The invention relates to a spatial soilless culture device. The spatial soilless culture device comprises a bracket, a plurality of culture beds, water wheels, a motor, a nutrient solution tank and a backflow tank, wherein two water wheels are arranged and are arranged at two sides of the bracket through a cross shaft, the cross shaft is linked with the motor through a belt, each of the water wheels is formed by a hollow pipe body, the periphery of each water wheel is provided with a series of water inlet pipes of which the front ends are bent to be hooked, the water inlet pipes are communicated with the water wheels, the two ends of the culture beds are movably connected to the pipe walls of the wheel bodies of the two water wheels through hollow connecting rods and are uniformly distributed on the water wheels, one end of each hollow connecting rod is communicated with the pipe body of the corresponding water wheel, the other end is communicated with the corresponding culture bed through a connecting rod, the nutrient solution tank is arranged below the water wheels, water holes are formed in the side edges of the culture beds, and the backflow tank is correspondingly arranged below the water holes. According to the culture device provided by the invention, plants can be shined uniformly, the water is automatically supplied and drained, and the nutrient solution is used cyclically, so that the automation and high efficiency of stereo-cultivation are realized, and the aims of energy saving and environmental protection are reached.