The invention discloses a nickel-chromium alloy wire. The nickel-chromium alloy wire is made from an alloy material, and the alloy material comprises the following ingredients: 1-2% of P, 0.9% of Te, 1.1% of Be, 0.7% of Sr, 0.3% of Nb, 19.5% of Cr, and the balance Ni and inevitable impurities; and the alloy material is prepared through the following steps: 1) melting Ni, P, Ni-Te alloy and Ni-Be alloy under a protective atmosphere; 2) adjusting a temperature to 975 DEG C, adding Ni-Sr alloy, Ni-Nb alloy and Ni-Cr alloy into a melt, uniformly stirring, and insulating heat and standing for 33 minutes; and 3) charging argon, and standing and cooling the melt to 675 DEG C, and carrying out die-casting to obtain the alloy material. The nickel-chromium alloy wire disclosed by the invention has a high electrical resistivity, high surface oxidation resistance, a high temperature class, and a high strength under a high temperature.