The present invention provides a lithium ion secondary battery having high capacity, high working voltage, and excellent load characteristics and excellent charge/discharge cycle characteristics when charges up at a high voltage. The lithium ion secondary battery has a positive electrode containing as an active material LipCoqMa(1-q)O2(A) and a compound (B) represented by general formula, LixNiyCozMb(1-y-z)O2, in a mass ratio of (B)/(A)=0.04 to 0.8, having a positive mix layer having a density of 3.7 g/cm<SP>3</SP>, wherein,0.5<=p<=1.2, 0<q<=1, 0.5<=x<=1.2, y+z<1, Y>0, z>0, Ma, Mb is at least one element selected from Al, Mn, Fe, Mg, Si, Ti, Zn, Mo, V, Sr, Sn, Sb, W, Ta, Nb, Ge, and Ba.