167 results about "Osteon structure" patented technology

An expandable implant is disclosed having an adjustable height for insertion between two adjacent bony structures or joint surfaces, for example between two adjacent spinal vertebrae. The implant includes at least one gear associated with at least one threaded shaft. Rotation of the gear engages the threaded shaft to expand the implant. The implant can be inserted in a collapsed configuration and expanded in situ. The invention also provides methods for using the implant to facilitate arthrodesis or fusion of adjacent joint surfaces or spinal vertebrae.

A spinal fusion implant of non-bone construction for introduction into any variety of spinal target sites. The implant may include generally arcuate anterior and posterior sides. The implant may also include a wedged shaped distal end which can provide self-distraction of vertebral endplates during insertion and positioning of the spinal fusion implant.

A bone screw assembly includes a first bone screw, second bone screw, and a coupler. The first bone screw defines a first axis and the second bone screw defines a second axis. The coupler is operably associated with the first bone screw and the second bone screw. The coupler is adapted to mount the first bone screw and the second bone screw to adjacent bone structures. The first axis of the first bone screw and the second axis of the second bone screw define an angle therebetween. The first bone screw and the second bone screw are securable to each other.

An interbody spinal implant having at least three distinct surfaces including (1) at least one integration surface having a roughened surface topography including macro features, micro features, and nano features, without sharp teeth that risk damage to bone structures; (2) at least one graft contact surface having a coarse surface topography including micro features and nano features; and (3) at least one soft tissue surface having a substantially smooth surface including nano features. Also disclosed are processes of fabricating the different surface topographies, which may include separate macro processing, micro processing, and nano processing steps.

A dynamic stabilization system including a dynamic rod with a first and second coupler assemblies, a pre-tensioned central cord and a flexible bumper, which are coupled to the bony structures of the spine by way of pedicle screws for use in spinal fixation surgery.

An interbody spinal implant, such as a solid-body or composite implant. The implant has at least one integration surface with a roughened surface topography including a repeating pattern, without sharp teeth that risk damage to bone structures, adapted to grip bone through friction generated when the implant is placed between two vertebral endplates and to inhibit migration of the implant. The repeating pattern is formed of at least three at least partially overlapping repeating patterns. The repeating patterns may radiate at a fixed distance from at least one point and may include recesses having a slope of thirty degrees or less relative to the integration surface. Also disclosed are processes of fabricating the integration surfaces.

An interbody spinal implant, such as a solid-body or composite implant. The implant has at least one integration surface with a roughened surface topography including a repeating pattern, without sharp teeth that risk damage to bone structures, adapted to grip bone through friction generated when the implant is placed between two vertebral endplates and to inhibit migration of the implant. The repeating pattern is formed of at least three at least partially overlapping repeating patterns. The repeating patterns may radiate at a fixed distance from at least one point and may include recesses having a slope of thirty degrees or less relative to the integration surface. Also disclosed are processes of fabricating the integration surfaces.

The present invention provides a technique for automatically generating bone shielding (82) in CTA angiography. This technique can preprocess the image data set (70) to perform various functions, such as removing (90) the image data associated with the table top, cutting (92) the volume into regionally consistent sub-volumes, calculating according to the gradient ( 110) Structure edges, and / or computing (112) seed points for subsequent region growing. The preprocessed data can then be automatically segmented for bone and vascular structures (78). This automatic vessel segmentation (118) can be accomplished using suppression region growing, where the suppression is dynamically updated according to the local statistics of the image data. The vasculature (78) may be subtracted (80) from the bone structure (76) to generate a bone shield (82). The bone mask (82) may in turn be subtracted (84) from the image dataset (70) to generate a boneless CTA volume (86) for volume-rendered reconstruction.

An apparatus and method for micro-exercise apply piezoelectric stress to cells of a bone mass by inducing voltages in the bone mass. Application of dynamic, electromagnetic fields passing through the conductive bone mass induce currents and voltages locally in and around cells or groups of cells. The cells respond to the combination of mechanical stress and strain by building themselves up as they would if they had been subjected to the stress and strain of conventional exercise. Thus, micro-exercise at a cellular level of the bone mass can be stimulated as if the stress and strain had been applied to the entire bone structure of which the smaller cellular portions are constituent parts. In combination with casts or splints, the sources of electromagnetic flux may be embedded in the frame or solid structure, the protective padding added for comfort, or both.

Methods and devices are disclosed for remodeling the tongue. One or more spaces or cavities are formed in the tongue using, for example, surgical or RF ablative techniques. The cavities can be closed or collapsed by inserting a tethered soft tissue anchor into the tongue and attaching the tethered portion of the soft tissue anchor to a bony structure such as the mandible or hyoid bone in order to exert a collapsing force on the one or more spaces or cavities. The insertion pathway of the tethered soft tissue anchor may pass adjacent to or even through one or more cavities. Also disclosed herein is a tongue remodeling system that includes means for creating a space in the tongue, and a tissue anchor configured to close the space. The tissue anchor may be tethered or expandable.

