The invention discloses a preparation method of Chinese patent medicine particles for treating psoriasis, and belongs to the field of pharmacy. The Chinese patent medicine particles for treating psoriasis are prepared from honeysuckle flower, weeping forsythia, divaricate saposhnikovia root, periostracum cicadae, dahurian angelica root, radix sophorae flavescentis, licorice, densefruit pittany root-bark, glabrous greenbrier rhizome, bark of Chinese corktree, raw rehmannia root, red paeony root, Chinese angelica, cane sugar, dextrin and water through processes. The Chinese patent medicine particles for treating psoriasis have small side effects, and after being taken, can fast activate a cell regulation and control system, release a cell protection enzyme, remove cells abnormally divided and thoroughly recover skin normal differentiation and metabolic functions. Practices prove that the Chinese patent medicine particles for treating psoriasis have good treatment effects.