44results about How to "Affect survival" patented technology

The present invention relates to the use of a non-digestible carbohydrate in the manufacture of a composition for treating or preventing pathogenic bacteria in the large intestine of a pet animal. It also provides a method for the prevention or treatment of a pathogenic bacteria in the large intestine of a pet animal, the method comprising administering to said pet animal a composition which comprises a non-digestible carbohydrate.

The invention provides a balanced drying system, comprising an air supply and exhaust main pipeline, and at least two groups of drying units; the drying units each comprises a unit air supply fan and a drying oven, the drying units each is provided with a unit air inlet and a unit air outlet, the drying oven is provided with a drying oven air inlet and a drying oven air outlet, and all of the groups of the drying units are disposed in pairs at intervals on the air supply and exhaust main pipeline via the unit air inlet and the unit air outlet, the unit air inlet is connected with the drying oven air inlet, and the unit air outlet is connected with the drying oven air outlet. The invention has the advantages of concise and stable system, simple adjustment, low exhaust air volume, low energy consumption and the like.

The present invention relates to methods of identifying antagonists of GPR22, a G protein-coupled receptor (GPCR) and related compositions and methods. Antagonists of GPR22 are useful as therapeutic agents for the treatment of ischemic heart disease, including myocardial infarction, post-myocardial infarction remodeling, and congestive heart failure.

The invention discloses application of histone methyltransferase EZH2 to preparation of a medicinal preparation for preventing or treating aortic diseases. The invention confirms that the EZH2 can effectively inhibit autophagy of vascular smooth muscle cells and promote the survival of smooth muscle cells; a novel target spot and strategy are provided for effective treatment of aortic dissection and other aortic diseases with reduction of the vascular smooth muscle cells as the basis of cytology, and a basic is provided for the development of a novel medicament for treating diseases of the type.

The present invention concerns compounds modulating apoptosis of neutrophil cells. In particular, the invention concerns compounds inhibiting an interaction between Proliferating Cell Nuclear Antigen (PCNA) and proteins binding to cytoplasmic PCNA in neutrophil cells, for use in the treatment of a disease involving a neutrophil-dependent inflammatory process. The invention also relates to a method for the identification of a compound for use in the treatment of a neutrophil-dependent inflammatory process. The invention further relates to peptides for use in the treatment of neutropenia.

The invention provides a lipid transport protein inhibitor, application thereof and an antibacterial drug. The target of the lipid transport protein inhibitor is located at one or more amino acid sites in a MlaFEDB protein complex; preferably, the target of the lipid transport protein inhibitor is located on at least one of MlaD protein, MlaF protein and MlaE protein. According to the invention, key amino acid sites participating in phospholipid transport in the MlaFEDB protein complex are studied, and it is found that multiple amino acid sites in MlaD protein, MlaE protein and MlaF protein play a key role in phospholipid transport, Once the functions of the amino acids are destroyed, the phospholipid transport efficiency can be remarkably influenced, and then bacterial survival is influenced. Therefore, development of antibacterial drugs by taking the amino acids as targets has very important significance.

The invention relates to the technical field of mouse killing, in particular to a mouse killing device. The mouse killing device comprises a scanning unit, an electromagnetic shooting unit and a controller, wherein the scanning unit is connected with the controller and is used for scanning a mouse target and sending scanning data to the controller; the controller is used for generating a shooting command according to the data sent by the scanning unit; the electromagnetic shooting unit is connected with the controller and is used for performing corresponding shooting action according to the shooting command. The living of the other animals is not affected by the mouse killing device provided by the embodiment of the invention, and the mouse killing efficiency can be improved.

The present invention relates to a new generation of chimeric antigen receptors (CAR) referred to as multi-chain CARs, which are made specific to the antigen CLL1. Such CARs aim to redirect immune cell specificity and reactivity toward malignant cells expressing the tumor antigen CLL1. The alpha, beta and gamma polypeptides composing these CARs are designed to assemble in juxtamembrane position, which forms flexible architecture closer to natural receptors, that confers optimal signal transduction. The invention encompasses the polynucleotides, vectors encoding said multi-chain CAR and the isolated cells expressing them at their surface, in particularly for their use in immunotherapy. The invention opens the way to efficient adoptive immunotherapy strategies for treating cancer, especially leukemia.