A method comprising: -providing acquisition data (34,38) of a patient, comprising acquisition data of a bone structure of the patient in a given position, providing a knowledge base (22,43,47), comprising data related to such bone structures, -determining a patient-specific position-specific finite-element model of the bone structure comprising: patient-specific three-dimensional geometry, patient-specific mechanical characteristics of the bone structure, and patient-specific position-specific mechanical load applied to the bone structure in the position.

Systems and methods for replacing, reconstructing and / or securing synthetic or biological connective tissue to interior and / or exterior bone surfaces. An anchoring apparatus and method of use are disclosed that secure a tendon or ligament within an interior opening of a bone structure. The apparatus comprises a securing device, a retention device, and an anchoring device. The securing device has an elongated body with an outer surface and an inner surface wherein the tendon or ligament fits between the interior of the open bone structure and the outer surface of the securing device. The retention device has an elongated body and a retention head, wherein the retention device securely fits within the interior surface of the securing device. The anchoring or holding device connects to the retention head of the retention device and extends outside the interior opening of the bone structure to engage the outer surface of the bone structure to hold the retention device and securing device in a fixed position inside the bone structure.

The present invention relates to a surgical kit, a saw guide and other related tools used in the osteotomy for temporary removal of a piece of a first bone structure to gain temporary access for treatment of defects of a second bone structure, as well as methods for designing and manufacturing said tools

In one form of the present invention, there is provided an apparatus for producing a virtual road map of a patient's vascular anatomy for use by a surgeon while conducting a procedure on the patient's vascular anatomy, the apparatus comprising: a virtual 3D model of the patient's anatomy, wherein the virtual 3D model comprises a virtual 3D structure representing bony structure of the patient and a virtual 3D structure representing vascular structure of the patient, with the virtual 3D structure representing bony structure of the patient being in proper registration with the virtual 3D structure representing vascular structure of the patient; a fluoroscope for providing real-time images of the bony structure of the patient and a surgical device being used in the procedure; registration apparatus for placing the virtual 3D model in proper registration with the patient space of the fluoroscope; bone mask subtraction apparatus for (i) generating a bone mask of the bony structure of the patient, and (ii) subtracting the same from the real-time images provided by the fluoroscope, whereby to create modified fluoroscope images omitting bony structure; and image generating apparatus for generating the virtual road map, wherein the virtual road map comprises a composite image combining (i) images of the virtual 3D structure representing vascular structure of the patient, and (ii) modified fluoroscope images omitting bony structure, wherein the images of the virtual 3D structure representing vascular structure of the patient are in proper registration with the modified fluoroscope images omitting bony structure.

A method for autonomous segmentation of three-dimensional nervous system structures from raw medical images, the method including: receiving a 3D scan volume with a set of medical scan images of a region of the anatomy; autonomously processing the set of medical scan images to perform segmentation of a bony structure of the anatomy to obtain bony structure segmentation data; autonomously processing a subsection of the 3D scan volume as a 3D region of interest by combining the raw medical scan images and the bony structure segmentation data, wherein the 3D ROI contains a subvolume of the bony structure with a portion of surrounding tissues, including the nervous system structure; autonomously processing the ROI to determine the 3D shape, location, and size of the nervous system structures by means of a pre-trained convolutional neural network (CNN).

A medical treatment system and method are provided for the treatment of tissue ailments, including weakened bone structures caused by fractures, osteoporosis, or other bone related ailments, and orthostatic hypotension, using a vibrating plate. The system and method use magnetic fields to provide vertical vibrational motion to a platform, thus allowing the system to have a lower profile.

The invention provides an exoskeleton auxiliary rehabilitation therapy system based on fluid transformation. The exoskeleton auxiliary rehabilitation therapy system comprises a tail end continuum mechanism, a driving system and guiding catheters, wherein the tail end continuum mechanism is composed of a base disc, interval discs, alloy wires and a tail end disc, one ends of the alloy wires are fixed with the tail end disc, the alloy wires can freely slide in the base disc and the interval discs, the driving system is composed of an instability resistant module, a fluid transformation mechanism and a movement driving mechanism, the alloy wires are connected with the fluid transformation mechanism through the instability resistant module, and the guiding catheters are used for guiding the other ends of the alloy wires to the driving system from the tail end continuum mechanism. The movement driving mechanism drives the fluid transformation mechanism to drive the alloy wires to perform push-and-pull movement so as to enable the tail end continuum mechanism to be turned and bent. The exoskeleton auxiliary rehabilitation therapy system based on fluid transformation can be self-adaptive to different muscle-bone structures of a patient, avoid damage to the joints of the patient and reduce driving errors caused by regulating hardware.

