The invention discloses a method for propagation and cultivation of Rauvolfia verticillata(Lour.)Baill.f.rubrocarpa H.T.Chang.mss., which includes the following steps: step 1, preparing a planting field of Rauvolfia verticillata(Lour.)Baill.f.rubrocarpa H.T.Chang.mss.: sowing a mixture of yeast, lactic acid bacteria, cassava powder and crushed eggshell on the planting field one year in advance, mixing the mixture with soil, planting green manure crops on the soil, and tedding the soil once after picking; step 2, breeding the plant of Rauvolfia verticillata(Lour.)Baill.f.rubrocarpa H.T.Chang.mss.: selecting seed propagation or cuttage propagation; step 3, carrying out artificial cultivation and planting: subjected Rauvolfia verticillata(Lour.)Baill.f.rubrocarpa H.T.Chang.mss. to field-planting on the planting field, and after field planting, conducting fertilization in three times, wherein the field planting density is (50-80) cm x (50-80) cm, the light intensity is 50-75% of natural light intensity, and the interval between every two times of fertilization is 2-3 months; step 4, carrying out management of weeding and irrigation in the planting field and control of pests and diseases; and step 5, carrying out harvesting: after field planting for 2-3 years, harvesting the Rauvolfia verticillata(Lour.)Baill.f.rubrocarpa H.T.Chang.mss. in September to November, and conducting natural air-drying. The method not only improves the yield of the Rauvolfia verticillata(Lour.)Baill.f.rubrocarpa H.T.Chang.mss., but also reduces the heavy metal content of medicinal materials of the Rauvolfia verticillata(Lour.)Baill.f.rubrocarpa H.T.Chang.mss., and has good production and medicinal prospects.