The invention discloses an antibacterial composite tablecloth manufacturing method, belongs to the field of tablecloth manufacturing and aims to solve the problem that the prior art is bad in antibacterial effect, high in cost and complex in manufacturing process. The method includes: (1), improving diatomite to obtain surface-modified diatomite powder; (2), processing the surface-modified diatomite powder for standby use; (3), feeding existing plastic into a chopper for chopping; (4), putting plastic fragments obtained by chopping into multi-section hot melting equipment for hot melting; (5),adding thermostabilizer, chlorinated polyethylene aid and composite additive into thermally-molten plastic; (6), mixing the surface-modified diatomite powder with plastic particles, and feeding intorolling equipment after going through an extruder to obtain a corresponding face film; (7), press-fitting the obtained face film with cotton cloth on the undersurface, embossing, cooling, and windingto obtain corresponding composite tabletop. The method has the advantages of simple process, good antibacterial effect and simplicity in manufacturing.