The invention discloses neutral-point grounding control equipment of a medium-voltage power grid. The neutral-point grounding control equipment comprises a bus voltage transformer, a grounding transformer, a circuit zero-sequence current transformer and a controller, wherein the bus voltage transformer is connected with a bus and the controller, the grounding transformer is connected with the busand an arc extinguishing coil, a neutral point current transformer and a neutral point voltage transformer are arranged between the grounding transformer and the arc extinguishing coil and are connected with the controller, a branch is arranged between the neutral voltage transformer and the arc extinguishing coil and is connected with a resistor by a switch connected with the controller, the controller is connected with at least two branch lines by the circuit zero-sequence current transformer, and the branch lies are connected with the bus. The advantages of two grounding modes of neutral-point resonant grounding and resistance grounding are combined, the advantage that a line can be accurately selected by resistance grounding is maintained, residual current of a grounding point also canbe reduced, an arc light grounding overvoltage is limited, an appropriate working mode can be selected according to different conditions of a short-term grounding fault or a permanent grounding fault, the safety running of the line is guaranteed, and the power supply reliability is also improved.