The invention discloses a humanization active forging bone and a preparation method thereof. The humanization active forging bone has main components of hydroxyapatite crystal, natural animal cancellous bones, particles of which the particle size is between 0.1 and 5 millimeters and having three-dimensional netlike porous structures, and a coating of which the pore-size distribution is between 50 and 600 microns and the surface is compounded with extracellular matrix synthesized and excreted by human cells. The forging bone not only has a similar structure with a human bone and is advantageous for cell ingrowth, formation of new bones, and bone structure reconstruction at a transplantation position, but also can be firmly combined with the coating of which the surface is coated with the extracellular matrix synthesized and excreted by the human cells and cell growth factors, promotes the attached growth of in vivo osteoblasts, and accelerates the formation of the new bones; and simultaneously, the forging bone has the advantages of molding randomly and not causing immunological rejection reactions, and can satisfy treatment needs of clinical bone defect and nonunion.

A composite interbody spinal implant including a body having a top surface, a bottom surface, opposing lateral sides, and opposing anterior and posterior portions; a first integration plate affixed to the top surface of the body; and an optional second integration plate affixed to the bottom surface of the body. At least a portion of the first integration plate, optional second integration plate, or both has a roughened surface topography including macro features, micro features, and nano features, without sharp teeth that risk damage to bone structures, adapted to grip bone through friction, inhibit migration of the implant, and promote bone growth. Also disclosed are processes of fabricating a roughened surface topography, which may include separate and sequential macro processing, micro processing, and nano processing steps.

The invention relates to a method for producing a tooth plant positioning guiding template, comprising the following steps: (1) scanning the jaw bone of sufferers by multiple-layer helix CT to obtain the three dimensional anatomy structure information of the jaw bone; (2) establishing a three dimensional jaw bone model in CAD software; (3) measuring the bone structure of the plant area lack of tooth according to the three dimensional jaw bone model; (4) confirming the plant point, direction and depth of the dental implant according to the measuring result; (5) producing the positioning guiding template entity model based on dental face- bone face combination support type by applying photo-curing rapid forming technology; (6) having surface treatment to the positioning guiding template entity prototype. The advantage of the invention is that: a surgery positioning guiding template adopts a retention method of dental face-bone face combination support with accurate retention, high precision and convenient process.

The invention relates to a 3D-printed multi-structure bone composite scaffold. The 3D-printed multi-structure bone composite scaffold comprises a multi-layer structure, wherein different layers are made of composite materials in different proportions through 3D printing, and the 3D-printed multi-structure bone composite scaffold has different 3D printing fiber spacings and porosity factors. The specific structure comprises a bionic bone structure, the outer layer is low in porosity and small in aperture to simulate a compact bone structure, the inner layer is high in porosity and large in aperture to simulate a cancellous bone structure, and the scaffold similar to a real bone structure is integrally formed; in an osseointegration structure, the outer layer is high in porosity and large inaperture so as to promote integration with surrounding bones, the inner layer is low in porosity and small in aperture so as to support the overall structure while promoting osseointegration, and thewhole structure is suitable for repairing bone defects. The material of the scaffold is preferably a composite material of tricalcium phosphate (TCP) and polycaprolactone (PCL), and the scaffold hasgood biocompatibility and printability. The bone repair effect is promoted by adding metal ions and performing surface modification treatment.

An interbody spinal implant including a body having a top surface, a bottom surface, opposing lateral sides, and opposing anterior and posterior portions. At least a portion of the top surface, the bottom surface, or both surfaces has a roughened surface topography including both micro features and nano features, without sharp teeth that risk damage to bone structures, adapted to grip bone through friction generated when the implant is placed between two vertebrae and to inhibit migration of the implant. The roughened surface topography typically further includes macro features and the macro features, micro features, and nano features overlap. Also disclosed are methods of using such implants and processes of fabricating a roughened surface topography on a surface of an implant. The process includes separate and sequential macro processing, micro processing, and nano processing steps.

A fenestrated bone screw and method of use is disclosed in which a bone cement injection tube may be readily and sealably connected to the head of the bone screw by means of a bayonet connector so that bone cement from a cement pump may be forced into a cannula of the bone screw and into the bone structure proximate the fenestrations of the bone screw. Upon completion of the injection of the bone cement, the cement tube may be readily disconnected from the bone screw in such manner that leakage of bone cement is minimized. A surgical method of injecting bone cement into bone structure using such a cannulated, fenestrated bone screw is also disclosed.

