The processor then controls the ultra-wide field ophthalmic imaging instrument to acquire an ultra-wide field image of the fundus by controlling the rotatable mirror to scan with the light beam on the fundus via the ellipsoidal mirror.

(Ultra-Wide-Angle Ophthalmologic Imaging Apparatus Including Rotatable Mirror and Light Source for Projecting Fixation Light for Fixing Line of Sight of Eye, and Method Thereof) SOLUTION: An ultra-wide angle ophthalmic imaging device comprises a rotatable mirror and a light source for projecting fixation light for fixation of the line of sight of the eye. The rotatable mirror scans the light beam on the fundus of the eye through a focal point of the elliptical mirror, and the pupil of the eye is located at another focal point of the elliptical mirror to obtain an ultra-wide-angle image of the fundus of the eye. The apparatus also has a processor that controls the rotatable mirror to remain stationary at a predetermined orientation and controls the light source to project fixation light onto the fundus via the stationary mirror and the elliptical mirror to fix a gaze direction of the eye. The processor then controls the ultra-wide-angle ophthalmic imaging device to acquire an ultra-wide-angle image of the fundus by controlling the rotatable mirror to scan the light beam onto the fundus via the elliptical mirror.SELECTED DRAWING: Figure 1

The invention discloses an intelligent auxiliary diagnosis method for fundus lesions based on deep learning, and relates to the field of image recognition, and the method comprises the following steps: 1, obtaining the current eye state data of a target patient, and extracting the initial performance features of fundus blood vessels; 2, based on historical behavior data of the patient in a preset period, behavior feature extraction is carried out according to a preset reference index, the influence coefficient of each behavior feature on the initial performance feature is evaluated, and if the influence coefficient exceeds a preset threshold value, the behavior feature is marked as a reference feature; according to the invention, through quantitative evaluation and screening of the key behavior reference features influencing the blood vessel morphology, the initially segmented blood vessel trajectory is intelligently corrected and complemented by using the reference features, so that the problems of blood vessel fracture and adhesion caused by image quality or lesion interference are effectively overcome, and the system can understand the blood vessel change trend and improve the blood vessel quality. And personalized risk assessment and etiological association analysis are realized.

The utility model belongs to the field of manufacturing of auxiliary elements of microscopes, and particularly relates to a non-contact type fundus wide-angle observation mirror which comprises an inverted image and positive image switching device, a bottom plate, a space position mechanical adjusting mechanism and a wide-angle lens placer, and the inverted image and positive image switching device is arranged on the upper surface of the bottom plate. A wide-angle lens placer is arranged on the lower surface of the bottom plate through a spatial position mechanical adjusting mechanism, a light inlet area is reserved at a light inlet of the inverted image and positive image switching device on the bottom plate, the position under the light inlet area is within the travel range where the spatial position mechanical adjusting mechanism drives the wide-angle lens placer to move, and a mounting hole is formed in the bottom plate. According to the non-contact type fundus wide-angle observation mirror, the mode that the inverted image and positive image switching device is arranged to be matched with the space position mechanical adjusting mechanism and the wide-angle lens placer is adopted, the non-contact type fundus wide-angle observation mirror is designed, and the problem that holes do not need to be punched in eyeballs of a patient to fix the wide-angle observation mirror during an ophthalmologic operation is solved.

This product is a binocular indirect ophthalmoscope used for fundus examinations. A binocular indirect ophthalmoscope is a medical device that irradiates the patient's retina and its surrounding area for diagnostic purposes. Because the doctor can observe with both eyes, a three-dimensional field of view can be obtained.

The invention discloses a calculation method for standardized statistics of the area of a retinal fibrous vascular membrane, and the method comprises the following steps: employing a same non-contact wide-angle imaging system and a same amplification factor, and taking an optic disc as a center to shoot a standard eye model reference image containing a preset model vitreous head and an eye fundus image in a patient eye operation; by taking a vitreous body cutting head as a reference, aligning the two images through Canny edge detection, minimum circumcircle positioning and Hough transform, and zooming until the contour of the vitreous body cutting head coincides; the method comprises the following steps: carrying out graying, de-noising, Otsu segmentation, connectivity screening and edge fitting on the basis of a white highlight feature of an FVM (Fiber Virtual Machine), so as to obtain an FVM contour; and overlapping the grids to count the number of the covered grids, and finally calculating the actual area of the FVM according to a formula. The invention provides an FVM area quantification calculation scheme which is uniform in reference standard, accurate in quantification and wide in application range, and provides a uniform quantification standard for comparing the FVM resection efficiency of different surgical instruments.

