The invention belongs to the field of active air-regulating agents used in storage and transportation, and particularly relates to an active air-regulating agent for an air-regulating temperature-control device. The active air-regulating agent for the air-regulating temperature-control device is characterized by comprising a carbon dioxide absorbent, a deoxidizing agent, an ethylene removal agent, a humidity control agent and a carbon dioxide releasing agent. By adopting the active air-regulating agent in the invention, influences from the proportion of nitrogen, oxygen, carbon dioxide, ethylene and the like in the gas on the storage of fruits and vegetables, and meat are reduced, and the active air-regulating agent has the effects of inhabiting the breath of cells, delaying the processes of after-ripening and aging, preventing water evaporation and restraining microbial activities; in addition, the oxide and carbon dioxide are controlled in an appropriate proportion, so that better fresh-keeping effect is achieved, and the storage and transportation of foods are facilitated.