The invention relates to the technical field of flue gas treatment, in particular to a centrifugal production technology for gypsum separation. The technology at least comprises steps in sequence as follows: a slurry thickening step for adjusting solid mass fraction of diluted gypsum slurry to 20%-30%, a slurry homogenization step for stirring the slurry uniformly and a centrifugal dewatering step for realizing dewatering and washing of the slurry and scraping treatment of a filter cake. According to the production technology, impurities in a liquid can be removed effectively and concentrated to discharged liquor, on one hand, high-yield and high-quality gypsum products can be obtained, on the other hand, potential threat of impurity dispersion to the environment is eliminated, and therefore, the production technology is multi-purpose. With the adoption of the technology, fully-automatic production can be realized, online monitoring and control can be realized, data are stored automatically, a production statement is generated automatically, and besides, the technology has the advantages that the system integration degree is quite high, and the technological process is shorter, fewer material operation links are needed, totally-enclosed operation can be realized and the like, less influence is produced on the environment, and the technology is suitable for current industrial production.