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111results about How to "Reduce surface tack" patented technology

Preparation method of high-solid-content low-viscosity acrylate emulsion for sealing gum

InactiveCN103232566AMake up for the shortcomings of aggregationHigh solid contentOther chemical processesEster polymer adhesivesEmulsionChemistry
The invention relates to a preparation method of a high-solid-content low-viscosity acrylate emulsion for sealing gum. The preparation method is characterized by comprising the following steps of: in the presence of nitrogen, adding acrylate, a reactive emulsifier monomer, a latex protective agent and water to a vessel in a certain proportion, and uniformly stirring at room temperature to obtain a mixture liquid; and carrying out vacuumization and nitrogen introduction on a reactor repeatedly for three times, heating to 70-90 DEG C, adding an initiator aqueous solution which accounts for 0.1-0.8wt% of the monomer, dropwise adding 40 percent of the mixture liquid to the reactor, reacting for 15-30 minutes, adding a certain mass of anionic and non-ionic emulsifiers to the rest 60 percent of the mixture liquid to prepare a pre-emulsion, simultaneously dropwise adding the pre-emulsion and the initiator aqueous solution to the reactor, and keeping the constant temperature for 50 minutes after dropwise adding to prepare the acrylate emulsion. The preparation method has the advantages that the emulsion is high in solid content (70-82 percent), low in viscosity (300-600 mpa.s) and good in stability. The preparation method is used for preparing the acrylate-series sealing gum which is high in drying speed and small in shrinkage rate by adding the emulsion to filling and pigment paste.
Owner:LUDONG UNIVERSITY

Nintedanib inclusion compound and preparation and preparation method thereofof preparation

The invention provides a Nnintedanib inclusion compound and preparation and a preparation method thereofof the preparation. The inclusion compound comprises a main drug and an inclusion material, wherein the main drug is Nnintedanib or pharmaceutically acceptable salt in pharmacy, and the inclusion material is cyclodextrin or a derivative of cyclodrxtrin. The inclusion compound can sharply improvethe drug solubility of a simulated intestinal solution, the probability of the drug being separated out in the intestinal canal is lowered, and accordingly the bioavailability of the drug is improved. The inclusion compound and the preparation prepared from the inclusion compound and pharmaceutically acceptable ingredients in the pharmacy can outstandingly improve the dissolution degree and the dissolution rate of the drug in the simulated intestinal solution, the bioavailability of the drug is improved, meanwhile, the inclusion compound and the preparation have good stability, thus the flexibility and compliance of drug taking of patients are improved, and accordingly the treatment effect of the drug is improved. In addition, the invention provides a preparation method of the medicinal preparation of the Nnintedanib inclusion compound, no specific equipment is needed, the technology is simple, the production cost is low, and the preparation method is suitable for industrialized production.
Owner:SUNSHINE LAKE PHARM CO LTD

Multistage granulation equipment for ceramic pug

PendingCN112606170AOvercoming the problem of low granulation efficiencyRealize multi-stage continuous granulationCeramic shaping apparatusPore diameterSieve
The invention relates to the technical field of ceramic powder processing equipment, in particular to multistage granulation equipment for ceramic pug. The multistage granulation equipment for the ceramic pug comprises a granulation bin, wherein at least two friction granulation layers are arranged in the granulation bin; at least one friction granulation assembly is arranged on each friction granulation layer; and the pore diameter of each sieve pore of the friction granulation assembly at the lower layer is smaller than the pore diameter of each sieve pore of the friction granulation assembly at the upper layer corresponding to the friction granulation assembly at the lower layer. According to the multistage granulation equipment for the ceramic pug provided by the invention, the multiple friction granulation layers are arranged, and the sizes of powder particles prepared by the friction granulation assemblies of different friction granulation layers are reduced layer by layer, so that the problem of low granulation efficiency of existing single-layer granulation equipment is solved; in addition, dry air or hot air flow is introduced into the granulation bin through the air inlet, so that the mobility and / or the temperature of the air flow in the granulation bin are / is improved, and the powder particles are dried; and due to the fact that the specific surface area of the granulated particles is large, the drying speed is high, the drying cost is low, the surface viscosity of the dried powder particles is reduced, and the dried powder particles can fall off from the sieve pores easily.
Owner:FOSHAN LANZHIJING SCI & TECH CO LTD
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