The invention discloses an integrated cross-region rescue support system, and each monitoring region is internally provided with an active detection protection system. The system comprises an active monitoring network, a passive monitoring network, an inclination detector and a camera. And the inclination detector, the Beidou positioning module and the camera in each monitoring area are in communication connection with the remote monitoring system. The mountainous area is divided into a plurality of monitoring areas, the base stations form a rescue network, the active detection and protectionsystem forms a disaster detection array, the disaster situation can be monitored in real time and reported in time through the base stations, related departments can find the disaster situation quickly, formulate a disaster relief scheme quickly and establish a disaster relief team, and achieves the efficient disaster emergency rescue command. The inclination detector can monitor rockfall, debrisflow, collapse and other disasters in real time, the Beidou positioning module can monitor the overall displacement of a mountain body, the camera can monitor the road condition of a rescue path in real time, and the best rescue path and strategy can be formulated conveniently during rescue.