62 results about "Pain killer drug" patented technology

A composition containing capsicium extract together with other ingredients to neutralize the discomfort resulting from the application of capsicium extract to the skin enabling treatment of many types of discomforts, including arthritis pain, neuropathy, post surgical scarring, hemorrhoid pain and itching, and pruritis without the discomfort normally associated with the topical application of capsicium extract.

A composition containing capsicium extract together with other ingredients to neutralize the discomfort resulting from the application of capsicium extract to the skin enabling treatment of many types of discomforts, including arthritis pain, neuropathy, post surgical scarring, hemorrhoid pain and itching, and pruritis without the discomfort normally associated with the topical application of capsicium extract.

The present invention relates to a compound analgesic composition for combination of symptomatic treatment and causal treatment, comprising analgesics with a weight ratio of 5∽200, and 0.1∽5000 weight ratio of other analgesics acting on the circulatory system, Drugs and excipients for one or more systems in the motor system and nervous system. The invention has the characteristics of good effect, emphasizing both symptomatic and causal treatment, and treating both symptoms and root causes, and is also a discussion on the combination of traditional and modern medicine.

The present invention is flurbiprofen ester injection as antiphlogistic and analgetic medicine and its preparation process. Main medicine and supplementary material including solvent, emulsifier, isotonic agent, buffering agent and pH regulator are mixed to compound the injection. Compared with available oral flurbiprofen preparation, the flurbiprofen ester injection has even high curative effect, even fast action, long lasting effect and less stomach mucous membrane damage and other negative effect. The present invention is used in treating chronic rheumarthritis, etc and is especially suitable for relieve post-operational pain and pain caused by cancer, and it has high effect and no addiction.

An antalgic Chinese medicine for treating headache, hemicrania, toothache, rheumatalgia, menalgia, etc. is prepared from 4 Chinese-medicinal materials: gastrodia tuber, dahurian angelica root, Chuan-xiong rhizome and shrub chastetree fruit.

Pharmaceutical compositions comprising a proton pump inhibitor, one or more buffering agent, a sleep aid and acetaminophen, ibuprofen, aspirin or naproxen are described. Methods are described for treating gastric acid related disorders and inducing sleep, using pharmaceutical compositions comprising a proton pump inhibitor, a buffering agent, a sleep aid and a pain reliever.

A method may include treating pain, shock, and / or inflammatory conditions in a subject. A method may include using a therapeutically effective amount of an antibody, a lipoxygenase inhibitor, a cytochrome P-450 enzyme inhibitor, and / or an antioxidant configurable to at least partially treat pain, shock, and / or inflammatory conditions in a subject. A method of treating pain, shock, and / or inflammatory conditions in a subject may include inactivating or preventing at least one linoleic acid metabolite to treat certain conditions (e.g., pain, shock, and / or inflammation).

The present invention provides compound having the structure and pharmaceutically acceptable salts or derivatives thereof, as well as compositions including such compounds. The invention also provides methods of (1) preventing pain, (2) treating pain, (3) inducing sedation, (4) treating opiate addiction, (5) treating opiate withdrawal (abstinence syndrome) and / or (6) treating cough in a patient in need thereof by administering a compound or composition of the invention.

The invention relates to the pharmacy field, in particular to powerful inhalation analgesic which is efficient, safe and convenient. A patient with burns has to suffer from burnt surface background pain, operation pain and breakthrough pain. Analgesic in European countries, America and other developed countries accounts for almost half of burn treatment western medicine expenses. But opiates and morphine analgesia medicines have defects, and accordingly medical staff and patients in a burn department urgently need to seek for the analgesia medicines which are used for acute pain, and are capable of instantly performing analgesia functions, safe, efficient, easy, convenient, and economical. The invention provides the inhalation analgesic which is a mixed gas composed of nitrous oxide (N2O) and oxygen (O2). The concentration ranges from 51% to 80%, and the inhalation analgesic can be placed in a steel cylinder of 2-40 litres for use. The invention further provides application of the inhalation analgesic in preparing early analgesia medicines and quick-acting analgesia medicines for war wounds, burns, pre-hospital care, transportation and hospital admission.

