The invention discloses a high-power high-frequency switching power supply module and a device. The high-power high-frequency switching power supply module comprises an alternating-current input port,a rectifier bridge module, a power factor correction circuit, an LC filter circuit, at least one high-frequency DC/DC conversion module, an output filter capacitor, an output current sensor, a direct-current output port and a control module. The high-frequency DC/DC conversion module is composed of a high-frequency inverter bridge, a resonant inductor, a resonant capacitor, a high-frequency transformer, a high-frequency rectifying circuit, a high-frequency filtering capacitor and a current transformer. The input ends of N high-frequency DC/DC conversion modules are connected in parallel, andthe output ends of N high-frequency DC/DC conversion modules are connected in series or in parallel. The power supply module is simple in overall structure, can achieve high-power, low-ripple and low-load effect output, and can solve the technical problems that some equipment power supplies cannot meet the requirements of high power, high efficiency, high power factor, high power density, low output ripple, and being easy to replace and maintain at the same time.