The invention discloses a radiation protection LED (light emitting diode) panel, which comprises a display unit, a control unit and a power supply unit, wherein the display unit comprises a box body and modules, the box body is provided with a plurality of modules, each module comprises a PCB (printed circuit board), an LED lamp and a driving chip, the control unit comprises a receiving card, a sending card and a controller, and the power supply unit comprises an AC/DC power supply arranged in the box body and a power supply cascade wire. The PCB comprises multiple layers which are sequentially arranged. The multiple layers of the PCB are two component layers, a power supply layer, at least one ground layer and at least one wiring layer, wherein the obverse side and the reverse side of the PCB are the component layers, the ground layer is below the obverse side and/or the reverse side of the PCB, the wiring layer is arranged between the power supply layer and the ground layer or is arranged between the ground layers. The PCB is provided with the independent and integral ground layer, thereby being capable of playing an effect of absorbing signal clutter, preventing electromagnetic radiation from spreading around, and avoiding influences imposed on operations of electronic equipment around.