It is intended to provide an antiinflammatory and analgesic preparation for external use whereby side effects of a nonsteroidal antiinflammatory and analgesic drug on the skin can be regulated, the nonsteroidal antiinflammatory and analgesic drug can be prevented from degeneration with time due to a dibenzoylmethane derivative contained as an UV absorbent therein, the dibenzoylmethane derivative can be prevented from crystallization and sedimentation due to an oily phase component contained therein, and the inherent effects of the nonsteroidal anti-inflammatory and analgesic drug can be fully exerted without showing skin irritation caused by the oily phase component, an emulsifier and a thickener. The above problem can be solved by providing an antiinflammatory and analgesic preparation for external use which comprises a base for external use containing an oily phase component, a nonsteroidal antiinflammatory and analgesic drug and a dibenzoylmethane derivative and in which the total amount of fatty acid esters in the oily phase component is at least thrice as much as the content of the dibenzoylmethane derivative.

The invention belongs to the technical field of traditional Chinese medicines and particularly relates to a swelling-diminishing pain-relieving medicine and a preparation method thereof. The swelling-diminishing pain-relieving medicine comprises the following components in parts by weight: 75 parts of red sage root, 75 parts of red peony root, 37.5 parts of costus root, 37.5 parts of dried ground beetle, 2 parts of borneol, 37.5 parts of rhizoma corydalis, 7.5 parts of green tangerine peel, 22.5 parts of rhubarb, 5.5 parts of panax notoginseng and 75 parts of angelica sinensis. The medicine is based on the qi and blood differentiation theory of traditional Chinese medicine and combined with modern pharmacological research and comprises the raw medicines such as red sage root, angelica sinensis, panax notoginseng, dried ground beetle and rhizoma corydalis, so that the medicine has the remarkable efficacies of activating blood and removing stasis, diminishing swelling and relieving pain; proved by clinic applications, and the medicine is obvious in treatment effect; the medicine is a pure traditional Chinese medicine preparation and is free of obvious toxic or side effect; the patent medicine is capable of realizing one-time mass production and is convenient to carry and take.

The invention discloses a drug for suppressing tumor and relieving pain, which is prepared from raw materials in the follow weight portion: 2 to 5 portions of toad, 20 to 30 portions of raw angelica dahurica, 20 to 30 portions of curcuma, 10 to 20 portions of raw southern star, 10 to 20 portions of unprocessed radix aconiti, 10 to 20 portions of processed strychnos, 3 to 10 portions of camphor, and 3 to 10 portions of borneol. The drug uses the toad and the curcuma to promote blood circulation and remove blood stasis, search wind and dispel filth, as well as remove obstruction meridian and relieve pain, uses the processed strychnos and the raw southern star to disperse abscess and nodule, and relieve pain and resist tumor, uses the unprocessed radix aconite and the raw angelica dahurica to expel wind and remove dampness, as well as disperse abscess and relieve pain, and uses the borneol and the camphor as medicinal guides for dispelling filth with aroma, and opening orifices and inducing resuscitation. All the medicines are used together to achieve the effects of softening hardness to dissipate stagnation, dispersing abscess and relieving pain, combating poison with poison, and suppressing cancer and stopping pain. Through clinical applications, the pain relieving rate reaches 75 percent, the cancer suppressing rate reaches 66 percent, while the proportion of the side effect is only 13 percent, so the drug has dual functions of relieving pain and suppressing cancer with smaller side effects.

The invention provides a pain-relieving and anti-inflammatory compound sustained-release preparation, which comprises a local anesthetic, a non-steroidal anti-inflammatory drug and a sustained-release preparation consisting of poloxamer 407 and poloxamer 188. The pain-relieving and anti-inflammatory compound sustained-release preparation disclosed by the invention is a non-opioid analgesic, is a dual-effect combined product composed of the local anesthetic and the low-dose non-steroidal anti-inflammatory drug, is specially used for treating postoperative pain and inflammation at an operative site through single administration, and has obvious advantages in efficacy, wherein the non-steroidal anti-inflammatory drug not only has an anti-inflammatory effect, but also can inhibit the formation of an acid environment and normalize the pH value, so that the permeation effect of the local anesthetic is recovered and enhanced, and the drug effect is as long as 4-5 days.

The present invention relates a pharmaceutical composition comprising (a) an opioid analgesic drug and / or an enkephalinase inhibitor, and (b) a selective Nav1.7 inhibitor.

This document provides materials and methods for treating regional pain. For example, compositions including one or more analgesics can be selectively administered (e.g., by image-guided injection) to one or more nerves to treat a mammal having regional pain.

Disclosed are natural compositions including at least five core ingredients that provide pain relief without the side effects of synthetic pain relievers. Further provided are methods of making the disclosed herbal formulations or compositions, and methods of treating mammals that include administering the herbal compositions to a mammal in need thereof.

