The invention discloses a non-slip surgical scalpel, which comprises a blade and a strip-shaped scalpel handle. A making method comprises the following steps: I, crushing the following materials in apulverizer: 50-60 parts of superfine tungsten carbide, 12-20 parts of strontium titanate, 8-10 parts of titanium carbide, 6-8 parts of chromium carbide, 4-8 parts of molybdenum disilicide, 7-9 parts of titanium nitride, 1-2 parts of vanadium carbide and 3-4 parts of graphite powder, so that mixed powder, which is less than 20mm in diameter, is formed; II, heating the mixed powder obtained from thestep I to 850 DEG C under a vacuum condition for 4h, then adding 4-6 parts of phenolic resin, fully stirring all materials uniformly so as to obtain a mixture, and cooling the mixture; III, forming and pressing the mixture via a press machine, so that a pressed blank is formed; and IV, sintering the pressed blank in a sintering furnace, so that a blade blank is formed. According to the multifunctional scalpel provided by the invention, the cutting edge is sharper, and hard tissues can be cut open quite easily; and the blade is quite shape, quite high in intensity and cannot get bent easily.