The invention discloses an automated control system for a central air-conditioning system. The automated control system comprises multiple air openings and control modules, wherein each control module corresponds to the corresponding air opening. Each control module comprises an air direction module, an air volume module, an air exchange module, a refrigeration module, a heating module, a humidity module and a disinfection module. Each air opening comprises multiple vanes which are oriented in multiple different directions outwards. A temperature sensor is arranged at the periphery of each vane in a one-to-one-correspondence manner. According to the automated control system for the central air-conditioning system, firstly, the multiple vanes are arranged on each air opening, air can be blown in different directions, in addition, the air outlet angle is adjusted according to the temperature conditions at different positions, refrigeration or heating efficiency is changed, and the automated control system is adapted to different indoor environmental conditions; secondly, the carbon dioxide content, the air volume and the refrigerating capacity or heating capacity is pre-adjusted, and hysteresis is prevented; and finally, the humidity can be effectively adjusted, and the air is effectively disinfected and purified.