The invention provides a high-adhesion pain-relieving hydrogel patch and a preparation method thereof. The preparation method comprises the following steps: mixing an acrylamide aqueous solution, dopamine, an additive and a cross-linking agent; after uniformly mixing, adding an initiator at a preset temperature, and obtaining polyacrylamide hydrogel after a preset time; wherein the value range of the preset temperature is 30-70 DEG C; and the value range of the preset time is 0.5 to 3 hours. The analgesic drug molecules are loaded to the polyacrylamide hydrogel, and the high-adhesion pain-relieving hydrogel patch is obtained. The hydrogel patch has natural adhesiveness and antibacterial property, the loaded analgesic drug endows the hydrogel patch with excellent analgesic performance, and the hydrogel patch is simple in preparation method and wide in applicability.

The invention relates to a composition relieving cancer pain. The composition is prepared from flos caryophylli, scorpion, cortex cinnamomi, rhizoma pinelliae, rhizoma cyperi, fructus aurantii, bulbusallii macrostemi and radix polygoni multiflora. The invention further relates to an ointment sticking relieving cancer pain. The ointment sticking comprises a protective layer and the composition, and the protective layer covers the outer side of the composition. The invention further relates to a preparation method of the ointment sticking relieving cancer pain. The composition and the ointmentsticking relieving cancer pain have the advantages that compared with traditional acesodyne, the pain relieving effect of the composition is better, the relieving rate of pain is high, adverse reactions are less, and the quality of life of a patient is improved; and using is convenient, the price is low, and the composition and the ointment sticking are convenient to generalize and apply on a large scale.

The invention provides a novel spray analgesic. The novel spray analgesic consists of the following components in parts by volume: 55-65 parts of dimethyl sulfoxide, 2-4 parts of water-soluble azone,20-30 parts of lidocaine hydrochloride, 5 parts of dexamethasone sodium phosphate, 4 parts of trogopterus dung and 2 parts of chitosan. The novel spray analgesic aims at the problem of long-time chronic pain and can solve the problem that existing analgesics can cause damage to bodies after long-term use.

The invention belongs to the field of drugs, and in particular relates to an externally applied drug for treating cancer pain. The externally applied drug disclosed by the invention is prepared by the following steps of: drying 4.5 parts by weight of paris polyphylla, 13.2-13.5 parts by weight of corydalis tuber, 4-4.5 parts by weight of pollen typhae, 6.5-6.8 parts by weight of trogopterus dung, 10-13.5 parts by weight of prepared frankincense, 13.5-16.5 parts by weight of prepared myrrh, 9.6-10 parts by weight of garden balsam stem, 13.1-13.5 parts by weight of hedyotis diffusa, 6.5-6.7 parts by weight of solanum lyratum and 13.1-13.5 parts by weight of raw oyster shell in the sun, grinding into powder, sieving through a 120-mesh sieve, adjusting to form a pasty mixture by adding boiling water and putting the pasty mixture on a gauze. The externally applied drug is externally applied at affected parts for one time every day; and each time is 3 h. The externally applied drug disclosed by the invention is capable of relieving or alleviating cancer pain, increasing short-term and long-term curative effects, saving the treatment cost, reducing the toxic and side effects due to oral administration of acesodynes and improving the living quality of patients.

The invention relates to an emergency rescue processing system, which comprises an in-vehicle interaction module arranged in an ambulance, an in-hospital interaction module in a hospital and a background interaction module, and is characterized in that the in-vehicle interaction module takes an in-vehicle interaction machine as a carrier to realize interaction between a doctor and a patient in the ambulance; the in-vehicle interaction module comprises an information input unit, a vehicle-mounted doctor diagnosis result submitting unit and a payment unit; the result of the in-vehicle interaction module is transmitted to the background interaction module, the background interaction module transmits the result of the in-vehicle interaction module to the in-hospital interaction module, and the in-hospital interaction module comprises an identity recognition unit, an emergency treatment processing unit and a fee settlement unit. And the information of the in-vehicle interaction module is transmitted to the background processing system and then is fed back to the in-hospital interaction module, so that after entering the hospital, a patient can directly go to an examination room or an injection room for examination or injection of analgesic drugs, and the patient can be treated and cured more timely.

