The invention relates to a weave method of 2.5-dimensional overall braided multi-through pipe fabric. The weave method is characterized in that (1) the structure of the fabric adopts a 2.5-dimensional shallow-cross bended-connection structure; (2) the overall weaving of the fabric adopts core imitation-shaped weaving to ensure the internal molded surface dimension of the fabric; (3) the fabric is divided into two parts, namely a connecting body part and a through pipe part, wherein the connecting body is a part connected with the through pipes, while the through pipes are connected through the same connecting body; (4) the lower section of each through pipe is provided with warp yarns of the part in advance; (5) weft yarns between through pipes in the same plane are lined between the warp yarns layer by layer through adopting a weft insertion process; (6) when the horizontal section of the connecting body increases, warp yarns are increased through adopting a shift yarn adding method, and the method can effectively improve the hole phenomenon in yarn-adding points; and (7) when the horizontal section of the connecting body decreases, warp yarns are reduced through adopting a shift yarn reduction method. The 2.5-dimensional multi-through pipe fabric woven by the weave method has the advantages of better overall property, controllable shaping, high damage tolerance, excellent performances of impact resistance, delamination resistance, fatigue resistance, and the like.