The invention relates to a composition of novel nicotinamide insecticide nitenpyram. The preparation of the composition is a binary composition containing nitenpyram and the other insecticide. The other insecticide is buprofezin, pymetrozine, chlorpyrifos, thiamethoxam, fipronil, thiacloprid, dinotefuran, and the like. The preparation can be processed into new formulations of water dispersible granule, wettable powder, aqua, aqueous emulsion, soluble powder, colloidal suspension agent, and the like, wherein water is used as a solvent, an organic solvent is not used or used less so that the preparation has low toxicity and low residue and is environment-friendly. The nicotinamide insecticide is made of plant source farm chemical nicotinamide, and mainly acts on an acetylcholin esterase receptor of pests and the central nervous system of insects, thus the nicotinamide insecticide has high efficiency and selectivity and is safe to mammals. Compounded with other insecticides, the nicotinamide insecticide can improve the drug effect and enlarge the serviceable range. The novel nicotinamide insecticide is the optimal variety to replace highly-poisonous organophosphorus and organochlorine insecticides. The preparation of the novel nicotinamide insecticide is applied to controlling piercing mouth parts insects for rice, vegetables and other crops, and has the characteristics of low toxicity, low residue, less dosage, long lasting period, safety and no drug injuries to crops, and the like.