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61 results about "Higher Order Structure" patented technology

CHROMATIN HIGHER-ORDER STRUCTURE. In the context of chromatin, “higher-order structure” may be defined as any assemblage of nucleosomes that assumes a reproducible conformation in 3D space. The most obvious chromatin higher-order structure is the mitotic/meiotic chromosome in which the DNA is compacted some 10,000- to 20,000-fold.

Circular Dichroism Fluorescent Microscope

According to a circular dichroism fluorescent microscope 100, in one embodiment of the present invention, it is possible to analyze, by using a small amount of a sample and directly in a living organism, a high-order structure of the sample such as a biomolecule, for example, protein and the like. The circular dichroism fluorescent microscope includes a confocal section. In the circular dichroism fluorescent microscope, a circularly polarizing/modulating section converts, into right and left circularly polarized lights, a light beam emitted from a light source. Thus obtained right and left circularly polarized light is focused on the sample so that the sample is irradiated with the right and left circularly polarized lights. Then, an optical lens focuses fluorescence emitted from the sample. Further, a wavelength selecting section transmits only fluorescence having a predetermined wavelength. Subsequently, the fluorescence having passed through the wavelength selecting section is detected. Based on fluorescent intensity signals of the fluorescence thus detected, a difference between an intensity of the fluorescence emitted from the sample at the time of irradiation with the use of the right circularly polarized light and an intensity of the fluorescence emitted from the sample at the time of irradiation with the use of the left circularly polarized light is calculated.
Owner:NARA INSTITUTE OF SCIENCE AND TECHNOLOGY

Higher order structure and binding of peptide nucleic acids

Peptide nucleic acids and analogues of peptide nucleic acids are used to form duplex, triplex, and other structures with nucleic acids and to modify nucleic acids. The peptide nucleic acids and analogues thereof also are used to modulate protein activity through, for example, transcription arrest, transcription initiation, and site specific cleavage of nucleic acids.
Owner:IONIS PHARMA INC +1

Carbon nanomaterial having higher order structure by means of multiple hydrogen bonds and method for preparing same

The present invention relates to a carbon nanomaterial having a higher order structure by means of multiple hydrogen bonds and to a method for preparing same. One of the key technical features of the present invention is a carbon nanomaterial having a higher order structure, in which a functional group capable of multiple hydrogen bonds reacts with a conductive carbon nanomaterial, into which said functional group is introduced by a surface modification to be functionalized, thus enabling multiple hydrogen bonds between carbon nanomaterials. In addition, another of the key technical features of the present invention is a method for preparing a carbon nanomaterial having a higher order structure by means of multiple hydrogen bonds, comprising: a first step of modifying the surface of a carbon nanomaterial to introduce a functional group for multiple hydrogen bonds into a conductive carbon nanomaterial; a second step of introducing a functional group capable of multiple hydrogen bonds by the reaction with the carbon nanomaterial functionalized in the first step; and a third step of preparing a paste using the carbon nanomaterial of the second step into which the multiple hydrogen bonds are introduced. As described above, a functional group capable of three or more multiple hydrogen bonds is introduced into a conductive carbon nanomaterial such as a carbon nanotube, graphene, carbon fiber or carbon black, thus inducing the formation of a supramolecular structure between materials and thus enabling the carbon nanomaterial of the present invention to be used for printed electronics. Furthermore, the carbon nanomaterial of the present invention can be utilized as an electrode for an energy storage element such as a secondary battery or a super capacitor when formed into a sheet-type conductive membrane, and can be applied for manufacturing conductive fibers.
Owner:KOREA ELECTROTECH RES INST

Method f amplifying dna chip signals

There is provided a signal amplification method for a DNA chip which can establish efficient signal amplification for a target gene captured on the DNA chip by the PALSAR method and can establish a simple detection by contriving design of a pair of HCPs to be used in the PALSAR method. Sensitivity for detection of the target gene on the DNA chip is improved by making use of a self-assembly reaction which forms a double-stranded self-assembly substance having a regular higher-order structure of oligonucleotides.
Owner:SANKO JUNYAKU CO LTD

Bidirectional multi-frequency rectangular lattice type tuned liquid damper

The invention provides a bidirectional multi-frequency rectangular lattice type tuned liquid damper and relates to a building structure shock controlling device. The bidirectional multi-frequency rectangular lattice type tuned liquid damper is formed by a rectangular-section container, a lattice plate, in-built solution and a fixed part. The damper is simple, practical, convenient to maintain, low in cost, suitable for use in a short term and in a long term, good in self-activation, small in required space, simple to install and convenient to use. The transverse and longitudinal earthquake reactions are controlled by adjusting transverse and longitudinal dimensions, the earthquake reactions under the effects of different formations can be controlled by adjusting the transverse dimension of a lattice, and the fact that a tuned liquid damper designed according to natural vibration frequency of a high-order structure is tall and narrow is avoid. The amount of the dampers is increased correspondingly according to increase of formation orders so as to improve sensitivity of controlling of high-order formation wind vibration and earthquake reactions. When meeting with an earthquake or strong wind, the bidirectional multi-frequency rectangular lattice type tuned liquid damper can reduce power reaction of a building structure and has good protecting effect on the building structure.
Owner:SHENYANG JIANZHU UNIVERSITY

Carbon nanomaterial having higher order structure by means of multiple hydrogen bonds and method for preparing same

The present invention relates to a carbon nanomaterial having a higher order structure by means of multiple hydrogen bonds and to a method for preparing same. One of the key technical features of the present invention is a carbon nanomaterial having a higher order structure, in which a functional group capable of multiple hydrogen bonds reacts with a conductive carbon nanomaterial, into which said functional group is introduced by a surface modification to be functionalized, thus enabling multiple hydrogen bonds between carbon nanomaterials. In addition, another of the key technical features of the present invention is a method for preparing a carbon nanomaterial having a higher order structure by means of multiple hydrogen bonds, comprising: a first step of modifying the surface of a carbon nanomaterial to introduce a functional group for multiple hydrogen bonds into a conductive carbon nanomaterial; a second step of introducing a functional group capable of multiple hydrogen bonds by the reaction with the carbon nanomaterial functionalized in the first step; and a third step of preparing a paste using the carbon nanomaterial of the second step into which the multiple hydrogen bonds are introduced. As described above, a functional group capable of three or more multiple hydrogen bonds is introduced into a conductive carbon nanomaterial such as a carbon nanotube, graphene, carbon fiber or carbon black, thus inducing the formation of a supramolecular structure between materials and thus enabling the carbon nanomaterial of the present invention to be used for printed electronics. Furthermore, the carbon nanomaterial of the present invention can be utilized as an electrode for an energy storage element such as a secondary battery or a super capacitor when formed into a sheet-type conductive membrane, and can be applied for manufacturing conductive fibers.
Owner:KOREA ELECTROTECH RES INST
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