The present invention discloses a drug for treating acute gastritis. The drug is characterized by consisting of the following components: fresh lotus roots, polished round-grained rice, brown sugar and orange peels. The weight ratio of the components are as follows: an appropriate amount of the fresh lotus roots, 100 grams of the polished round-grained rice, a little brown sugar and 50 grams of orange peels. The preparation method is as follows: the fresh lotus roots are cleaned and sliced into thin slices and the polished round-grained rice is cleaned; and the polished round-grained rice, lotus root slices, brown sugar and orange peels are put into a pot, an appropriate amount of fresh water is added, and the raw materials are boiled out using a high heat and then transferred into a low heat until the rice is rotten into porridge. The drug solves the problems that anesthetic and analgesic drugs are large in side effects, long in consumption, most addictive and high in relapse rate, cannot bring the acute gastritis under permanent control, and is suitable for the treatment of patients with acute gastritis.

The invention relates to the field of medical treatment, and in particular relates to anti-inflammatory and analgesic ointment with a good treatment effect and a preparation method thereof. The anti-inflammatory analgesic ointment is prepared from rhizoma corydalis, rheum officinale, pollen typhae, salvia miltiorrhiza, ligusticum wallichii, angelica sinensis, notopterygium root, ampelopsis japonica, lindera aggregata, pangolin scales, terrapin, elephant hide, radix paeoniae rubra, liquorice, keel, olibanum, myrrh, musk, dragon's blood, scorpio and camphor. The anti-inflammatory and analgesic ointment prepared by the invention is suitable for treating various complications caused by appendicitis, relieves the pain of patients, and is also suitable for treating some surgical inflammations.

The invention relates to a traditional Chinese medicine composition for relieving pain of patients after surgery and promoting wound healing. 4-8 parts of Chinese gall, 4-8 parts of Chinese gall, 2-4 parts of asarum, 8-13 parts of double needles, 10-15 parts of dodder, 25-35 parts of astragalus, 25-35 parts of Prunella vulgaris, 25-35 parts of Bupleurum. 22-27 parts of angelica, 5-9 parts of licorice, 13-18 parts of black medicine, 10-15 parts of raw land, 15-25 parts of earthworm, 6-10 parts of safflower, 6-10 parts of rhubarb, 10-10 parts of rehmannia 14 parts, 10-14 parts of turmeric, 3-7 parts of Panax notoginseng. The composition of the invention has an effective rate of 100% for alleviating the pain of patients after surgery, and can effectively promote wound healing, and overcomes the defects of short analgesic time, repeated medication and easy dependence in the prior art.

The invention provides a composition tablet candy for relieving swelling and aching of gum. The composition comprises the following raw materials in parts by weight: 20-30 parts of pepper extract, 25-30 parts of sea-buckthorn freeze-dried powder, 3-7 parts of ginger powder and 3-6 parts of honeysuckle flower powder. The formula of the invention has synergistic effect on relieving swelling and aching of gum. The tablet candy of the invention combines pepper extract with sea-buckthorn freeze-dried powder, fully exerts the advantages of anti-inflammatory and analgesic effect and dietary therapy value, has good taste, can better relieve swelling and aching of gum, and solves the technical problems that the use of analgesic drugs produces side effects, causes certain harm to human health, and can produce dependence on drugs for long-term use. The tablet candy prepared by the invention has good therapeutic effect on swelling and aching of gum symptoms caused by gingivitis caused by endocrine dyscrasia, excessive internal heat or oral bacterial infection and the like. The tablet candy of the invention is a leisure snack, can be conveniently eaten, has multiple consumption scenes, has wide application prospect, and brings huge economic benefit.

An analgesic medication includes an oligonucleotide being a double strand RNA comprising 18 to 70 base pairs, and a pharmaceutical acceptable vehicle for delivering the said oligonucleotide into cells, wherein a dosage of the oligonucleotide in the analgesic is 50 μg to 200 μg / kg per time, and the pharmaceutical acceptable vehicle is selected from a group of polyethyleneimine, lipofectamine and iFect.

The invention belongs to the technical field of natural extracts, particularly relates to a traditional Chinese medicinal extract, and further discloses an extracting method and application thereof in preparation of a medicine for treating migraine. The traditional Chinese medicinal extract disclosed by the invention contains at least 15 weight percent of total polysaccharides and total polyphenols; the obtained extract has clear active ingredients, has a remarkable pain easing effect and has the advantages of safety, no toxic or side effect and the like, and can effectively relieve and treat symptoms of the migraine. Meanwhile, pain easing medicines of different preparations are prepared by utilizing the extract with the clear active ingredients, so that the pain easing medicines are conveniently taken by a patient, and the treatment effect is outstanding.