The invention discloses an automatic loading and unloading processing center production line which comprises a loading machine, a processing center and an unloading machine, wherein the loading machine, the processing center and the unloading machine are sequentially transversely arranged side by side; the loading machine comprises a loading lathe bed, a cantilever beam and a sliding base, wherein a labeling head and a bar code printer are arranged on the sliding base; the processing center comprises a processing lathe bed, a portal frame, a sliding table and a machine head; and the unloading machine comprises an unloading rack, a conveying mechanism, an upper dust absorbing mechanism, a lower dust absorbing mechanism and a plurality of supporting pin mechanisms. According to the automatic loading and unloading processing center production line disclosed by the invention, the loading machine, the processing center and the unloading machine are arranged in a matched mode, so that the equipment can automatically and sequentially complete processes of loading, automatic bar code sticking, once milling type drilling and slotting, unloading and the like, can remarkably improve the working efficiency, can save wood processing manufacturing time, and can effectively increase the yield.