The invention relates to a silver arawana anti-inflammation feed, which is characterized by comprising the following components in parts by weight: 60 to 80 parts of duck meat powder, 10 to 20 parts of coconut leaf, 15 to 20 parts of egg yolk, 3 to 5 parts of bacillus subtilis, 5 to 8 parts of lysozyme, 5 to 10 parts of calcium dihydrogen phosphate, 20 to 40 parts of kelp powder, 15 to 30 parts of asarum herb powder, 10 to 20 parts of loach powder, and 10 to 20 parts of shrimp meal. The preparation method comprises the following steps: at first, grinding 10 to 20 parts of coconut leaf into powder with a size of 200 to 300 meshes, mixing coconut leaf powder with 15 to 30 parts of egg yolk, stirring, then adding 60 to 80 parts of duck meat powder, 3 to 5 parts of bacillus subtilis, 5 to 8 parts of lysozyme, and 5 to 10 parts of calcium dihydrogen phosphate, mixing, evenly stirring, transferring the mixture to a puffing machine to carry out puffing for 30 to 60 minutes at a puffing temperature of 60 to 75 DEG C under a puffing dryness degree of 50 to 60%, adding 20 to 40 parts of kelp powder, 15 to 30 parts of asarum herb powder, 10 to 20 parts of loach powder, and 10 to 20 parts of shrimp meal into the puffed mixture, evenly stirring, transferring the mixture to an extruding machine, extruding the mixture into strip-shaped feed with a diameter of 1.5 to 2.5 mm and a length of 3 to 5 cm, cooling, and packaging.