The invention discloses an idiopathic atmospheric
hydrocephalus biomarker, a diagnostic kit and application, belongs to the technical field of biological
medicine, and particularly relates to the idiopathic atmospheric
hydrocephalus biomarker which is a
protein biomarker and comprises NBL1, TREM2, COL3A1, DPP7, PLA1A, SELENBP1, FGB, CCK, WFIKKN2, KNG1, HBA2, GFRA3 and CSF1. The invention relates to an application of an idiopathic atmospheric
hydrocephalus biomarker in preparation of an idiopathic atmospheric hydrocephalus diagnostic kit. Differential proteins are screened through a DIA technology,
protein expression is verified through a PRM technology, the idiopathic atmospheric hydrocephalus biomarker is obtained through screening and used for early screening,
risk assessment and prognosis judgment of iNPH, early, accurate and objective diagnosis of iNPH is achieved, the
clinical diagnosis period is shortened, and the diagnosis and treatment efficiency is improved.