The invention relates to the field of molds, in particular to a clamp for machining a mold insert. The clamp comprises a base, two air cylinders and sliding rods driven by the air cylinders to slide correspondingly are arranged on the base, clamping blocks are arranged at the end parts, deviating from the air cylinders, of the sliding rods and are used for clamping the insert, the base is provided with a driving mechanism and a supporting block driven by the driving mechanism to ascend and descend, the supporting block is used for making contact with the bottom surface of the insert, the driving mechanism comprises a main shaft arranged on the base in a rotating mode, a crank is fixed to the main shaft, an eccentric shaft is fixed to the end part, deviating from the main shaft, of the crank and is sleeved with a rotating sleeve, a connecting rod is fixed to the rotating sleeve, and the end part, deviating from the rotating sleeve, of the connecting rod is hinged to the supporting block. According to the clamp, the insert can be turned over without loosening the clamp, the clamp does not need to be operated to clamp the insert after the insert is turned over, convenience is achieved, and therefore the efficiency is improved; the bottom surface of the insert can be stably supported, and the clamping blocks are not liable to hindering machining of the top surface of the insert; and when the main shaft rotates, rotation of the clamping blocks and the insert can be automatically completed, and the automation degree is high.