A method of determining pathologic myopia by using the geometric structure of a posterior sclera of a fundus includes obtaining geometric location data about a fovea, an optic disc, and a deepest point of the eye (DPE) in the posterior sclera of the fundus; obtaining an elevation difference TEPSfovea−DPE between the fovea and the DPE, an elevation difference TEPSdisc−DPE between the optic disc and the DPE, and an elevation difference TEPSfovea−disc between the fovea and the optic disc by using location information about the fovea, the optic disc, and the DPE in the posterior sclera; and determining pathologic myopia by using at least two elevation differences selected from among the elevation difference TEPSfovea−DPE between the fovea and the DPE, the elevation difference TEPSdisc−DPE between the optic disc and the DPE, and the elevation difference TEPSfovea−disc between the fovea and the optic disc.

The invention relates to a myopia prevention and control assembly and a myopia prevention and control light feeding instrument. The myopia prevention and control assembly comprises a condensing lens, an annular light source and an optical filter, the condensing lens comprises a first distance side end and a second distance side end, the area of a first side end of the first distance side end is larger than that of a second side end of the second distance side end, and the first distance side end and the second distance side end are designed to be provided with holes. The annular light source and the optical filter are connected and are both arranged at the first distance side end of the condensing lens; the first distance side end is the side end of the condensing lens with a short distance from the eyes of the target user, and the second distance side end is the side end of the condensing lens with a long distance from the eyes of the target user. According to the technical scheme, the pupil of the user is amplified, more red light sources enter the fundus of the target user, the uniformity of the red light entering the fundus of the target user and the sufficiency and safety of the light sources are improved, and the myopia prevention and control effect and use convenience of the myopia prevention and control assembly are further improved.

The present disclosure provides techniques and apparatus for capturing an image of a person's retina fundus, identifying the person, accessing various electronic records (including health records) or accounts or devices associated with the person, determining the person's predisposition to certain diseases, and / or diagnosing health issues of the person. Some embodiments provide imaging apparatus having one or more imaging devices for capturing one or more images of a person's eye(s). Imaging apparatus described herein may include electronics for analyzing and / or exchanging captured image and / or health data with other devices. In accordance with various embodiments, imaging apparatus described herein may be alternatively or additionally configured for biometric identification and / or health status determination techniques, as described herein.

An ophthalmic measurement device is provided and includes: a measurement optical system, projecting measurement light onto a fundus of an eye to be examined and receive a reflected light from the fundus by a light receiving element; a conversion member, arranged at a pupil conjugate position of the eye to be examined in the measurement optical system, converting the reflected light into multiple ring images; a limiting part, including a limiting member arranged at a conjugate position of the conversion member or in the vicinity of the conversion member, and changing a measurement region on the eye to be examined by limiting some of the ring images with the limiting member; a limiting controller, controlling the limiting part and causing the measurement region to change in at least two patterns; and a processor, processing the ring images and obtaining eye refractive power information.

An ophthalmic apparatus includes two or more curved mirrors, an illumination optical system, and a photographic optical system. The illumination optical system includes a slit with an aperture configured to be disposed at a fundus conjugate position, the fundus conjugate position being substantially conjugate optically to a fundus of an eye to be examined, and is configured to irradiate slit-shaped illumination light, that is generated by irradiating light from a light source onto the slit, onto the fundus through the two or more curved mirrors. The photographic optical system includes an image sensor configured to be disposed at the fundus conjugate position and to receive returning light from the eye to be examined through the two or more curved mirrors. The aperture is formed so that a width in a shorter direction differs depending on a position in a longitudinal direction.