Disclosed is a highly processable steel sheet for a three-piece welded can, which is suitable for practical use. The highly processable steel sheet for a three-piece welded can contains, in mass%, more than 0.0015% but 0.0030% or less of C, 0.10% or less of Si, 0.20-0.80% (inclusive) of Mn, 0.001-0.020% (inclusive) of P, 0.001-0.020% (inclusive) of S, more than 0.040% but 0.100% or less of Al, 0.030% or less of N, 0.0002-0.0050% (inclusive) of B, with the balance made up of Fe and unavoidable impurities. The highly processable steel sheet for a three-piece welded can has a tensile strength in the transverse direction to the rolling direction of 400 MPa or more, and an elongation at break in the transverse direction to the rolling direction of 15% or more. The steel sheet is able to be obtained by hot rolling a steel, which has the above-described composition, at a finish rolling temperature of not less than the Ar3 transformation point but not more than 960 DEG C and a winding temperature of 560-750 DEG C (inclusive), then subjecting the resulting to a primary cold rolling at a reduction of 89-93% and an annealing at 600-790 DEG C, and then subjecting the resulting to a secondary cold rolling at a reduction of more than 6.0% but less than 10.0%.