The invention provides a biological fermentation tank. The biological fermentation tank comprises a tank body; the bottom of the tank body is supported through a universal joint; the upper part of thetank body is connected with a sliding block through a chain; the sliding block is connected with a driving device; the driving device and the sliding block are arranged on a rotating rod; the rotating rod is connected with a rotation driving device; the upper part of the tank body is provided with a tank cover; an electric heating wire is embedded in the inner wall of the tank body; a vent pipe interface, an exhaust port and a temperature sensor interface are arranged in the tank cover; a one-way air outlet valve is arranged on the exhaust port; and a gate valve is arranged on the vent pipe interface. According to the invention, shearing action of a built-in stirrer on biological strains is avoided, a fermentation effect is good, the biological fermentation tank is suitable for fermentation processes of all aerobic organisms and anaerobic organisms, and control of the processes is accurate.

The invention discloses a system for regulating the loach water quality in a high-salt planting and breeding mode. The system comprises a high-salt planting and breeding pool, a sun shield, bases, natural plant planting pots, a sandstone plate, a microbial incubator, a thermometer body, a camera body, a regulation system control panel, a connecting column, an oxygen extractor body, a regulation system control shell, a water quality sensing module, an information receiving module, an information processing module, an information storage module, a GPS positioning module and an instruction outputmodule, the sandstone plate is arranged on the inner wall of the bottom of the high-salt planting and breeding pool, a plurality of mounting grooves are formed in the top of the sandstone plate, natural plant planting pots are arranged at two sides of the top of the sandstone plate, and the microbial incubator is arranged at the center of the top of the sandstone plate. The system for regulatingthe loach water quality in the high-salt planting and breeding mode abandons traditional manual monitoring, adopts machine monitoring to achieve time and labor saving and convenient and accurate monitoring, and allows a user to regulate the water quality according to the observation result in order to facilitate user operation.

The invention relates to a device for preventing feed mildewing in the frankliniella occidentalis feeding process and a use method. The device comprises a groove-type box body (1) with an open top, and a handle (5) is arranged on the outer side wall of the box body (1); fine sand (3) is laid in the box body (1), filter paper (4) is laid on the fine sand (3), and a green beam frame (2) is arrangedon the filter paper (4). The device has the advantages of being easy to operate, reasonable in design and capable of saving manual labor force and improving the breeding efficiency, in the process ofstudying the frankliniella occidentalis control problem in our country, a large number of indoor populations can be propagated rapidly for a laboratory to use, and the device can be applied and popularized in all research institutes and colleges and universities.

The invention belongs to the culture technical field, and especially relates to a sturgeon culture method comprising the following steps: fishpond treatment, inputting fish fingerling, water temperature control, and feeding; the method is simple, low in cost, can promote sturgeon growth, and improve sturgeon output, can improve sturgeon immunity, and can increase pathogen resistant ability, thus providing favorable conditions for sturgeon growth.

The invention provides a srp54k gene, and application of specific dsRNA of the srp54k gene to plagiodera versicolora prevention. On the basis of a sequence of the plagiodera versicolora srp54k gene, abacterial expression vector capable of expressing and targeting dsRNA of the gene is constructed, and the plagiodera versicolora is killed with poison through bacteria-expressed and bacteria-targetedthe dsRNA of the srp54k gene and spraying bacteria onto leaf surfaces. The dsRNA gene is high in silencing efficiency, has an obvious phenotypic change after being interfered, solves the problem thatthe plagiodera versicolora does not have effective dsRNA of the srp54k gene at present, and has a better application prospect in research and development of novel insecticides.

The invention discloses an NK cell culture medium form on-line monitoring device, and particularly relates to the field of cell culture. The NK cell culture medium form on-line monitoring device comprises a monitoring device box, a door plate is rotationally connected to one side of the monitoring device box, a culture mechanism and a moving mechanism are correspondingly arranged in the monitoring device box, a liquid conveying mechanism is arranged on the surface of the monitoring device box, and a discharging mechanism is arranged on the surface of the moving mechanism. Compared with the prior art, a liquid conveying pump is started, so that a nutrient solution enters a liquid storage pipe through a liquid conveying hose, an electric telescopic rod is started, so that a rubber piston disc downwards extrudes the nutrient solution in the liquid storage pipe, the nutrient solution drips into a culture dish, therefore, the automatic addition of the nutrient solution is conveniently completed, the convenience of adding the nutrient solution is effectively improved, and the situation that bacteria enter the culture dish to affect the survival of cells due to manual addition of the nutrient solution is effectively avoided.

