48results about How to "Improve stratification" patented technology

Methods are provided for classification of cancers by the expression of a set of genes referred to as the core serum response (CSR), or a subset thereof. The expression pattern of the CSR in normal tissues correlates with that seen in quiescent fibroblasts cultured in the absence of serum, while cancer tissues can be classified as having a quiescent or induced CSR signature. Patients with the induced CSR signature have a higher probability of metastasis. Classification according to CSR signature allows optimization of treatment, and determination of whether on whether to proceed with a specific therapy, and how to optimize dose, choice of treatment, and the like.

A mask pack impregnated with a liquid cosmetic preparation, being applied to a human skin surface, in particular a facial skin surface. The mask pack includes a nonwoven fabric layer and a nanofiber layer including a hydrophilic polymer, wherein said nanofiber layer is bonded to the nonwoven fabric layer.

The invention discloses a PMMA/ASA alloy material for a PVC profile coextrusion surface layer and preparation thereof. The PMMA/ASA alloy material is prepared from the following raw materials in percentage by ,mass: 0.5 to 3 percent of chain extender, 0 to 5 percent of inorganic nano particle, coupling agent accounting for 0 to 3 percent of the mass of the inorganic nano particle, and the balance of PMMA resin and ASA resin, wherein the mass ratio of the PMMA resin to the ASA resin is 1:0.25-4; the PMMA resin is polymethylmethacrylate resin; the ASA resin is acrylonitrile-styrene-acrylate grafted copolymer; and the chain extender contains groups which can react with the carboxyl. The PMMA/ASA alloy material has excellent performance such as high intensity, high toughness, high glossiness, friction and abrasion resistance, and the like.

The invention discloses a heat exchanger comprising a plurality of flat pipes (21), a collecting pipe (22) communicated with the flat pipe (21), an inlet pipe and an outlet pipe which are communicatedwith the collecting pipe (22). A plurality of clapboards (23) are arranged inside the collecting pipe (22) along the flowing direction of refrigerant, and a proper distance is left between the adjacent clapboards (23); and each of the clapboards (23) is provided with a passage (231) with a total equivalent diameter less than the geometric diameter of the collecting pipeline. The heat exchanger ensures that the refrigerant is mixed evenly inside the collecting pipe (22) and then evenly distributed into respective flat pipe (21) so as to improve the heat exchanging performance. Besides, the invention also discloses a heat exchanging device including the heat exchanger.

This invention is an improvement to the shape of liquid storage tanks, in particular to unpressurized molded polymer tanks used for thermal storage in solar systems. All aspects of this invention are well suited to solar storage tanks, and individual aspects are suited to other liquid tank applications.

This invention provides a formed horizontal extension at the bottom of the tank. From the top of this lower extension, a hollow vertical stub provides a reliable connection to a circulator pump. Thermal performance is enhanced by ensuring the lowest and coolest water is delivered to the array of rooftop solar collectors without entraining debris from the bottom of the tank.

At the top of the tank, a similar horizontal extension is used to distribute hot water returning from the solar collectors. Flow velocity is eliminated and a curving lower edge allows return water to find the matching thermocline to avoid de-stratifying.

The present invention relates to the field of biomarkers. More specifically, the present invention relates to biomarkers useful in diagnosing brain injury or neurodegeneration. In one embodiment, a method for diagnosing brain injury in a patient comprises the steps of (a) obtaining a sample from the patient; (b) determining the ratio of citrullinated to unmodified arginine residues at one or more arginine residues of one or more brain injury biomarker proteins; and (c) correlating the ratio to a patient having brain injury or to a patient not having brain injury, thereby providing the diagnosis.

The present invention relates to an apparatus, a system (100), a method (200), and a computer program for assessing the risk of an exacerbation and/or hospitalization. A patient's physical activity is measured (e.g., by an accelerometer (110)) during an active period of time (e.g., during awake hours) and during a rest period of time (e.g., during sleep hours) to gather first and second activity data. A risk of exacerbation and/or hospitalization is assessed (e.g., by a risk assessment unit (120)) based on an expression involving the respective activity data during active and rest periods fulfilling a predetermined relationship with respect to a predetermined activity level. For instance, low activity data during active periods and high activity data during rest periods indicates an increased risk of exacerbation and/or hospital readmission for the patient.