The invention discloses a micro / nano-fiber bone repairing scaffold. The scaffold is obtained by adding composite particles to degradable polymers of engineering scaffolds for bone repair and producing micro / nano-fibers. The composite particles are provided with a core-shell structure, the core is a polymer particle prepared by high polymer materials or a bionic active microsphere similar to a bone structure in a micro-scale, the shell is medical biodegradable inorganic salt, and the bionic active microsphere similar to the bone structure in the micro-scale is composed of high polymer materials and inorganic salt. The micro / nano-fiber bone repairing scaffold has high activity and is capable of better absorbing and inducing cells to grow; the medical biodegradable water insoluble inorganic salt shell can protect collagen, growth factors and / or medicine in the composite particles, and repair of bone tissue is facilitated due to the bionic active microsphere similar to the bone structure in the micro-scale with an inorganic-organic intercalated structure and a human body simulation structure.

The invention relates to the technical field of medical apparatus and instruments, and particularly discloses an endoscope snake bone structure and an endoscope. The endoscope snake bone structure comprises two or more snake bone units which are connected end to end, the adjacent snake bone units are connected through a pivot joint mechanism, the inner surface of a rotation groove of a pivot female joint is an inner conical surface of which the radius gradually increases from the outer walls to the inner walls of the snake bone units, the outer surface of a rotation portion of a pivot male joint is an outer conical surface of which the radius gradually increases from the outer walls to the inner walls of the snake bone unit, and the maximum radius of the outer conical surface is larger than the minimum radius of the inner conical surface. According to the endoscope snake bone structure, the adjacent snake bone units can relatively rotate around a pivot joint structure, accordingly, the adjacent snake bone units cannot be separated in the radial direction, through a processing mode of material removal, hollowed-out processing integrated shaping is conducted, assembly among the snake bone units is not needed, the machining efficiency is improved, and the stability and reliability of the structure are also improved.

The invention provides a method for preparing an absorbable and antibacterial guided tissue regeneration membrane for a bone-like structure, and belongs to the field of biological medical materials. The method comprises the following steps: firstly, preparing a cell free bovine pericardial collagen fiber membrane by adopting a repeated freeze-thaw method and a surface active agent TritonX-100, or preparing a demineralized cell free collagen fiber membrane of a cattle lamellar bone by using a method of EDTA decalcification by using the surfactant TritonX-100; treating by using sodium trimetaphosphate to obtain a phosphorylated collagen fiber membrane; with the assistance of a direct-current electric field, mineralizing in agar hydrogel containing calcium and phosphate, thereby obtaining a mineralized collagen membrane with a bone-like structure with certain hardness; and finally soaking the mineralized collagen membrane into a minocyline solution, and preparing an antibacterial bone-like structured composite membrane structure by virtue of the characteristics of combined minocyline and hydroxyapatite. The guided tissue regeneration membrane provided by the invention has a bone-like structure, is capable of maintaining a bone defect space, is good in operation forming property and antibacterial property, and can be applied to clinical practice for bone defect remediation and reconstruction in periodontal departments, dental implant mediation and occlusalf surfaces.

Bone-adaptive surface structures are provided for lateral jaw implants. Micromechanical and / or macromechanical surface structures having various body forms are incorporated into selected segments of the surface of a base and of a bar that connects a shaft with the base to accelerate the healing process after the implant is inserted into the jaw bone and to make a critical improvement in holding the implant firmly in place without rotation. A process of manufacturing the surface structures includes forming a macromechanical surface on the implant to increase its surface area; and superimposing micromechanical canals on the macromechanical surface, the canals having a size smaller than the minimum size of the osteons in the bone into which the implant is to be inserted.

A computer-implemented system: at least one processor communicably coupled to at least one nontransitory processor-readable storage medium storing processor-executable instructions or data receives segmentation learning data comprising a plurality of batches of labeled anatomical image sets, each image set comprising image data representative of a series of slices of a three-dimensional bony structure, and each image set including at least one label which identifies the region of a particular part of the bony structure depicted in each image of the image set, wherein the label indicates one of a plurality of classes indicating parts of the bone anatomy; trains a segmentation CNN, that is a fully convolutional neural network model with layer skip connections, to segment semantically at least one part of the bony structure utilizing the received segmentation learning data; and stores the trained segmentation CNN in at least one nontransitory processor-readable storage medium of the machine learning system.

The present invention relates to scanning confocal microscopy used to systematically quantify characteristic collagen fibril orientations by position within the lamellar thickness of secondary osteons along the osteon radial direction. Fully calcified lamellar specimens appear either extinct or bright in cross-section under circularly polarized light, and can be isolated from embedded osteon, flattened, and examined along the radial thickness direction of the original embedded osteon. Collagen orientation is measured from confocal image stacks. Extinct and bright lamellae display distinct patterns of collagen orientation distribution. Relative counts of collagen fibrils that are longitudinal to the osteon axis in extinct lamellae, transverse to the osteon axis in bright lamellae, and oblique to the osteon axis in both lamellar types, show parabolic distribution through the osteon radial direction.