The present invention belongs to the field of facial masks and particularly discloses a skin-whitening melatonin facial mask and a preparation method thereof. The skin-whitening melatonin facial maskcomprises essence liquid, a mask paper and a packaging bag; and the essence liquid is composed of deionized water, a moisturizer, a skin-whitening ingredient, an antioxidant, an anti-inflammation ingredient, xanthan gum and a pH regulator. The present invention also discloses the preparation method of the facial mask and also discloses the packaging bag used for packaging the facial mask. The preparation method can effectively solve a problem of Vc failure, also solves a problem that faces must be cleaned before use of the facial mask, thus eliminates melanin in time and protects the skin to the utmost.

The invention discloses a bionic hippocampus movement device and a driving method thereof. The bionic hippocampus movement device comprises a hippocampus shell, a control module, a tail mechanism, anoverturning device and a driving device. An overturning controller and a tail controller of a control module of the device are fixedly installed on a hippocampus shell and used for controlling a waterproof steering engine and a waterproof motor respectively, the waterproof motor controls a rope driving device to pull a rope, and therefore deflection movement of a tail mechanism is achieved. The steering engine controller controls the waterproof steering engine, and the waterproof steering engine drives the turnover blades of the turnover mechanism to move, so that the up-and-down movement andthe steering movement of the hippocampus are realized. The bionic hippocampus movement device imitates the shape and movement mode of hippocampus, can be used for conducting various underwater activities, and is sensitive in movement, simple in overall structure, low in cost and high in practicability.

A cysteine-rich undenatured whey-derived protein formulation did not interfere with the tumor-cytotoxic effects of chemotherapy and radiation therapy and did not have a negative effect on the clinical outcome, that is, negatively affect survival and increase mortality. Indeed, use of a high-cysteine undenatured whey derived protein in the treatment of cancer patients resulted in an increase in patient survival.

The invention relates to a heat pump treatment system of a sewage treatment circular aeration tank. In aeration, a sewage treatment system produces a large amount of heat so that a sewage temperature is continuously increased, microbe viability is influenced and an odor gas generation amount is increased. The heat pump treatment system comprises a cylindrical base, the top edge of the base is provided with an annular slide rail, a radial support is arranged above the slide rail, bottoms of the two ends of the support are provided with idler wheels, the idler wheels circlewise move along the slide rail, a radiator is arranged around the inner wall of the base, the radiator is a metal coil, the bottom surfaces of the idler wheels are provided with grooves and the slide rail is inserted in the grooves on the bottom surfaces of the idler wheels. The system can collect heat energy produced in aeration, prevents sewage temperature overspeed increasing-caused influence on microbe viability, reduces odor production, utilizes heat for indoor heating in a plant area and reduces an operation cost.

The invention relates to a plant grafting method adopting reverse grafting of a scion and a root stock. The plant grafting method is characterized by comprising the following steps of reserving a root stock coppice shoot good in growth on a plant which survives after grafting is completed by a conventional grafting method, then respectively cutting seams in the coppice shoot of the plant and the scion, enabling the seam of the coppice shoot to be aligned with and tightly attached to the seam of the scion so that the coppice shoot is grafted to the scion, and tying the coppice shoot and the scion which are grafted for cultivation. The grafting method is particularly suitable for high position grafting and grafting of tree species which are slow in growth vigor and poor in seam healing properties. According to the plant grafting method disclosed by the invention, the coppice shoot of the root stock can be utilized for promoting the growth of the scion, and the situations that the seam of the root stock dies and further the survival of the scion is influenced due to coppice shoot elimination can be avoided; and besides, the new plant of the scion can also grow firmly on the root stock, and wind and snow harm is reduced and avoided.