The invention discloses nutritional flavored composite sauce and a preparation method thereof, and belongs to the field of food processing. The method comprises the following steps: peeling and screening raw material seeds, carrying out ultrasonic soaking with a fructo-oligosaccharide solution with a certain concentration, carrying out microwave baking treatment, and carrying out sauce grinding toobtain a sauce material A; performing screening, superfine grinding and 80-100-mesh screening on the removed raw material skin to obtain raw material skin powder, then adding the raw material skin powder into vegetable oil preheated to 80 DEG C, and performing uniform stirring to obtain a sauce B; adding the sauce B into the sauce A, performing uniform stirring, performing homogenizing to obtaina sauce C, performing microwave sterilization, performing cooling, and performing filling so as to obtain the nutritional flavored composite sauce. The method is simple in process, low in energy consumption and low in cost. The obtained product is good in flavor, good in stability, free of layering, high in safety, high in nutritional value, rich in essential fatty acid and easy to digest and absorb.

The invention provides a composite acid fracturing construction pipe column and an application method, and belongs to the technical field of underground fracturing operation technologies. The composite acid fracturing construction pipe column comprises at least one spray gun with a sliding sleeve, a slotted pipe and a hollow guide head, the spray guns with the sliding sleeves are connected in sequence, the lower end of the last spray gun with the sliding sleeve is connected with the upper end of the slotted pipe, and the lower end of the slotted pipe is connected with the hollow guide head. Bymeans of the method, subsection reconstruction of different construction modes such as large-scale acid fracturing, fixed-point jet perforation, jet fracturing and the like is sequentially completedon a long open hole section by one pipe column, the layering and subsection reconstruction effects of clastic rock in an oil field are improved, the swept volume and complexity of the reconstructed fracture of a clastic rock reservoir are improved, and the fracturing yield increasing effect is improved. Mechanical packing is not needed, the pipe column structure is simple, the tool reliability andsafety are high, the pipe column meets different functional requirements, the construction continuity is good, the construction time is saved, the construction cost is reduced, and the oil field development effect is improved.

The invention relates to a method of pre-surgical risk stratification of a prostate cancer subject, comprising determining a gene expression profile for phosphodiesterase 4D variant 7 (PDE4D7) in a biological sample obtained from the subject, determining gene expression profile, and determining a pre-surgical prognostic risk score for the subject based on the expression based risk score and pre-surgical clinical variables of the subject. This may allow for an improved stratification of the subject in a pre-surgical setting that may result in better primary treatment decisions. For instance, the pre-surgical prognostic risk score may allow to make better recommendation on whether to select active surveillance vs. active intervention, e.g., radical prostatectomy, for certain sub-populations of prostate cancer patients.

Method for the production of metal products starting from ferrous material, by means of an electric arc furnace.

The invention provides an olanzapine orally disintegrating tablet. The olanzapine orally disintegrating tablet is composed of olanzapine, microcrystalline cellulose, mannitol, fructose, colloidal silicon dioxide, a disintegrating agent and a lubricant. The composition does not contain an aspartame flavoring agent. The olanzapine orally disintegrating tablet is low in weight (high in drug loading capacity of auxiliary materials), and has reduction of production procedures and production cost. The olanzapine orally disintegrating tablet has good mechanical strength in a low hardness range while achieving rapid disintegration and rapid action. The olanzapine orally disintegrating tablet meets requirements on hardness and friability in the processes of tablet preparation, production, transportation and use.

Use of tissue composition and anthropomorphic measures in a method for the detection and quantification of arterial calcification in an organ is described for disease risk prediction and stratification. A radiographic image of an organ is transformed quantitatively to a tissue composition map indicating a total amount of organ tissue; a calcification map is generated indicating position in the tissue composition map of calcified tissue; calcification free tissue composition map is generated from the tissue composition map using the position of calcified tissue in the calcification map; a vessel map of the position of vessels in the tissue composition map is generated; and the vessel map is combined with the calcification map to generate a map of vessel calcification indicating the position of calcified vessels in the tissue composition map. Scores are based on arterial calcification in a breast which indicates disease in the breast and other organs.