A cysteine-rich undenatured whey-derived protein formulation did not interfere with the tumor-cytotoxic effects of chemotherapy and radiation therapy and did not have a negative effect on the clinical outcome, that is, negatively affect survival and increase mortality. Indeed, use of a high-cysteine undenatured whey derived protein in the treatment of cancer patients resulted in an increase in patient survival.

The invention discloses an obtaining method of active honey with high honey enzyme. Antibacterial and disinfectant carbonized poplar is selected as a common living place of a swarm after strict environment and swarm screening, and then the activity cycle of bees is controlled through manual temperature control, so that the purpose of equal honey composition in each period can be achieved; meanwhile, degassing is performed through vacuum sterile stirring, oxygen in natural active honey is reduced greatly, the oxidase action is inhibited, and failure of the active honey with high water content due to conversion of too much sugar into hydrogen peroxide under the action of oxidase can be effectively prevented. The active honey has the characteristics of being pure natural, high in honey enzymecontent and activity and uniform in quality.

The invention belongs to the technical field of agricultural instruments, and particularly relates to a precise seedling feeding device for mechanically-transplanted large-bowl blanket-shaped seedlings. The precise seedling feeding device comprises a main body, a seedling storage box used for storing materials is arranged at the upper end of the main body, a seedling pushing block used for pushing the materials is arranged at the upper end of the seedling storage box, and a seedling feeding groove used for limiting is further formed in the upper end of the seedling storage box. A rectangular groove used for collecting sundries is formed in the seedling feeding groove, the seedling storage box is connected with a square block at the lower end through an internal material distributing device, a material conveying rack used for feeding is arranged at the square block, and one end of a fourth transmission gear is connected with a seedling transplanting device through a tooth groove by arranging a third transmission gear, and the other end of the fourth transmission gear is connected with the material conveying rack through the tooth groove. According to the precise seedling feeding device for the mechanically-transplanted large-bowl blanket-shaped seedlings, by means of the arrangement, transmission of the material conveying rack and a transmission rod is mutually connected, the operation speed of the transmission rod and the material conveying rack is synchronously adjusted through control of a motor at the position, then the seedling transplanting distance is adjusted, effective adjustment can be conducted according to different seedlings, and the using effect of the precise seedling feeding device for the mechanically-transplanted large-bowl blanket-shaped seedlings is improved.

The invention discloses a benthal deposit collecting system and method. The benthal deposit collecting system comprises a platform extending out of a ship, a vertical column arranged on the platform,a vertical cylinder with the open lower end, a plurality of ultrasonic ranging sensors arranged on the peripheral face of the vertical cylinder, and a plurality of drainage cylinders arranged on the vertical cylinder and arrayed in the circumferential direction of the peripheral face of the vertical cylinder, wherein the vertical cylinder is rotationally connected with the vertical column; the benthal deposit collecting system further comprises a supporting column arranged on the ship, an L-shaped corbel arranged on the supporting column, and a pallet arranged on the corbel; and a corbel motorused for driving the L-shaped corbel to rotate is arranged in the supporting column, and the corbel motor is electrically connected with a controller. The benthal deposit collecting system has the characteristics that automatic lifting can be achieved, a deposit layer can be taken out from benthos completely, operation is convenient, and the influence on the benthal environment is small.

The invention discloses an animal feeding device. The animal feeding device comprises a rearing cage, a placement rack and an independent air supply device, wherein the independent air supply device comprises an air supply device and a delivery pipeline, and a frame is arranged on the placement rack and comprises a moving rack and a fixed rack; a plurality of driving assemblies for enabling the moving rack to move are arranged on the placement rack; a sliding groove is formed in the placement rack; first sliders sliding in the sliding groove are arranged on the moving rack, and a rotating block is arranged on the placement rack; each driving assembly comprises an outer driving rod, an inner driving rod and a first spring, the inner driving rod and the outer driving rod are in sliding connection, a first annular groove is formed in the outer driving rod, the inner driving rod and the first spring are both located in the first annular groove, one end of the first spring is fixedly connected with the bottom of the first annular groove, and the other end is fixedly connected with the inner driving rod; when the rotating block moves in the circumferential direction, the rotating block drives the outer driving rods to move, so that the inner driving rods drive the first sliders to slide in the sliding groove; meanwhile, when the first sliders move, the direction of the moving rack keeps unchanged.